guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

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Synonym

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:17.80

cerebellum:25.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:8.68

cerebellum:8.71

brain stem:8.30

corpus callosum/glia:7.44

pineal gland:-

peripheral nerve:8.10

spine:7.27

retina:-

eye:-

artery/aorta:4.54

vein:5.43

lymphnode:4.23

peripheral blood:-

spleen:3.85

thymus:3.99

bone marrow:4.27

adipose:4.37

bone:-

skin:4.30

CAGE

cerebrum:5.84

cerebellum:-

brain stem:5.60

corpus callosum/glia:5.62

pineal gland:4.13

peripheral nerve:-

spine:5.56

retina:-

eye:-

artery/aorta:2.86

vein:2.03

lymphnode:1.87

peripheral blood:-

spleen:1.92

thymus:1.29

bone marrow:-

adipose:1.25

bone:-

skin:-

RNA-seq

cerebrum:5.87

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.43

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.12

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.37

placenta:4.17

prostate:4.42

ovary:4.04

testis:4.84

heart:5.38

muscle:4.19

esophagus:4.28

stomach:4.86

intestine:4.65

colon:5.29

liver/hepato:4.65

lung:3.97

bladder:-

kidney:4.09

pituitary:5.91

thyroid/parathyroid:4.07

adrenal gland:4.24

pancreas:4.83

breast:3.97

salivary:4.41

CAGE

uterus:2.37

placenta:0.81

prostate:3.21

ovary:1.86

testis:3.81

heart:3.50

muscle:0.98

esophagus:1.80

stomach:-

intestine:2.76

colon:3.67

liver/hepato:2.81

lung:1.36

bladder:3.70

kidney:1.61

pituitary:4.71

thyroid/parathyroid:1.23

adrenal gland:-

pancreas:1.98

breast:1.53

salivary:1.00

RNA-seq

uterus:-

placenta:-

prostate:1.69

ovary:0.16

testis:2.61

heart:1.01

muscle:0.17

esophagus:-

stomach:-

intestine:-

colon:2.95

liver/hepato:0.23

lung:0.17

bladder:-

kidney:0.26

pituitary:-

thyroid/parathyroid:0.25

adrenal gland:0.42

pancreas:-

breast:0.05

salivary:-

IDs

Refseq ID	NM_020988
Gene ID	2775
Unigene ID	Hs.644524
Probe set ID	204762_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000087258
GTEx ID	ENSG00000087258

Orthologous Gene

Mouse[2]	NM_001113384, NM_010308
Rat [0]

Chromosomal Region

16q12.2 [56,225,302 - 56,391,354]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002975	Fungal G-protein, alpha subunit
IPR001408	G-protein alpha subunit, group I
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0007568	aging
GO:0007212	dopamine receptor signaling pathway
GO:0030900	forebrain development
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007626	locomotory behavior
GO:0006936	muscle contraction
GO:0051926	negative regulation of calcium ion transport
GO:0031175	neuron projection development
GO:0043547	positive regulation of GTPase activity
GO:0008016	regulation of heart contraction
GO:0034097	response to cytokine stimulus
GO:0042493	response to drug
GO:0042542	response to hydrogen peroxide
GO:0043278	response to morphine

Cellular Component

GO:0031234	extrinsic to internal side of plasma membrane
GO:0005834	heterotrimeric G-protein complex
GO:0043005	neuron projection
GO:0005886	plasma membrane

Molecular Function

GO:0051430	corticotropin-releasing hormone receptor 1 binding
GO:0031683	G-protein beta/gamma-subunit binding
GO:0005525	GTP binding
GO:0003924	GTPase activity
GO:0031821	metabotropic serotonin receptor binding
GO:0046872	metal ion binding
GO:0031852	mu-type opioid receptor binding
GO:0004871	signal transducer activity

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function