amylase, alpha 2A (pancreatic)

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Synonym

AMY2A, AMY2, Pancreatic alpha-amylase precursor, AMY2B, amylase, alpha 2A; pancreatic

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:4.90 cerebellum:5.15 brain stem:4.79 corpus callosum/glia:5.16 pineal gland:- peripheral nerve:4.14 spine:4.37 retina:- eye:- artery/aorta:4.31 vein:4.11 lymphnode:5.65 peripheral blood:- spleen:5.40 thymus:5.93 bone marrow:3.78 adipose:4.54 bone:- skin:5.16
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.98 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.38 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:4.84 placenta:3.24 prostate:4.92 ovary:6.80 testis:4.50 heart:4.49 muscle:5.77 esophagus:4.29 stomach:4 intestine:8.77 colon:3.54 liver/hepato:5.40 lung:4.99 bladder:- kidney:5.11 pituitary:4.51 thyroid/parathyroid:7.67 adrenal gland:4.78 pancreas:13.37 breast:4.84 salivary:12.90
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.58 ovary:1.57 testis:0.52 heart:0.85 muscle:0.35 esophagus:- stomach:- intestine:- colon:0.39     liver/hepato:0.35        lung:1.21    bladder:- kidney:0.96 pituitary:- thyroid/parathyroid:1.27 adrenal gland:0.84 pancreas:- breast:1.16 salivary:-

Gene Information

IDs

Refseq ID NM_000699
Gene ID 279
Unigene ID -
Probe set ID 208498_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000243480
GTEx ID ENSG00000243480

Orthologous Gene

Mouse[6]  NM_001110505, NM_007446, NM_001042711, NM_001160150, NM_001160151, NM_001160152
Rat[1]  NM_001010970, NM_031502, NM_001042711, NM_001160150, NM_001160151, NM_001160152

Chromosomal Region

1p21.1  [104,159,999  -  104,262,523]

Gene Family (Interpro ID)

IPR006048  Alpha-amylase, C-terminal all beta
IPR006046  Glycoside hydrolase family 13
IPR017853  Glycoside hydrolase, catalytic core
IPR013781  Glycoside hydrolase, subgroup, catalytic core
IPR013780  Glycosyl hydrolase, family 13, all-beta
IPR006047  Glycosyl hydrolase, family 13, catalytic domain
IPR006589  Glycosyl hydrolase, family 13, subfamily, catalytic domain

Link to Pubmed  (Pubmed ID)

890964
1284286
2081604
2423416
2450054
2452973
2458567
2788608
3260028
6336237
6608795
6610603
8125298
8193143
8528071
10091666
10769135
11376382
11772019
11914097
12477932
14718574
15286789
15304511
15489334
15571103
15648851
16152770
19001184
20428766
21366335
21827821
21988832
22063648
22584580
23602568

Gene Ontology  (GO ID)

Biological Process

GO:0016052  carbohydrate catabolic process
GO:0005975  carbohydrate metabolic process
GO:0044245  polysaccharide digestion

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0004556  alpha-amylase activity
GO:0005509  calcium ion binding
GO:0031404  chloride ion binding