nerve growth factor receptor (TNFRSF16) associated protein 1

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Synonym

Bex, Protein BEX3, HGR74, BEX3, p75NTR-associated cell death executor, DXS6984E, NADE, Ovarian granulosa cell 13.0 kDa protein HGR74, Nerve growth factor receptor-associated protein 1, Brain-expressed X-linked protein 3, NGFRAP1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:12.02 cerebellum:11.87 brain stem:11.90 corpus callosum/glia:11.42 pineal gland:- peripheral nerve:11.41 spine:11.81 retina:- eye:- artery/aorta:10.47 vein:10.76 lymphnode:9.37 peripheral blood:- spleen:10.21 thymus:10.30 bone marrow:8.60 adipose:10.07 bone:- skin:9.48
CAGE cerebrum:5.82 cerebellum:- brain stem:5.24 corpus callosum/glia:5.04 pineal gland:5.81 peripheral nerve:- spine:5.74 retina:- eye:- artery/aorta:5.10 vein:4.31 lymphnode:3.51 peripheral blood:- spleen:4.24 thymus:4.09 bone marrow:- adipose:3.77 bone:- skin:-
RNA-seq cerebrum:6.82 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.96 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.75 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:10.88 placenta:10.61 prostate:11.11 ovary:11.25 testis:11.19 heart:10.90 muscle:8.14 esophagus:9.92 stomach:10.09 intestine:9.94 colon:10.12 liver/hepato:9.54 lung:10.35 bladder:- kidney:11.44 pituitary:12 thyroid/parathyroid:11.86 adrenal gland:11.75 pancreas:10.48 breast:10.30 salivary:10.48
CAGE uterus:4.54 placenta:5.04 prostate:4.62 ovary:5.30 testis:5.22 heart:5.16 muscle:2.96 esophagus:4.27 stomach:- intestine:3.22 colon:4.14     liver/hepato:3.48    lung:4.59 bladder:4.42 kidney:4.74 pituitary:5.59 thyroid/parathyroid:5.51 adrenal gland:- pancreas:4.50 breast:4.34 salivary:3.84
RNA-seq uterus:- placenta:- prostate:3.85 ovary:5.58 testis:4.36 heart:1.95 muscle:0.68 esophagus:- stomach:- intestine:- colon:2.94     liver/hepato:0.98        lung:3.94    bladder:- kidney:4.28 pituitary:- thyroid/parathyroid:6.13 adrenal gland:3.99 pancreas:- breast:3.31 salivary:-

Gene Information

IDs

Refseq ID NM_014380
Gene ID 27018
Unigene ID -
Probe set ID 217963_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000166681
GTEx ID ENSG00000166681

Orthologous Gene

Mouse[3]  NM_001110233, NM_001110234, NM_009750
Rat [0]  

Chromosomal Region

Xq22.2  [102,631,268  -  102,633,005]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2171551
7757816
10514511
10544233
10764727
11238738
11278287
11830582
12477932
12739005
12787561
15178455
15489334
15772651
15958283
16189514
16221301
16777077
17207965
17355907
18029348
21139048
21988832

Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0006917  induction of apoptosis
GO:0008625  induction of apoptosis via death domain receptors
GO:0007275  multicellular organismal development
GO:0048011  nerve growth factor receptor signaling pathway
GO:0043281  regulation of caspase activity

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0008656  caspase activator activity
GO:0005123  death receptor binding
GO:0046872  metal ion binding
GO:0005515  protein binding