transmembrane protease, serine 11E

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Synonym

TMPRSS11E, MGC141972, transmembrane protease, serine 11E, DESC1, UNQ742/PRO1461, Serine protease DESC1, Transmembrane protease, serine 11E precursor, MGC141974

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:3.75 cerebellum:3.70 brain stem:3.80 corpus callosum/glia:3.75 pineal gland:- peripheral nerve:3.84 spine:3.71 retina:- eye:- artery/aorta:3.83 vein:3.86 lymphnode:4.95 peripheral blood:- spleen:3.74 thymus:3.83 bone marrow:3.83 adipose:4.18 bone:- skin:5.20
CAGE cerebrum:0.01 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:2.30 peripheral blood:- spleen:0 thymus:0.23 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.06 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.05 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:- salivary:-
GeneChip uterus:4.41 placenta:3.72 prostate:4.18 ovary:3.67 testis:3.70 heart:3.84 muscle:4.09 esophagus:9.78 stomach:3.78 intestine:3.89 colon:3.83 liver/hepato:3.95 lung:3.79 bladder:- kidney:3.87 pituitary:3.89 thyroid/parathyroid:3.77 adrenal gland:3.74 pancreas:4.25 breast:4.08 salivary:4.41
CAGE uterus:2.92 placenta:0.54 prostate:1.59 ovary:0 testis:0.24 heart:0 muscle:0 esophagus:5.58 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0.05 bladder:1.64 kidney:0.08 pituitary:0.26 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:2.99
RNA-seq uterus:- placenta:- prostate:1.55 ovary:0 testis:0.80 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0.01    bladder:- kidney:0.19 pituitary:- thyroid/parathyroid:0.06 adrenal gland:0.10 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_014058
Gene ID 28983
Unigene ID Hs.201877
Probe set ID 220431_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000087128
GTEx ID ENSG00000087128

Orthologous Gene

Mouse[1]  NM_172880
Rat[1]  NM_172880

Chromosomal Region

4q13.2  [69,313,167  -  69,363,322]

Gene Family (Interpro ID)

IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR009003  Serine/cysteine peptidase, trypsin-like

Link to Pubmed  (Pubmed ID)

9847074
11161383
12477932
12975309
15328353
15489334
15815621
16344560
17388811

Gene Ontology  (GO ID)

Biological Process

GO:0006508  proteolysis

Cellular Component

GO:0005576  extracellular region
GO:0005887  integral to plasma membrane

Molecular Function

GO:0004252  serine-type endopeptidase activity
GO:0008236  serine-type peptidase activity