chromosome 13 open reading frame 15

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Synonym

response gene to complement 32, bA157L14.2, KIAA0564, MGC87338, RGC32

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:61.60 cerebellum:- brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:224.60 retina:- eye:17.60 artery/aorta:- vein:- lymphnode:50.60 peripheral blood:127.50 spleen:37.80 thymus:12.90 bone marrow:177.10 adipose:- bone:51.20 skin:14.40
GeneChip cerebrum:8.91 cerebellum:8.68 brain stem:9.04 corpus callosum/glia:9.83 pineal gland:- peripheral nerve:9.40 spine:8.77 retina:- eye:- artery/aorta:7.96 vein:8.36 lymphnode:7.32 peripheral blood:- spleen:6.57 thymus:8.86 bone marrow:9.29 adipose:9.22 bone:- skin:7.87
CAGE cerebrum:4.66 cerebellum:- brain stem:4.82 corpus callosum/glia:5.07 pineal gland:3.11 peripheral nerve:- spine:4.40 retina:- eye:- artery/aorta:3.76 vein:3.83 lymphnode:3.21 peripheral blood:- spleen:3.15 thymus:4.06 bone marrow:- adipose:4.66 bone:- skin:-
RNA-seq cerebrum:4.83 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.29 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.41 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:98.40 prostate:45.10 ovary:- testis:30.30 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:21.10        lung:190.60    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:97.80 breast:27.90 salivary:-
GeneChip uterus:6.90 placenta:9.96 prostate:7.58 ovary:6.32 testis:7.61 heart:8.70 muscle:6.95 esophagus:6.76 stomach:7.15 intestine:7.37 colon:6.74 liver/hepato:4.09 lung:11.23 bladder:- kidney:7.74 pituitary:6.75 thyroid/parathyroid:9.13 adrenal gland:7.18 pancreas:6.51 breast:7.80 salivary:9.36
CAGE uterus:3.20 placenta:5.64 prostate:3.74 ovary:2.38 testis:1.97 heart:3.93 muscle:3.64 esophagus:3.27 stomach:- intestine:2.53 colon:2.90     liver/hepato:1.74    lung:5.68 bladder:3.77 kidney:3.28 pituitary:2.32 thyroid/parathyroid:3.71 adrenal gland:- pancreas:3.02 breast:4.83 salivary:4.60
RNA-seq uterus:- placenta:- prostate:4.35 ovary:2.03 testis:4.02 heart:5.29 muscle:3.02 esophagus:- stomach:- intestine:- colon:5.62     liver/hepato:0.75        lung:8.66    bladder:- kidney:4.42 pituitary:- thyroid/parathyroid:4.68 adrenal gland:3.51 pancreas:- breast:5.31 salivary:-

Gene Information

IDs

Refseq ID NM_014059
Gene ID 28984
Unigene ID Hs.507866
Probe set ID 218723_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000102760
GTEx ID ENSG00000102760

Orthologous Gene

Mouse[2]  NM_025427
Rat[2]  NM_025427

Chromosomal Region

13q14.11  [42,031,695  -  42,045,018]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
9756947
11687586
12477932
14702039
15057823
15489334
15591621
15713436
15932515
17081983
17146433
18029348
18308847
19158077
19162005
19270026
19652095
19883641
20635389
20862745
21307346
21833088
21990365
22163048
23000427
23715780
24068962

Gene Ontology  (GO ID)

Biological Process

GO:0071456  cellular response to hypoxia
GO:0006956  complement activation
GO:0016525  negative regulation of angiogenesis
GO:0043537  negative regulation of blood vessel endothelial cell migration
GO:0008285  negative regulation of cell proliferation
GO:0050710  negative regulation of cytokine secretion
GO:0001937  negative regulation of endothelial cell proliferation
GO:0001100  negative regulation of exit from mitosis
GO:0071158  positive regulation of cell cycle arrest
GO:0032967  positive regulation of collagen biosynthetic process
GO:0031659  positive regulation of cyclin-dependent protein kinase activity during G1/S
GO:0050715  positive regulation of cytokine secretion
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0003331  positive regulation of extracellular matrix constituent secretion
GO:0045840  positive regulation of mitosis
GO:0051496  positive regulation of stress fiber formation
GO:0051091  positive regulation of transcription factor activity

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0030295  protein kinase activator activity
GO:0019901  protein kinase binding
GO:0070412  R-SMAD binding