glucan (1,4-alpha-), branching enzyme 1

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Synonym

1,4-alpha-glucan branching enzyme, GBE1, Brancher enzyme, Glycogen branching enzyme, GBE

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:39.10 cerebellum:37.80 brain stem:- corpus callosum/glia:320.80 pineal gland:148.30 peripheral nerve:30.70 spine:224.60 retina:118.60 eye:23.50 artery/aorta:329.70 vein:66.60 lymphnode:70.80 peripheral blood:54.70 spleen:56.70 thymus:141.70 bone marrow:59 adipose:40.30 bone:243.10 skin:427.20
GeneChip cerebrum:5.66 cerebellum:5.84 brain stem:7.92 corpus callosum/glia:5.88 pineal gland:- peripheral nerve:7.28 spine:6.32 retina:- eye:- artery/aorta:7.81 vein:7.62 lymphnode:6.44 peripheral blood:- spleen:6.62 thymus:6.68 bone marrow:7.36 adipose:8.64 bone:- skin:7.60
CAGE cerebrum:2.69 cerebellum:- brain stem:3.23 corpus callosum/glia:2.86 pineal gland:3.65 peripheral nerve:- spine:3.50 retina:- eye:- artery/aorta:4.80 vein:4.41 lymphnode:3.32 peripheral blood:- spleen:3.21 thymus:2.74 bone marrow:- adipose:5.46 bone:- skin:-
RNA-seq cerebrum:2.58 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.61 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.96 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:94.70 prostate:45.10 ovary:- testis:51.90 heart:114.90 muscle:241.10 esophagus:- stomach:21.20 intestine:32.40 colon:-     liver/hepato:84.40        lung:34.20    bladder:125.60 kidney:93.60 pituitary:- thyroid/parathyroid:- adrenal gland:203.10 pancreas:62.20 breast:55.80 salivary:-
GeneChip uterus:7.15 placenta:7.33 prostate:6.93 ovary:7.09 testis:5.89 heart:8.22 muscle:9.21 esophagus:7.28 stomach:6.32 intestine:7.08 colon:5.98 liver/hepato:8.58 lung:6.65 bladder:- kidney:7.78 pituitary:7.19 thyroid/parathyroid:6.91 adrenal gland:8.55 pancreas:6.30 breast:7.31 salivary:7.07
CAGE uterus:3.64 placenta:3.80 prostate:3.29 ovary:3.92 testis:3.25 heart:5.15 muscle:5.65 esophagus:3.44 stomach:- intestine:3.18 colon:3.43     liver/hepato:4.67    lung:3.99 bladder:4.39 kidney:4.25 pituitary:3.58 thyroid/parathyroid:3.62 adrenal gland:- pancreas:3.10 breast:5.89 salivary:3.88
RNA-seq uterus:- placenta:- prostate:3.96 ovary:3.99 testis:3.81 heart:4.60 muscle:5.48 esophagus:- stomach:- intestine:- colon:4.82     liver/hepato:4.34        lung:4.51    bladder:- kidney:4.82 pituitary:- thyroid/parathyroid:4.97 adrenal gland:3.41 pancreas:- breast:6.05 salivary:-

Gene Information

IDs

Refseq ID NM_000158
Gene ID 2632
Unigene ID Hs.436062
Probe set ID 203282_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000114480
GTEx ID ENSG00000114480

Orthologous Gene

Mouse[1]  NM_028803
Rat[1]  NM_028803

Chromosomal Region

3p12.2  [81,538,850  -  81,811,312]

Gene Family (Interpro ID)

IPR017853  Glycoside hydrolase, catalytic core
IPR013781  Glycoside hydrolase, subgroup, catalytic core
IPR006047  Glycosyl hydrolase, family 13, catalytic domain
IPR006589  Glycosyl hydrolase, family 13, subfamily, catalytic domain

Link to Pubmed  (Pubmed ID)

6220706
8059607
8463281
8613547
9851430
10384399
10533307
10545044
10762170
12477932
14557872
14702039
15019703
15452297
15489334
15592455
16169070
16254601
17915577
17994551
18289670
18392749
19056867
19322201
19913121
20058079
20300197
20301758
20379614
20628086
20800603
20816195
21139048
21252943
21890473
21906983
21988832
22305237
22797925
22939629
22943850
23000965
23034915
23218673
23285490
23455924
24248152
24501781
24654937

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0006091  generation of precursor metabolites and energy
GO:0006006  glucose metabolic process
GO:0005978  glycogen biosynthetic process
GO:0005977  glycogen metabolic process

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0003844  1,4-alpha-glucan branching enzyme activity
GO:0043169  cation binding
GO:0004553  hydrolase activity, hydrolyzing O-glycosyl compounds