glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Synonym

hNR2A, NMDAR2A, GRIN2A, N-methyl D-aspartate receptor subtype 2A, NR2A

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:46.20 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:59 adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:2.42 cerebellum:- brain stem:0.56 corpus callosum/glia:1.49 pineal gland:0.47 peripheral nerve:- spine:0.89 retina:- eye:- artery/aorta:0.95 vein:0.79 lymphnode:0.12 peripheral blood:- spleen:0 thymus:0.18 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.14 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:- salivary:-
GeneChip nodata
CAGE uterus:0.43 placenta:0 prostate:0.33 ovary:0.52 testis:0.69 heart:0.24 muscle:0.25 esophagus:0.63 stomach:- intestine:0.21 colon:0.15     liver/hepato:0    lung:0.10 bladder:0.58 kidney:0.27 pituitary:0.10 thyroid/parathyroid:0.12 adrenal gland:- pancreas:0.58 breast:0 salivary:0.83
RNA-seq uterus:- placenta:- prostate:0 ovary:0.01 testis:0.04 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0.02 pancreas:- breast:0.00 salivary:-

IDs

Refseq ID NM_001134408
Gene ID 2903
Unigene ID Hs.411472
Probe set ID -
Ensembl ID ENSG00000183454
GTEx ID ENSG00000183454

Orthologous Gene

Mouse[1]  NM_008170
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0033058  directional locomotion
GO:0042417  dopamine metabolic process
GO:0007215  glutamate signaling pathway
GO:0007611  learning or memory
GO:0007613  memory
GO:0042177  negative regulation of protein catabolic process
GO:0022008  neurogenesis
GO:0043065  positive regulation of apoptosis
GO:0008104  protein localization
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0051930  regulation of sensory perception of pain
GO:0048167  regulation of synaptic plasticity
GO:0001975  response to amphetamine
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0009611  response to wounding
GO:0019233  sensory perception of pain
GO:0042428  serotonin metabolic process
GO:0030431  sleep
GO:0001964  startle response
GO:0007268  synaptic transmission
GO:0006810  transport
GO:0008542  visual learning

Cellular Component

GO:0030054  cell junction
GO:0009986  cell surface
GO:0005887  integral to plasma membrane
GO:0017146  N-methyl-D-aspartate selective glutamate receptor complex
GO:0043005  neuron projection
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0042734  presynaptic membrane
GO:0008021  synaptic vesicle

Molecular Function

GO:0005262  calcium channel activity
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0004972  N-methyl-D-aspartate selective glutamate receptor activity
GO:0005515  protein binding
GO:0008270  zinc ion binding