glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

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Synonym

FLJ40994, GOT2, Glutamate oxaloacetate transaminase 2, Transaminase A

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:410.10 cerebellum:705.30 brain stem:- corpus callosum/glia:816.50 pineal gland:- peripheral nerve:92 spine:224.60 retina:- eye:176.30 artery/aorta:599.50 vein:266.60 lymphnode:202.20 peripheral blood:145.70 spleen:472.70 thymus:167.50 bone marrow:19.70 adipose:1169.70 bone:115.20 skin:230.40
GeneChip cerebrum:8.92 cerebellum:9.10 brain stem:9.02 corpus callosum/glia:8.32 pineal gland:- peripheral nerve:9.19 spine:8.42 retina:- eye:- artery/aorta:8.05 vein:8.58 lymphnode:8.04 peripheral blood:- spleen:7.89 thymus:8.03 bone marrow:7.68 adipose:7.50 bone:- skin:8.35
CAGE cerebrum:4.63 cerebellum:- brain stem:4.74 corpus callosum/glia:4.65 pineal gland:4.67 peripheral nerve:- spine:4.20 retina:- eye:- artery/aorta:3.64 vein:3.81 lymphnode:4.35 peripheral blood:- spleen:3.88 thymus:4.08 bone marrow:- adipose:3.76 bone:- skin:-
RNA-seq cerebrum:5.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.54 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.23 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:182.30 placenta:127.50 prostate:360.50 ovary:37.30 testis:216.30 heart:459.80 muscle:221 esophagus:342.80 stomach:127.50 intestine:356.40 colon:186.60     liver/hepato:316.70        lung:195.50    bladder:628.10 kidney:270.30 pituitary:116 thyroid/parathyroid:655 adrenal gland:355.50 pancreas:35.60 breast:102.20 salivary:-
GeneChip uterus:8.08 placenta:7.39 prostate:9.08 ovary:8.33 testis:8.45 heart:9.70 muscle:11.05 esophagus:9.25 stomach:8.45 intestine:8.97 colon:8.77 liver/hepato:10.52 lung:7.77 bladder:- kidney:9.28 pituitary:8.60 thyroid/parathyroid:8.38 adrenal gland:8.79 pancreas:8.05 breast:8.31 salivary:8.59
CAGE uterus:3.90 placenta:3.52 prostate:4.15 ovary:3.98 testis:4.40 heart:5.54 muscle:5.68 esophagus:4.50 stomach:- intestine:4.00 colon:4.21     liver/hepato:5.55    lung:3.91 bladder:4.17 kidney:4.73 pituitary:4.10 thyroid/parathyroid:4.25 adrenal gland:- pancreas:4.01 breast:3.90 salivary:4.59
RNA-seq uterus:- placenta:- prostate:5.49 ovary:5.00 testis:4.89 heart:7.38 muscle:6.36 esophagus:- stomach:- intestine:- colon:4.64     liver/hepato:6.52        lung:4.25    bladder:- kidney:5.88 pituitary:- thyroid/parathyroid:5.59 adrenal gland:4.71 pancreas:- breast:3.94 salivary:-

Gene Information

IDs

Refseq ID NM_002080
Gene ID 2806
Unigene ID Hs.599470
Probe set ID 200708_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125166
GTEx ID ENSG00000125166

Orthologous Gene

Mouse[2]  NM_010325
Rat [0]  

Chromosomal Region

16q21  [58,741,035  -  58,768,239]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

376500
752471
2182221
2567216
2731362
2777255
2899080
3207426
3997814
4052435
5450376
6397370
6930651
7114792
7225087
7559589
8125298
8349677
9537447
12477932
12601813
14702039
15489334
16169070
16212419
17353931
17442055
17728674
17877759
18781797
19305408
19834535
20360068
20877624
21081666
21139048
21223598
21319273
21890473
21900206
21906983
21963094
22713574
23000965
24583282
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0019470  4-hydroxyproline catabolic process
GO:0006532  aspartate biosynthetic process
GO:0006533  aspartate catabolic process
GO:0006531  aspartate metabolic process
GO:0005975  carbohydrate metabolic process
GO:0008652  cellular amino acid biosynthetic process
GO:0034641  cellular nitrogen compound metabolic process
GO:0015908  fatty acid transport
GO:0006094  gluconeogenesis
GO:0006006  glucose metabolic process
GO:0019551  glutamate catabolic process to 2-oxoglutarate
GO:0019550  glutamate catabolic process to aspartate
GO:0006536  glutamate metabolic process
GO:0006107  oxaloacetate metabolic process
GO:0045471  response to ethanol

Cellular Component

GO:0005743  mitochondrial inner membrane
GO:0005759  mitochondrial matrix
GO:0005739  mitochondrion
GO:0005886  plasma membrane

Molecular Function

GO:0016212  kynurenine-oxoglutarate transaminase activity
GO:0004069  L-aspartate:2-oxoglutarate aminotransferase activity
GO:0080130  L-phenylalanine:2-oxoglutarate aminotransferase activity
GO:0030170  pyridoxal phosphate binding