glutamate receptor, ionotropic, N-methyl D-aspartate 1

Synonym

NR1, N-methyl-D-aspartate receptor subunit NR1, GRIN1, NMDA1, Glutamate [NMDA] receptor subunit zeta 1 precursor, NMDAR1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:58.10

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:112.30

retina:-

eye:94

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:6.90

cerebellum:6.89

brain stem:6.83

corpus callosum/glia:6.63

pineal gland:-

peripheral nerve:6.35

spine:6.39

retina:-

eye:-

artery/aorta:6.53

vein:7.04

lymphnode:6.59

peripheral blood:-

spleen:6.30

thymus:6.32

bone marrow:6.80

adipose:6.65

bone:-

skin:6.40

CAGE

cerebrum:6.01

cerebellum:-

brain stem:3.74

corpus callosum/glia:4.05

pineal gland:0.91

peripheral nerve:-

spine:4.10

retina:-

eye:-

artery/aorta:0.69

vein:0.59

lymphnode:0.03

peripheral blood:-

spleen:0

thymus:0.06

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:3.13

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.03

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:37.30

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:17.80

breast:-

salivary:-

GeneChip

uterus:6.51

placenta:6.25

prostate:5.87

ovary:6.60

testis:6.09

heart:6.81

muscle:6.74

esophagus:6.72

stomach:6.53

intestine:6.74

colon:6.75

liver/hepato:6.86

lung:6.63

bladder:-

kidney:6.59

pituitary:6.61

thyroid/parathyroid:6.34

adrenal gland:6.75

pancreas:7.10

breast:6.35

salivary:6.75

CAGE

uterus:0.19

placenta:0.08

prostate:0.08

ovary:0.07

testis:0.29

heart:0

muscle:0

esophagus:0.26

stomach:-

intestine:0.07

colon:0.64

liver/hepato:0

lung:0

bladder:0.09

kidney:0

pituitary:0.34

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0.36

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.01

testis:0.00

heart:0

muscle:0.01

esophagus:-

stomach:-

intestine:-

colon:0.24

liver/hepato:0.01

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.05

adrenal gland:0.02

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_000832
Gene ID	2902
Unigene ID	Hs.558334
Probe set ID	210782_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000176884
GTEx ID	ENSG00000176884

Orthologous Gene

Mouse[2]	NM_001177656, NM_001177657, NM_008169
Rat [0]

Chromosomal Region

9q34.3 [140,032,842 - 140,063,207]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001320	Ionotropic glutamate receptor
IPR001508	NMDA receptor

Gene Ontology (GO ID)

Biological Process

GO:0008344	adult locomotory behavior
GO:0055074	calcium ion homeostasis
GO:0006812	cation transport
GO:0006874	cellular calcium ion homeostasis
GO:0071287	cellular response to manganese ion
GO:0021987	cerebral cortex development
GO:0001661	conditioned taste aversion
GO:0035235	ionotropic glutamate receptor signaling pathway
GO:0007616	long-term memory
GO:0060179	male mating behavior
GO:0043524	negative regulation of neuron apoptosis
GO:0008355	olfactory learning
GO:0021586	pons maturation
GO:0043065	positive regulation of apoptosis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060134	prepulse inhibition
GO:0018964	propylene metabolic process
GO:0050770	regulation of axonogenesis
GO:0048814	regulation of dendrite morphogenesis
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0042391	regulation of membrane potential
GO:0043576	regulation of respiratory gaseous exchange
GO:0051963	regulation of synaptogenesis
GO:0007585	respiratory gaseous exchange
GO:0001975	response to amphetamine
GO:0051592	response to calcium ion
GO:0045471	response to ethanol
GO:0043278	response to morphine
GO:0048511	rhythmic process
GO:0019233	sensory perception of pain
GO:0035176	social behavior
GO:0001967	suckling behavior
GO:0007268	synaptic transmission
GO:0035249	synaptic transmission, glutamatergic
GO:0008542	visual learning

Cellular Component

GO:0030054	cell junction
GO:0009986	cell surface
GO:0030425	dendrite
GO:0032590	dendrite membrane
GO:0043197	dendritic spine
GO:0060076	excitatory synapse
GO:0005887	integral to plasma membrane
GO:0017146	N-methyl-D-aspartate selective glutamate receptor complex
GO:0043005	neuron projection
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0045202	synapse
GO:0043083	synaptic cleft
GO:0008021	synaptic vesicle
GO:0043195	terminal button

Molecular Function

GO:0005262	calcium channel activity
GO:0005509	calcium ion binding
GO:0005516	calmodulin binding
GO:0019899	enzyme binding
GO:0005234	extracellular-glutamate-gated ion channel activity
GO:0016595	glutamate binding
GO:0035254	glutamate receptor binding
GO:0016594	glycine binding
GO:0004972	N-methyl-D-aspartate selective glutamate receptor activity
GO:0042165	neurotransmitter binding
GO:0005515	protein binding
GO:0022843	voltage-gated cation channel activity

glutamate receptor, ionotropic, N-methyl D-aspartate 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function