amylase, alpha 2B (pancreatic)

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Synonym

AMY2, AMY2B, Alpha-amylase carcinoid, Alpha-amylase 2B precursor, amylase, alpha 2B (pancreatic)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:32 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:77.30 bone marrow:19.70 adipose:80.70 bone:- skin:91.20
GeneChip cerebrum:4.90 cerebellum:5.15 brain stem:4.79 corpus callosum/glia:5.16 pineal gland:- peripheral nerve:4.14 spine:4.37 retina:- eye:- artery/aorta:4.31 vein:4.11 lymphnode:5.65 peripheral blood:- spleen:5.40 thymus:5.93 bone marrow:3.78 adipose:4.54 bone:- skin:5.16
CAGE cerebrum:0.02 cerebellum:- brain stem:0.16 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.18 vein:0.18 lymphnode:0.23 peripheral blood:- spleen:0.25 thymus:0 bone marrow:- adipose:0.90 bone:- skin:-
RNA-seq cerebrum:2.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.56 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.64 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:25.50 prostate:33.80 ovary:- testis:30.30 heart:25.50 muscle:40.20 esophagus:- stomach:- intestine:- colon:-     liver/hepato:274.40        lung:44    bladder:251.20 kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:4943.50 breast:37.20 salivary:42364.50
GeneChip uterus:4.84 placenta:3.24 prostate:4.92 ovary:6.80 testis:4.50 heart:4.49 muscle:5.77 esophagus:4.29 stomach:4 intestine:8.77 colon:3.54 liver/hepato:5.40 lung:4.99 bladder:- kidney:5.11 pituitary:4.51 thyroid/parathyroid:7.67 adrenal gland:4.78 pancreas:13.37 breast:4.84 salivary:12.90
CAGE uterus:0.11 placenta:0.08 prostate:0.21 ovary:0.14 testis:0.04 heart:0.23 muscle:0.72 esophagus:0 stomach:- intestine:0.14 colon:0.08     liver/hepato:0.36    lung:0.21 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0.32 adrenal gland:- pancreas:2.08 breast:0 salivary:3.90
RNA-seq uterus:- placenta:- prostate:1.98 ovary:2.82 testis:1.14 heart:2.09 muscle:1.40 esophagus:- stomach:- intestine:- colon:1.15     liver/hepato:1.23        lung:2.36    bladder:- kidney:2.77 pituitary:- thyroid/parathyroid:2.97 adrenal gland:2.45 pancreas:- breast:2.97 salivary:-

Gene Information

IDs

Refseq ID NM_020978
Gene ID 280
Unigene ID Hs.484588
Probe set ID 208498_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000240038
GTEx ID ENSG00000240038

Orthologous Gene

Mouse[6]  NM_001110505, NM_007446, NM_001042711, NM_001160150, NM_001160151, NM_001160152
Rat[1]  NM_001010970, NM_031502, NM_001042711, NM_001160150, NM_001160151, NM_001160152

Chromosomal Region

1p21.1  [104,096,437  -  104,122,156]

Gene Family (Interpro ID)

IPR006048  Alpha-amylase, C-terminal all beta
IPR006046  Glycoside hydrolase family 13
IPR017853  Glycoside hydrolase, catalytic core
IPR013781  Glycoside hydrolase, subgroup, catalytic core
IPR013780  Glycosyl hydrolase, family 13, all-beta
IPR006047  Glycosyl hydrolase, family 13, catalytic domain
IPR006589  Glycosyl hydrolase, family 13, subfamily, catalytic domain

Link to Pubmed  (Pubmed ID)

309725
890964
1429515
1692298
2081604
2401405
2452973
2458567
2483397
2701942
2788608
3260028
6608795
8268204
11347906
11376382
11408008
12477932
14702039
15252450
15286789
15489334
16152770
16344560
24244333

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0007586  digestion

Cellular Component

GO:0005576  extracellular region

Molecular Function

GO:0004556  alpha-amylase activity
GO:0046872  metal ion binding