forkhead box D3

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Synonym

HNF3/FH transcription factor genesis, forkhead box D3, Genesis, FOXD3, Forkhead box protein D3, HFH2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.27 cerebellum:3.31 brain stem:3.23 corpus callosum/glia:3.16 pineal gland:- peripheral nerve:3.57 spine:3.15 retina:- eye:- artery/aorta:3.41 vein:3.45 lymphnode:3.30 peripheral blood:- spleen:3.04 thymus:3.11 bone marrow:3.39 adipose:3.37 bone:- skin:3.31
CAGE cerebrum:0.00 cerebellum:- brain stem:0.34 corpus callosum/glia:0 pineal gland:0.72 peripheral nerve:- spine:0.17 retina:- eye:- artery/aorta:0.18 vein:1.03 lymphnode:0.09 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:0.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.59 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:38.30 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.23 placenta:3.19 prostate:3.09 ovary:3.23 testis:3.25 heart:3.33 muscle:3.32 esophagus:3.29 stomach:3.16 intestine:3.37 colon:3.48 liver/hepato:3.25 lung:3.27 bladder:- kidney:3.21 pituitary:3.37 thyroid/parathyroid:3.28 adrenal gland:3.27 pancreas:3.54 breast:3.15 salivary:3.42
CAGE uterus:0.58 placenta:0 prostate:1.03 ovary:0.26 testis:0.79 heart:0.59 muscle:0.30 esophagus:1.44 stomach:- intestine:0.61 colon:0.52     liver/hepato:0    lung:0.05 bladder:1.21 kidney:0 pituitary:0 thyroid/parathyroid:0.06 adrenal gland:- pancreas:0 breast:0.55 salivary:0.36
RNA-seq uterus:- placenta:- prostate:1.11 ovary:0.11 testis:0.46 heart:0.05 muscle:0.25 esophagus:- stomach:- intestine:- colon:1.07     liver/hepato:0.01        lung:0.12    bladder:- kidney:0.03 pituitary:- thyroid/parathyroid:0.18 adrenal gland:0.09 pancreas:- breast:0.05 salivary:-

Gene Information

IDs

Refseq ID NM_012183
Gene ID 27022
Unigene ID Hs.546573
Probe set ID 208500_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000187140
GTEx ID ENSG00000187140

Orthologous Gene

Mouse[1]  NM_010425
Rat[1]  NM_010425

Chromosomal Region

1p31.3  [63,788,730  -  63,790,797]

Gene Family (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

8499623
11179011
11891324
16098053
16710414
19034670
20332228
21478267
22815627
22887036
23058321
23543055
23858437
24632201

Gene Ontology  (GO ID)

Biological Process

GO:0048846  axon extension involved in axon guidance
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0051216  cartilage development
GO:0001892  embryonic placenta development
GO:0048484  enteric nervous system development
GO:0001701  in utero embryonic development
GO:0050935  iridophore differentiation
GO:0001822  kidney development
GO:0048937  lateral line nerve glial cell development
GO:0030318  melanocyte differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001755  neural crest cell migration
GO:0007389  pattern specification process
GO:0007422  peripheral nervous system development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0051090  regulation of transcription factor activity
GO:0048485  sympathetic nervous system development
GO:0001829  trophectodermal cell differentiation

Cellular Component

GO:0000790  nuclear chromatin
GO:0005667  transcription factor complex

Molecular Function

GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding