growth hormone receptor

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Synonym

GHBP, GHR, growth hormone receptor, Somatotropin receptor, Growth hormone receptor precursor, GH receptor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:3.69

cerebellum:3.38

brain stem:3.81

corpus callosum/glia:3.74

pineal gland:-

peripheral nerve:5.51

spine:4.35

retina:-

eye:-

artery/aorta:6.85

vein:5.77

lymphnode:4.53

peripheral blood:-

spleen:5

thymus:4.42

bone marrow:4.83

adipose:9.30

bone:-

skin:6.58

CAGE

cerebrum:1.35

cerebellum:-

brain stem:1.48

corpus callosum/glia:1.23

pineal gland:1.81

peripheral nerve:-

spine:1.59

retina:-

eye:-

artery/aorta:2.81

vein:3.29

lymphnode:1.62

peripheral blood:-

spleen:2.11

thymus:0.74

bone marrow:-

adipose:4.75

bone:-

skin:-

RNA-seq

cerebrum:0.13

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.50

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.73

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:5.46

placenta:5.19

prostate:7.39

ovary:5.69

testis:3.79

heart:6.46

muscle:8.26

esophagus:5.07

stomach:5.36

intestine:5.47

colon:4.72

liver/hepato:10.09

lung:5.61

bladder:-

kidney:6.23

pituitary:3.55

thyroid/parathyroid:5.91

adrenal gland:6.01

pancreas:4.71

breast:6.88

salivary:4.33

CAGE

uterus:2.70

placenta:2.48

prostate:3.21

ovary:2.69

testis:1.89

heart:2.91

muscle:3.97

esophagus:2.07

stomach:-

intestine:1.94

colon:2.64

liver/hepato:4.67

lung:2.22

bladder:2.48

kidney:2.69

pituitary:1.36

thyroid/parathyroid:2.12

adrenal gland:-

pancreas:1.59

breast:4.43

salivary:1.28

RNA-seq

uterus:-

placenta:-

prostate:0.75

ovary:0.71

testis:0.26

heart:0.41

muscle:2.73

esophagus:-

stomach:-

intestine:-

colon:0.69

liver/hepato:1.27

lung:0.78

bladder:-

kidney:0.40

pituitary:-

thyroid/parathyroid:1.18

adrenal gland:0

pancreas:-

breast:3.80

salivary:-

IDs

Refseq ID	NM_000163
Gene ID	2690
Unigene ID	-
Probe set ID	205498_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000112964
GTEx ID	ENSG00000112964

Orthologous Gene

Mouse[5]	NM_001048147, NM_001048178, NM_010284
Rat [0]

Chromosomal Region

5p13.1 [42,423,879 - 42,721,979]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold

Gene Ontology (GO ID)

Biological Process

GO:0006103	2-oxoglutarate metabolic process
GO:0042977	activation of JAK2 kinase activity
GO:0000187	activation of MAPK activity
GO:0000255	allantoin metabolic process
GO:0060351	cartilage development involved in endochondral bone morphogenesis
GO:0032870	cellular response to hormone stimulus
GO:0032869	cellular response to insulin stimulus
GO:0006101	citrate metabolic process
GO:0006600	creatine metabolic process
GO:0046449	creatinine metabolic process
GO:0006897	endocytosis
GO:0006631	fatty acid metabolic process
GO:0060396	growth hormone receptor signaling pathway
GO:0009755	hormone-mediated signaling pathway
GO:0048009	insulin-like growth factor receptor signaling pathway
GO:0006549	isoleucine metabolic process
GO:0007259	JAK-STAT cascade
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
GO:0044236	multicellular organismal metabolic process
GO:0006107	oxaloacetate metabolic process
GO:0045597	positive regulation of cell differentiation
GO:0040018	positive regulation of multicellular organism growth
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0031623	receptor internalization
GO:0040014	regulation of multicellular organism growth
GO:0046898	response to cycloheximide
GO:0032355	response to estradiol stimulus
GO:0032094	response to food
GO:0051384	response to glucocorticoid stimulus
GO:0070555	response to interleukin-1
GO:0043278	response to morphine
GO:0006105	succinate metabolic process
GO:0019530	taurine metabolic process
GO:0006573	valine metabolic process

Cellular Component

GO:0043025	cell soma
GO:0009986	cell surface
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0019898	extrinsic to membrane
GO:0070195	growth hormone receptor complex
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0043235	receptor complex

Molecular Function

GO:0019838	growth factor binding
GO:0004903	growth hormone receptor activity
GO:0017046	peptide hormone binding
GO:0070064	proline-rich region binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding
GO:0042169	SH2 domain binding

growth hormone receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function