SH3 and PX domains 2B

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Synonym

SH3PXD2B, SH3 and PX domains 2B, FLJ20831, KIAA1295

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:112.30 retina:118.60 eye:52.90 artery/aorta:- vein:66.60 lymphnode:- peripheral blood:- spleen:- thymus:38.70 bone marrow:- adipose:40.30 bone:38.40 skin:81.60
GeneChip nodata
CAGE cerebrum:3.00 cerebellum:- brain stem:3.56 corpus callosum/glia:3.87 pineal gland:2.74 peripheral nerve:- spine:3.51 retina:- eye:- artery/aorta:3.67 vein:3.30 lymphnode:3.00 peripheral blood:- spleen:3.12 thymus:1.92 bone marrow:- adipose:4.34 bone:- skin:-
RNA-seq cerebrum:2.71 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.84 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.13 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:109.40 placenta:18.20 prostate:56.30 ovary:37.30 testis:43.30 heart:38.30 muscle:- esophagus:- stomach:21.20 intestine:- colon:67.80     liver/hepato:31.70        lung:34.20    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:158 salivary:-
GeneChip nodata
CAGE uterus:3.93 placenta:3.12 prostate:3.48 ovary:3.91 testis:3.41 heart:3.08 muscle:2.52 esophagus:3.27 stomach:- intestine:2.67 colon:3.44     liver/hepato:1.71    lung:3.55 bladder:3.86 kidney:2.26 pituitary:2.11 thyroid/parathyroid:2.26 adrenal gland:- pancreas:2.66 breast:4.44 salivary:2.93
RNA-seq uterus:- placenta:- prostate:2.99 ovary:3.74 testis:2.98 heart:1.59 muscle:0.84 esophagus:- stomach:- intestine:- colon:2.66     liver/hepato:0.82        lung:2.60    bladder:- kidney:1.51 pituitary:- thyroid/parathyroid:2.42 adrenal gland:2.44 pancreas:- breast:2.37 salivary:-

Gene Information

IDs

Refseq ID NM_001017995
Gene ID 285590
Unigene ID Hs.285666
Probe set ID -
Ensembl ID ENSG00000174705
GTEx ID ENSG00000174705

Orthologous Gene

Mouse[1]  NM_177364
Rat[1]  NM_177364

Chromosomal Region

5q35.1  [171,752,185  -  171,881,527]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10718198
11181995
12477932
14702039
18959745
19144821
19228371
19531213
19755710
19807924
20137777
20379614
20609497
20943948
21139048
21706016
21886807
21890473
22829589
22939629
23000965
23383108

Gene Ontology  (GO ID)

Biological Process

GO:0060612  adipose tissue development
GO:0060348  bone development
GO:0007154  cell communication
GO:0030154  cell differentiation
GO:0022617  extracellular matrix disassembly
GO:0001654  eye development
GO:0007507  heart development
GO:0045600  positive regulation of fat cell differentiation
GO:0001501  skeletal system development
GO:0006801  superoxide metabolic process

Cellular Component

GO:0030054  cell junction
GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0002102  podosome

Molecular Function

GO:0032266  phosphatidylinositol 3-phosphate binding
GO:0080025  phosphatidylinositol-3,5-bisphosphate binding
GO:0070273  phosphatidylinositol-4-phosphate binding
GO:0010314  phosphatidylinositol-5-phosphate binding
GO:0005515  protein binding
GO:0042169  SH2 domain binding