poly(A) binding protein, cytoplasmic 1

Synonym

PABPL1, PABPC2, PABP1, PAB1, Poly(A)-binding protein 1, PABP 1, poly(A) binding protein, cytoplasmic 1, PABP, Polyadenylate-binding protein 1, PABPC1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:296.30

cerebellum:25.20

brain stem:-

corpus callosum/glia:1108.10

pineal gland:-

peripheral nerve:1073.50

spine:673.80

retina:474.60

eye:605.30

artery/aorta:2188.20

vein:199.90

lymphnode:808.80

peripheral blood:838.10

spleen:661.70

thymus:605.50

bone marrow:551.10

adipose:161.30

bone:601.40

skin:1161.60

GeneChip

cerebrum:9.31

cerebellum:9.55

brain stem:9.38

corpus callosum/glia:10.04

pineal gland:-

peripheral nerve:10.11

spine:10.10

retina:-

eye:-

artery/aorta:10.44

vein:10.12

lymphnode:11.29

peripheral blood:-

spleen:11.14

thymus:11.14

bone marrow:10.93

adipose:11.06

bone:-

skin:10.90

CAGE

cerebrum:5.73

cerebellum:-

brain stem:5.79

corpus callosum/glia:6.06

pineal gland:5.82

peripheral nerve:-

spine:6.56

retina:-

eye:-

artery/aorta:6.58

vein:6.73

lymphnode:7.36

peripheral blood:-

spleen:7.19

thymus:7.05

bone marrow:-

adipose:6.67

bone:-

skin:-

RNA-seq

cerebrum:5.25

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:7.79

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:7.69

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:373.60

placenta:171.20

prostate:270.30

ovary:670.70

testis:540.80

heart:370.40

muscle:100.50

esophagus:-

stomach:2272.90

intestine:453.60

colon:1899.40

liver/hepato:274.40

lung:430.10

bladder:1004.90

kidney:145.60

pituitary:232

thyroid/parathyroid:982.50

adrenal gland:304.70

pancreas:320.10

breast:1486.90

salivary:5911.30

GeneChip

uterus:10.95

placenta:9.35

prostate:11.36

ovary:11.23

testis:12.02

heart:9.52

muscle:8.07

esophagus:11.71

stomach:10.88

intestine:9.90

colon:10.26

liver/hepato:10.28

lung:10.53

bladder:-

kidney:10

pituitary:9.79

thyroid/parathyroid:10.58

adrenal gland:10.55

pancreas:10.39

breast:11.19

salivary:12.01

CAGE

uterus:6.86

placenta:6.17

prostate:6.86

ovary:6.85

testis:7.03

heart:5.78

muscle:5.31

esophagus:7.28

stomach:-

intestine:6.92

colon:6.53

liver/hepato:6.56

lung:6.87

bladder:7.10

kidney:6.01

pituitary:5.82

thyroid/parathyroid:6.42

adrenal gland:-

pancreas:6.56

breast:6.59

salivary:7.76

RNA-seq

uterus:-

placenta:-

prostate:8.35

ovary:7.87

testis:8.06

heart:5.31

muscle:5.57

esophagus:-

stomach:-

intestine:-

colon:7.96

liver/hepato:5.94

lung:7.89

bladder:-

kidney:6.25

pituitary:-

thyroid/parathyroid:6.56

adrenal gland:7.30

pancreas:-

breast:6.99

salivary:-

IDs

Refseq ID	NM_002568
Gene ID	26986
Unigene ID	Hs.387804
Probe set ID	215157_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000070756
GTEx ID	ENSG00000070756

Orthologous Gene

Mouse [0]
Rat [0]

Chromosomal Region

8q22.3 [101,698,044 - 101,735,037]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000504	RNA recognition motif, RNP-1
IPR003954	RNA recognition, domain 1

Gene Ontology (GO ID)

Biological Process

GO:0044267	cellular protein metabolic process
GO:0010467	gene expression
GO:0031047	gene silencing by RNA
GO:0016071	mRNA metabolic process
GO:0006378	mRNA polyadenylation
GO:0048255	mRNA stabilization
GO:0000398	nuclear mRNA splicing, via spliceosome
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0045727	positive regulation of translation
GO:0016070	RNA metabolic process
GO:0006412	translation
GO:0006413	translational initiation

Cellular Component

GO:0071013	catalytic step 2 spliceosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005634	nucleus
GO:0030529	ribonucleoprotein complex
GO:0010494	stress granule

Molecular Function

GO:0000166	nucleotide binding
GO:0008143	poly(A) RNA binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0008494	translation activator activity

poly(A) binding protein, cytoplasmic 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function