ankyrin 3, node of Ranvier (ankyrin G)

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Synonym

Ankyrin-3, ankyrin 3, node of Ranvier (ankyrin G), Ankyrin-G, ANK-3, FLJ45464, ANK3, ANKYRIN-G

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:161.20 cerebellum:151.10 brain stem:- corpus callosum/glia:116.60 pineal gland:148.30 peripheral nerve:61.30 spine:112.30 retina:237.30 eye:111.70 artery/aorta:- vein:- lymphnode:30.30 peripheral blood:36.40 spleen:18.90 thymus:12.90 bone marrow:39.40 adipose:- bone:25.60 skin:57.60
GeneChip cerebrum:8.68 cerebellum:9.03 brain stem:8.77 corpus callosum/glia:8.47 pineal gland:- peripheral nerve:8.53 spine:7.39 retina:- eye:- artery/aorta:7.01 vein:6.03 lymphnode:6.15 peripheral blood:- spleen:6.69 thymus:5.31 bone marrow:5.07 adipose:5.74 bone:- skin:6.52
CAGE cerebrum:5.30 cerebellum:- brain stem:5.31 corpus callosum/glia:5.10 pineal gland:4.02 peripheral nerve:- spine:4.72 retina:- eye:- artery/aorta:3.00 vein:2.90 lymphnode:2.99 peripheral blood:- spleen:3.28 thymus:2.23 bone marrow:- adipose:2.10 bone:- skin:-
RNA-seq cerebrum:3.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.04 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.02 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:316.90 prostate:112.60 ovary:74.50 testis:30.30 heart:166 muscle:60.30 esophagus:- stomach:- intestine:- colon:59.40     liver/hepato:31.70        lung:92.90    bladder:- kidney:166.40 pituitary:232 thyroid/parathyroid:327.50 adrenal gland:- pancreas:17.80 breast:148.70 salivary:-
GeneChip uterus:6.48 placenta:9.02 prostate:7.39 ovary:6.47 testis:5.73 heart:7.56 muscle:7.01 esophagus:6.97 stomach:6.60 intestine:6.36 colon:6.41 liver/hepato:6.53 lung:6.16 bladder:- kidney:8.34 pituitary:7.33 thyroid/parathyroid:7.75 adrenal gland:6.08 pancreas:5.97 breast:6.40 salivary:7.54
CAGE uterus:3.18 placenta:5.36 prostate:3.34 ovary:2.62 testis:2.47 heart:4.19 muscle:3.70 esophagus:3.28 stomach:- intestine:4.23 colon:3.80     liver/hepato:2.54    lung:3.71 bladder:2.87 kidney:4.90 pituitary:4.05 thyroid/parathyroid:3.31 adrenal gland:- pancreas:3.10 breast:1.68 salivary:3.35
RNA-seq uterus:- placenta:- prostate:0.08 ovary:0.02 testis:0.34 heart:0.32 muscle:0.07 esophagus:- stomach:- intestine:- colon:0.10     liver/hepato:0.02        lung:0.01    bladder:- kidney:0.21 pituitary:- thyroid/parathyroid:0.23 adrenal gland:0.03 pancreas:- breast:0.02 salivary:-

Gene Information

IDs

Refseq ID NM_020987
Gene ID 288
Unigene ID Hs.499725
Probe set ID 209442_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000151150
GTEx ID ENSG00000151150

Orthologous Gene

Mouse[25]  NM_009670, NM_146005, NM_170687, NM_170688, NM_170689, NM_170690, NM_170728, NM_170729, NM_170730
Rat[6]  NM_031805, NM_146005, NM_170687, NM_170688, NM_170689, NM_170690, NM_170728, NM_170729, NM_170730

Chromosomal Region

10q21.2  [61,788,159  -  62,493,248]

Gene Family (Interpro ID)

IPR000488  Death
IPR011029  DEATH-like

Link to Pubmed  (Pubmed ID)

7665168
7836469
8666667
10893266
10907644
11781319
11807096
11950515
11997395
12036953
12507143
12805291
14694156
14702039
14757759
14761957
15231748
15342556
15611082
15823567
15931389
16377635
16385451
16775201
17033732
17074766
17370265
17373700
17620337
18163421
18180363
18635543
18711365
18768923
19088739
20185149
20351715
20379614
20386566
20636642
20877300
20936779
21037240
21139048
21304963
21395576
21438140
21676128
21702894
21767209
21893642
21926972
21926974
21972176
22118674
22180603
22182935
22328486
22498896
22647524
22688190
22688191
22850628
22865819
22986903
23109352
23129772
23390136
23453885
23715300
23796624
23898208
24108394
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0007409  axonogenesis
GO:0000281  cytokinesis after mitosis
GO:0045184  establishment of protein localization
GO:0043001  Golgi to plasma membrane protein transport
GO:0007009  plasma membrane organization
GO:0010628  positive regulation of gene expression
GO:0045838  positive regulation of membrane potential
GO:0010765  positive regulation of sodium ion transport
GO:0019228  regulation of action potential in neuron
GO:0043266  regulation of potassium ion transport
GO:0007165  signal transduction
GO:0050808  synapse organization

Cellular Component

GO:0009925  basal plasma membrane
GO:0016323  basolateral plasma membrane
GO:0009986  cell surface
GO:0043034  costamere
GO:0043194  initial segment
GO:0014704  intercalated disc
GO:0016328  lateral plasma membrane
GO:0005764  lysosome
GO:0033268  node of Ranvier
GO:0033270  paranode region of axon
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0042383  sarcolemma
GO:0014731  spectrin-associated cytoskeleton
GO:0030315  T-tubule
GO:0005923  tight junction

Molecular Function

GO:0045296  cadherin binding
GO:0008092  cytoskeletal protein binding
GO:0005515  protein binding
GO:0030674  protein binding, bridging
GO:0030507  spectrin binding
GO:0005200  structural constituent of cytoskeleton