guanine nucleotide binding protein-like 1

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Synonym

HSR1, Guanine nucleotide-binding protein-like 1, GTP-binding protein HSR1, GNL1, guanine nucleotide binding protein-like 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:66.40 cerebellum:100.80 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:336.90 retina:- eye:52.90 artery/aorta:89.90 vein:- lymphnode:30.30 peripheral blood:18.20 spleen:132.30 thymus:335 bone marrow:- adipose:40.30 bone:89.60 skin:67.20
GeneChip cerebrum:6.91 cerebellum:7.35 brain stem:6.77 corpus callosum/glia:7.14 pineal gland:- peripheral nerve:6.83 spine:6.71 retina:- eye:- artery/aorta:7.10 vein:7.41 lymphnode:7.32 peripheral blood:- spleen:7.05 thymus:7.23 bone marrow:7.06 adipose:7.01 bone:- skin:6.93
CAGE cerebrum:3.84 cerebellum:- brain stem:3.62 corpus callosum/glia:3.60 pineal gland:3.85 peripheral nerve:- spine:3.80 retina:- eye:- artery/aorta:3.77 vein:3.39 lymphnode:3.29 peripheral blood:- spleen:3.12 thymus:3.45 bone marrow:- adipose:2.95 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:87.40 prostate:67.60 ovary:37.30 testis:216.30 heart:51.10 muscle:- esophagus:- stomach:21.20 intestine:64.80 colon:59.40     liver/hepato:21.10        lung:68.40    bladder:502.40 kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:55.80 salivary:-
GeneChip uterus:7.25 placenta:6.90 prostate:6.67 ovary:7.28 testis:7.22 heart:7.15 muscle:6.84 esophagus:7.17 stomach:7.08 intestine:7.12 colon:7.08 liver/hepato:7.10 lung:7.25 bladder:- kidney:7.07 pituitary:7.01 thyroid/parathyroid:7.44 adrenal gland:7.26 pancreas:7.27 breast:7.12 salivary:7.12
CAGE uterus:3.55 placenta:3.08 prostate:3.24 ovary:3.67 testis:4.60 heart:2.93 muscle:2.66 esophagus:3.08 stomach:- intestine:2.76 colon:3.19     liver/hepato:2.97    lung:3.46 bladder:3.14 kidney:2.98 pituitary:3.59 thyroid/parathyroid:3.63 adrenal gland:- pancreas:3.63 breast:3.66 salivary:3.64
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_005275
Gene ID 2794
Unigene ID Hs.83147
Probe set ID 203307_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204590
ENSG00000228581
ENSG00000232143
GTEx ID ENSG00000204590
ENSG00000228581
ENSG00000232143

Orthologous Gene

Mouse[2]  NM_008136
Rat[1]  NM_212500

Chromosomal Region

HSCHR6_MHC_APD  [30,517,400  -  30,529,581]
HSCHR6_MHC_MANN  [30,553,829  -  30,569,683]
HSCHR6_MHC_SSTO  [30,500,573  -  30,516,426]
HSCHR6_MHC_MCF  [30,587,611  -  30,603,465]
6p21.33  [30,509,154  -  30,525,008]
HSCHR6_MHC_DBB  [30,499,388  -  30,515,243]
HSCHR6_MHC_COX  [30,498,998  -  30,514,853]
HSCHR6_MHC_QBL  [30,498,660  -  30,514,515]

Gene Family (Interpro ID)

IPR002917  GTP-binding protein, HSR1-related
IPR006073  GTP1/OBG

Link to Pubmed  (Pubmed ID)

8180467
8889548
12477932
14702039
16341674
16344560
16702430
17525332
18255255
19851445
19912639
20360068
21139048
21890473
22145905
22244851
22863883
22939629
23000965
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006184  GTP catabolic process
GO:0006974  response to DNA damage stimulus
GO:0042254  ribosome biogenesis
GO:0007165  signal transduction
GO:0002456  T cell mediated immunity

Cellular Component

GO:0005829  cytosol
GO:0005615  extracellular space

Molecular Function

GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0005198  structural molecule activity