UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1

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Synonym

b4Gal-T1, MGC50983, beta4Gal-T1, Beta4Gal-T1, Beta-1,4-galactosyltransferase 1, B4GAL-T1, GTB, B4GALT1, DKFZp686N19253, GGTB2, Beta-1,4-GalTase 1, GT1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:11.90 cerebellum:12.60 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:152.80 artery/aorta:119.90 vein:- lymphnode:151.70 peripheral blood:36.40 spleen:132.30 thymus:25.80 bone marrow:157.40 adipose:161.30 bone:64 skin:86.40
GeneChip cerebrum:5.83 cerebellum:6.11 brain stem:5.74 corpus callosum/glia:6.20 pineal gland:- peripheral nerve:6.36 spine:6.20 retina:- eye:- artery/aorta:7 vein:7.11 lymphnode:7.13 peripheral blood:- spleen:6.82 thymus:6.69 bone marrow:6.82 adipose:6.82 bone:- skin:6.85
CAGE cerebrum:2.49 cerebellum:- brain stem:2.73 corpus callosum/glia:3.04 pineal gland:2.63 peripheral nerve:- spine:3.04 retina:- eye:- artery/aorta:4.80 vein:4.70 lymphnode:4.88 peripheral blood:- spleen:4.80 thymus:4.09 bone marrow:- adipose:4.65 bone:- skin:-
RNA-seq cerebrum:1.89 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.95 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.55 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:229.50 prostate:33.80 ovary:- testis:103.80 heart:178.80 muscle:- esophagus:- stomach:63.70 intestine:- colon:245.90     liver/hepato:63.30        lung:229.70    bladder:- kidney:187.10 pituitary:- thyroid/parathyroid:491.20 adrenal gland:50.80 pancreas:53.30 breast:195.20 salivary:-
GeneChip uterus:6.92 placenta:7.05 prostate:6.95 ovary:6.95 testis:7.15 heart:6.82 muscle:6.26 esophagus:7.17 stomach:6.80 intestine:6.68 colon:6.67 liver/hepato:7.14 lung:6.75 bladder:- kidney:7.03 pituitary:6.77 thyroid/parathyroid:7.49 adrenal gland:7.17 pancreas:6.91 breast:6.85 salivary:7.17
CAGE uterus:4.41 placenta:5.47 prostate:4.35 ovary:5.18 testis:5.02 heart:4.77 muscle:3.57 esophagus:4.37 stomach:- intestine:4.11 colon:4.39     liver/hepato:5.57    lung:5.01 bladder:4.43 kidney:4.60 pituitary:3.64 thyroid/parathyroid:4.76 adrenal gland:- pancreas:4.14 breast:4.73 salivary:4.57
RNA-seq uterus:- placenta:- prostate:4.59 ovary:5.90 testis:5.13 heart:4.16 muscle:3.48 esophagus:- stomach:- intestine:- colon:4.20     liver/hepato:5.62        lung:6.06    bladder:- kidney:4.97 pituitary:- thyroid/parathyroid:5.80 adrenal gland:4.92 pancreas:- breast:4.30 salivary:-

Gene Information

IDs

Refseq ID NM_001497
Gene ID 2683
Unigene ID Hs.272011
Probe set ID 201883_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000086062
GTEx ID ENSG00000086062

Orthologous Gene

Mouse[1]  NM_022305
Rat[2]  NM_053287

Chromosomal Region

9p21.1  [33,104,080  -  33,167,354]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

33805
1384956
1714903
1903938
2120039
2124683
2187500
2541446
2542563
2649653
2829950
3091013
3094506
3098628
3144273
3917437
6121819
7540104
7579794
7744867
8540625
9597550
10580128
10900002
11295846
11506180
11901181
11947697
12477932
15164053
15611127
15668241
16157350
16502470
16675551
16786197
17021253
18029348
18215327
18314154
18330979
18929424
19056867
19106107
19204726
19261593
19322201
19946888
20202494
20301507
20360068
20378551
20379614
20467438
20490888
20619088
20655926
20851383
20886274
21139048
21750942
21963094
22740701
22847114
22927297
22939629
22982306
23263486
23382691
23583406
23744354

Gene Ontology  (GO ID)

Biological Process

GO:0002526  acute inflammatory response
GO:0060055  angiogenesis involved in wound healing
GO:0007339  binding of sperm to zona pellucida
GO:0048754  branching morphogenesis of a tube
GO:0005975  carbohydrate metabolic process
GO:0007155  cell adhesion
GO:0044267  cellular protein metabolic process
GO:0045136  development of secondary sexual characteristics
GO:0002064  epithelial cell development
GO:0030198  extracellular matrix organization
GO:0006012  galactose metabolic process
GO:0030203  glycosaminoglycan metabolic process
GO:0018146  keratan sulfate biosynthetic process
GO:0042339  keratan sulfate metabolic process
GO:0005989  lactose biosynthetic process
GO:0050900  leukocyte migration
GO:0030879  mammary gland development
GO:0032504  multicellular organism reproduction
GO:0008285  negative regulation of cell proliferation
GO:0007219  Notch signaling pathway
GO:0009312  oligosaccharide biosynthetic process
GO:0007341  penetration of zona pellucida
GO:0060058  positive regulation of apoptosis involved in mammary gland involution
GO:0060054  positive regulation of epithelial cell proliferation involved in wound healing
GO:0043687  post-translational protein modification
GO:0018279  protein amino acid N-linked glycosylation via asparagine
GO:0060046  regulation of acrosome reaction
GO:0051270  regulation of cellular component movement
GO:0007338  single fertilization

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0031526  brush border membrane
GO:0030057  desmosome
GO:0009897  external side of plasma membrane
GO:0005576  extracellular region
GO:0030112  glycocalyx
GO:0005794  Golgi apparatus
GO:0032580  Golgi cisterna membrane
GO:0000139  Golgi membrane
GO:0000138  Golgi trans cisterna
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0043014  alpha-tubulin binding
GO:0003831  beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
GO:0048487  beta-tubulin binding
GO:0008092  cytoskeletal protein binding
GO:0008378  galactosyltransferase activity
GO:0004461  lactose synthase activity
GO:0046872  metal ion binding
GO:0003945  N-acetyllactosamine synthase activity
GO:0042803  protein homodimerization activity
GO:0035250  UDP-galactosyltransferase activity