glutamate receptor, ionotropic, AMPA 2

 jump to detail

Synonym

GluR-B, glutamate receptor, ionotropic, AMPA 2, HBGR2, GluR-2, Glutamate receptor 2 precursor, AMPA-selective glutamate receptor 2, GluR-K2, GRIA2, Glutamate receptor ionotropic, AMPA 2, GLUR2, GLURB

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.10 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:- spine:- retina:- eye:70.50 artery/aorta:- vein:- lymphnode:91 peripheral blood:182.20 spleen:18.90 thymus:38.70 bone marrow:19.70 adipose:- bone:- skin:33.60
GeneChip cerebrum:9.84 cerebellum:9.84 brain stem:8.53 corpus callosum/glia:8.93 pineal gland:- peripheral nerve:6.98 spine:8.13 retina:- eye:- artery/aorta:5.36 vein:4.02 lymphnode:3.94 peripheral blood:- spleen:3.43 thymus:3.58 bone marrow:3.79 adipose:3.56 bone:- skin:3.99
CAGE cerebrum:5.02 cerebellum:- brain stem:3.79 corpus callosum/glia:3.75 pineal gland:3.53 peripheral nerve:- spine:3.79 retina:- eye:- artery/aorta:2.93 vein:0.34 lymphnode:0.30 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0.36 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:105.60 prostate:67.60 ovary:74.50 testis:30.30 heart:89.40 muscle:- esophagus:- stomach:42.50 intestine:- colon:25.40     liver/hepato:31.70        lung:19.60    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:327.50 adrenal gland:- pancreas:142.30 breast:92.90 salivary:656.80
GeneChip uterus:5.27 placenta:3.51 prostate:3.84 ovary:5.22 testis:3.91 heart:3.71 muscle:3.97 esophagus:3.87 stomach:4.41 intestine:3.50 colon:3.70 liver/hepato:3.69 lung:3.46 bladder:- kidney:3.57 pituitary:8.80 thyroid/parathyroid:3.56 adrenal gland:4.32 pancreas:3.73 breast:4.67 salivary:4.07
CAGE uterus:2.25 placenta:0 prostate:0.21 ovary:1.27 testis:0.44 heart:0.16 muscle:0.25 esophagus:0.26 stomach:- intestine:0 colon:0.15     liver/hepato:0    lung:0.22 bladder:0.09 kidney:0.15 pituitary:4.10 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.48 testis:0.15 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.08     liver/hepato:0        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_000826
Gene ID 2891
Unigene ID Hs.327631
Probe set ID 205358_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000120251
GTEx ID ENSG00000120251

Orthologous Gene

Mouse[3]  NM_001039195, NM_001083806, NM_013540
Rat[4]  NM_001083811, NM_017261, NM_013540

Chromosomal Region

4q32.1  [158,125,334  -  158,287,227]

Gene Family (Interpro ID)

IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

1311100
1319477
1699275
1717158
7523595
7545935
7919190
8003671
8269514
8288598
8420792
8848293
9481670
9648857
9697855
9768844
10027300
10358037
10501226
10576550
10688364
10985351
11007883
11086992
11140673
11466413
11860506
11891216
11931740
12058067
12062022
12125045
12130635
12477932
12573530
12694394
12805550
12859334
14630051
14687553
14730302
14985749
15006707
15071096
15144856
15145077
15342556
15489334
15858065
16045445
16055064
16215279
16344560
16724110
16990550
17409242
17942280
18163426
18311135
18403631
18976975
19004011
19086053
19102704
19156168
19448189
19558602
19651138
19933774
20347265
20398908
20409611
20468064
21173224
21221849
21383172
21397006
21843653
21856433
21948504
21988832
22057216
22094384
22122651
22366356
22644307
23475111
23595422
23613500
24550387
24623784
24652293
24749734

Gene Ontology  (GO ID)

Biological Process

GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0007165  signal transduction
GO:0007268  synaptic transmission

Cellular Component

GO:0032281  alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0030054  cell junction
GO:0030666  endocytic vesicle membrane
GO:0005789  endoplasmic reticulum membrane
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0008021  synaptic vesicle

Molecular Function

GO:0004971  alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0008066  glutamate receptor activity
GO:0004970  ionotropic glutamate receptor activity
GO:0015277  kainate selective glutamate receptor activity