galactosidase, alpha

Synonym

Alpha-D-galactosidase A, Alpha-galactosidase A precursor, galactosidase, alpha, GLA, Alpha-D-galactoside galactohydrolase, Melibiase, GALA, Agalsidase alfa

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:19

cerebellum:25.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:61.30

spine:112.30

retina:-

eye:23.50

artery/aorta:30

vein:-

lymphnode:50.60

peripheral blood:164

spleen:18.90

thymus:-

bone marrow:19.70

adipose:80.70

bone:12.80

skin:24

GeneChip

cerebrum:6.10

cerebellum:5.98

brain stem:6.51

corpus callosum/glia:6.06

pineal gland:-

peripheral nerve:6.66

spine:6.33

retina:-

eye:-

artery/aorta:6.89

vein:6.64

lymphnode:6.78

peripheral blood:-

spleen:6.45

thymus:6.97

bone marrow:7.42

adipose:6.79

bone:-

skin:6.97

CAGE

cerebrum:1.91

cerebellum:-

brain stem:2.38

corpus callosum/glia:2.19

pineal gland:1.73

peripheral nerve:-

spine:2.63

retina:-

eye:-

artery/aorta:2.45

vein:2.27

lymphnode:2.57

peripheral blood:-

spleen:3.13

thymus:2.31

bone marrow:-

adipose:3.19

bone:-

skin:-

RNA-seq

cerebrum:2.34

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.88

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.13

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:18.20

prostate:45.10

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:21.20

intestine:64.80

colon:8.50

liver/hepato:10.60

lung:205.30

bladder:-

kidney:20.80

pituitary:116

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:17.80

breast:37.20

salivary:-

GeneChip

uterus:7.02

placenta:7.04

prostate:6.69

ovary:6.95

testis:5.97

heart:6.36

muscle:6.17

esophagus:6.71

stomach:6.43

intestine:6.56

colon:6.63

liver/hepato:6.03

lung:7.49

bladder:-

kidney:6.64

pituitary:6.79

thyroid/parathyroid:6.62

adrenal gland:7.46

pancreas:6.07

breast:7.14

salivary:6.61

CAGE

uterus:2.55

placenta:2.93

prostate:2.36

ovary:2.33

testis:1.91

heart:2.23

muscle:1.60

esophagus:2.29

stomach:-

intestine:3.17

colon:2.24

liver/hepato:2.91

lung:2.96

bladder:2.60

kidney:3.45

pituitary:2.31

thyroid/parathyroid:2.21

adrenal gland:-

pancreas:2.18

breast:2.69

salivary:2.39

RNA-seq

uterus:-

placenta:-

prostate:3.50

ovary:3.14

testis:3.15

heart:2.04

muscle:1.05

esophagus:-

stomach:-

intestine:-

colon:3.33

liver/hepato:3.07

lung:3.92

bladder:-

kidney:4.71

pituitary:-

thyroid/parathyroid:2.67

adrenal gland:3.43

pancreas:-

breast:3.31

salivary:-

IDs

Refseq ID	NM_000169
Gene ID	2717
Unigene ID	Hs.69089
Probe set ID	214430_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000102393
GTEx ID	ENSG00000102393

Orthologous Gene

Mouse[2]	NM_013463
Rat[1]	NM_001108820

Chromosomal Region

Xq22.1 [100,652,791 - 100,662,913]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000111	Glycoside hydrolase, clan GH-D
IPR002241	Glycoside hydrolase, family 27

Gene Ontology (GO ID)

Biological Process

GO:0016139	glycoside catabolic process
GO:0046479	glycosphingolipid catabolic process
GO:0006687	glycosphingolipid metabolic process
GO:0046477	glycosylceramide catabolic process
GO:0045019	negative regulation of nitric oxide biosynthetic process
GO:0051001	negative regulation of nitric-oxide synthase activity
GO:0009311	oligosaccharide metabolic process
GO:0006665	sphingolipid metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005794	Golgi apparatus
GO:0043202	lysosomal lumen
GO:0005764	lysosome

Molecular Function

GO:0004557	alpha-galactosidase activity
GO:0003824	catalytic activity
GO:0016936	galactoside binding
GO:0016787	hydrolase activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0005102	receptor binding

galactosidase, alpha

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function