glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)

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Synonym

GIG18, Transaminase A, Aspartate aminotransferase, cytoplasmic, Glutamate oxaloacetate transaminase 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:330.70 cerebellum:667.50 brain stem:- corpus callosum/glia:204.10 pineal gland:296.70 peripheral nerve:30.70 spine:112.30 retina:118.60 eye:117.50 artery/aorta:30 vein:- lymphnode:111.20 peripheral blood:54.70 spleen:18.90 thymus:38.70 bone marrow:59 adipose:564.70 bone:51.20 skin:192
GeneChip cerebrum:8.42 cerebellum:8.28 brain stem:8.63 corpus callosum/glia:6.93 pineal gland:- peripheral nerve:7.85 spine:7.34 retina:- eye:- artery/aorta:6.51 vein:7.39 lymphnode:6.26 peripheral blood:- spleen:6.15 thymus:6.08 bone marrow:5.88 adipose:6.47 bone:- skin:7.28
CAGE cerebrum:4.50 cerebellum:- brain stem:4.38 corpus callosum/glia:4.08 pineal gland:4.09 peripheral nerve:- spine:3.21 retina:- eye:- artery/aorta:2.59 vein:2.91 lymphnode:3.04 peripheral blood:- spleen:3.00 thymus:2.91 bone marrow:- adipose:2.55 bone:- skin:-
RNA-seq cerebrum:6.54 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.93 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.78 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:80.10 prostate:123.90 ovary:74.50 testis:108.20 heart:753.50 muscle:381.70 esophagus:- stomach:148.70 intestine:194.40 colon:50.90     liver/hepato:147.80        lung:88    bladder:251.20 kidney:280.70 pituitary:- thyroid/parathyroid:982.50 adrenal gland:50.80 pancreas:44.50 breast:37.20 salivary:328.40
GeneChip uterus:6.24 placenta:6.06 prostate:6.99 ovary:6.30 testis:8.15 heart:9.04 muscle:9.81 esophagus:8.34 stomach:7.16 intestine:7.67 colon:7.58 liver/hepato:9.32 lung:5.83 bladder:- kidney:8.81 pituitary:6.34 thyroid/parathyroid:6.54 adrenal gland:7.44 pancreas:7.16 breast:6.55 salivary:7.67
CAGE uterus:2.86 placenta:2.94 prostate:2.88 ovary:3.19 testis:4.20 heart:4.94 muscle:5.18 esophagus:3.75 stomach:- intestine:4.31 colon:3.87     liver/hepato:5.98    lung:2.66 bladder:3.12 kidney:5.26 pituitary:3.21 thyroid/parathyroid:3.62 adrenal gland:- pancreas:3.06 breast:2.34 salivary:4.49
RNA-seq uterus:- placenta:- prostate:3.64 ovary:3.72 testis:4.87 heart:7.34 muscle:5.94 esophagus:- stomach:- intestine:- colon:3.57     liver/hepato:6.72        lung:3.29    bladder:- kidney:6.68 pituitary:- thyroid/parathyroid:4.89 adrenal gland:3.06 pancreas:- breast:3.13 salivary:-

Gene Information

IDs

Refseq ID NM_002079
Gene ID 2805
Unigene ID Hs.500756
Probe set ID 208813_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000120053
GTEx ID ENSG00000120053

Orthologous Gene

Mouse[1]  NM_010324
Rat [0]  

Chromosomal Region

10q24.2  [101,156,627  -  101,190,393]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

225064
1974457
2182221
2225456
2241899
2731362
2777255
3207426
6391741
6397370
7060339
8349677
8396422
8619474
9110174
10360399
12477932
12480555
15164054
15306699
15489334
16169070
16344560
16681433
17623298
17877759
17907318
18242760
18752324
19012630
19056867
19370784
19393479
20029029
20201926
20205615
20499337
20972737
21139048
21750724
21900944
21906983
21963094
21988832
22132177
22242166
22352690
22412388
22863883
23667618
24124411
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0006532  aspartate biosynthetic process
GO:0006533  aspartate catabolic process
GO:0006531  aspartate metabolic process
GO:0005975  carbohydrate metabolic process
GO:0008652  cellular amino acid biosynthetic process
GO:0034641  cellular nitrogen compound metabolic process
GO:0032869  cellular response to insulin stimulus
GO:0055089  fatty acid homeostasis
GO:0006094  gluconeogenesis
GO:0006006  glucose metabolic process
GO:0019551  glutamate catabolic process to 2-oxoglutarate
GO:0019550  glutamate catabolic process to aspartate
GO:0006536  glutamate metabolic process
GO:0006114  glycerol biosynthetic process
GO:0019509  L-methionine salvage from methylthioadenosine
GO:0006107  oxaloacetate metabolic process
GO:0006595  polyamine metabolic process
GO:0051384  response to glucocorticoid stimulus
GO:0000096  sulfur amino acid metabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005764  lysosome
GO:0043679  nerve terminal

Molecular Function

GO:0031406  carboxylic acid binding
GO:0004069  L-aspartate:2-oxoglutarate aminotransferase activity
GO:0047801  L-cysteine:2-oxoglutarate aminotransferase activity
GO:0080130  L-phenylalanine:2-oxoglutarate aminotransferase activity
GO:0004609  phosphatidylserine decarboxylase activity
GO:0030170  pyridoxal phosphate binding
GO:0008483  transaminase activity