GDP dissociation inhibitor 2

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Synonym

GDI2, GDI-2, Rab GDI beta, FLJ16452, rab GDP-dissociation, GDP dissociation inhibitor 2, RABGDIB, Guanosine diphosphate dissociation inhibitor 2, Rab GDP dissociation inhibitor beta

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:384 cerebellum:277.10 brain stem:- corpus callosum/glia:1108.10 pineal gland:- peripheral nerve:92 spine:336.90 retina:355.90 eye:158.70 artery/aorta:929.20 vein:266.60 lymphnode:91 peripheral blood:601.20 spleen:1058.80 thymus:824.60 bone marrow:177.10 adipose:363 bone:524.60 skin:398.40
GeneChip cerebrum:9 cerebellum:8.87 brain stem:9.29 corpus callosum/glia:9.20 pineal gland:- peripheral nerve:9.51 spine:9.33 retina:- eye:- artery/aorta:9.29 vein:9.39 lymphnode:9.74 peripheral blood:- spleen:9.45 thymus:9.81 bone marrow:9.37 adipose:9.60 bone:- skin:9.66
CAGE cerebrum:4.93 cerebellum:- brain stem:5.08 corpus callosum/glia:5.05 pineal gland:5.04 peripheral nerve:- spine:5.51 retina:- eye:- artery/aorta:5.23 vein:5.23 lymphnode:5.61 peripheral blood:- spleen:5.42 thymus:5.43 bone marrow:- adipose:5.66 bone:- skin:-
RNA-seq cerebrum:6.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.47 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.91 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:647 placenta:200.40 prostate:349.20 ovary:149.10 testis:246.60 heart:255.40 muscle:100.50 esophagus:- stomach:488.60 intestine:712.80 colon:424     liver/hepato:126.70        lung:479    bladder:1633 kidney:374.30 pituitary:- thyroid/parathyroid:491.20 adrenal gland:507.90 pancreas:62.20 breast:185.90 salivary:-
GeneChip uterus:9.86 placenta:9.04 prostate:9.76 ovary:10.04 testis:9.22 heart:8.82 muscle:8.93 esophagus:9.56 stomach:9.29 intestine:9.36 colon:9.32 liver/hepato:9.31 lung:9.51 bladder:- kidney:9.13 pituitary:9.22 thyroid/parathyroid:9.33 adrenal gland:9.05 pancreas:10.07 breast:9.65 salivary:9.18
CAGE uterus:5.22 placenta:5.10 prostate:5.28 ovary:5.37 testis:4.94 heart:5.24 muscle:4.78 esophagus:5.31 stomach:- intestine:5.69 colon:5.39     liver/hepato:5.75    lung:5.44 bladder:5.45 kidney:5.34 pituitary:5.27 thyroid/parathyroid:5.43 adrenal gland:- pancreas:5.61 breast:5.68 salivary:5.02
RNA-seq uterus:- placenta:- prostate:6.71 ovary:6.95 testis:6.67 heart:5.17 muscle:6.58 esophagus:- stomach:- intestine:- colon:6.87     liver/hepato:6.15        lung:6.12    bladder:- kidney:6.40 pituitary:- thyroid/parathyroid:6.45 adrenal gland:6.35 pancreas:- breast:6.77 salivary:-

Gene Information

IDs

Refseq ID NM_001494
Gene ID 2665
Unigene ID Hs.299055
Probe set ID 200009_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000057608
GTEx ID ENSG00000057608

Orthologous Gene

Mouse[12]  NM_008112
Rat [0]  

Chromosomal Region

10p15.1  [5,807,186  -  5,884,095]

Gene Family (Interpro ID)

IPR018203  GDP dissociation inhibitor
IPR000806  Rab GDI protein

Link to Pubmed  (Pubmed ID)

7513052
7543319
7585614
7929030
8575461
9434952
10512627
10996854
11771757
11809807
12477932
12493773
14702039
15489334
16009940
16130169
16344560
16385451
17507299
18781797
19056867
19135240
19322201
19570034
19738201
20360068
20562859
21139048
21565611
21890473
21906983
21963094
21987572
21988832
22053931
22505724
22586326
22863883
22939629
23000965
23184937
23727862
23824909
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0015031  protein transport
GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007165  signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005794  Golgi apparatus
GO:0016020  membrane

Molecular Function

GO:0005515  protein binding
GO:0005093  Rab GDP-dissociation inhibitor activity
GO:0005097  Rab GTPase activator activity