glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Synonym

hNR2A, NMDAR2A, GRIN2A, N-methyl D-aspartate receptor subtype 2A, NR2A

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:46.20

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:59

adipose:-

bone:-

skin:-

GeneChip

nodata

CAGE

cerebrum:2.42

cerebellum:-

brain stem:0.56

corpus callosum/glia:1.49

pineal gland:0.47

peripheral nerve:-

spine:0.89

retina:-

eye:-

artery/aorta:0.95

vein:0.79

lymphnode:0.12

peripheral blood:-

spleen:0

thymus:0.18

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.14

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.01

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:35.60

breast:-

salivary:-

GeneChip

nodata

CAGE

uterus:0.43

placenta:0

prostate:0.33

ovary:0.52

testis:0.69

heart:0.24

muscle:0.25

esophagus:0.63

stomach:-

intestine:0.21

colon:0.15

liver/hepato:0

lung:0.10

bladder:0.58

kidney:0.27

pituitary:0.10

thyroid/parathyroid:0.12

adrenal gland:-

pancreas:0.58

breast:0

salivary:0.83

RNA-seq

uterus:-

placenta:-

prostate:0

ovary:0.01

testis:0.04

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0

adrenal gland:0.02

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_001134408
Gene ID	2903
Unigene ID	Hs.411472
Probe set ID	-
Ensembl ID	ENSG00000183454
GTEx ID	ENSG00000183454

Orthologous Gene

Mouse[1]	NM_008170
Rat [0]

Chromosomal Region

16p13.2 [9,847,261 - 10,276,611]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001320	Ionotropic glutamate receptor
IPR001508	NMDA receptor

Gene Ontology (GO ID)

Biological Process

GO:0033058	directional locomotion
GO:0042417	dopamine metabolic process
GO:0007215	glutamate signaling pathway
GO:0007611	learning or memory
GO:0007613	memory
GO:0042177	negative regulation of protein catabolic process
GO:0022008	neurogenesis
GO:0043065	positive regulation of apoptosis
GO:0008104	protein localization
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0051930	regulation of sensory perception of pain
GO:0048167	regulation of synaptic plasticity
GO:0001975	response to amphetamine
GO:0042493	response to drug
GO:0045471	response to ethanol
GO:0009611	response to wounding
GO:0019233	sensory perception of pain
GO:0042428	serotonin metabolic process
GO:0030431	sleep
GO:0001964	startle response
GO:0007268	synaptic transmission
GO:0006810	transport
GO:0008542	visual learning

Cellular Component

GO:0030054	cell junction
GO:0009986	cell surface
GO:0005887	integral to plasma membrane
GO:0017146	N-methyl-D-aspartate selective glutamate receptor complex
GO:0043005	neuron projection
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0042734	presynaptic membrane
GO:0008021	synaptic vesicle

Molecular Function

GO:0005262	calcium channel activity
GO:0005234	extracellular-glutamate-gated ion channel activity
GO:0004972	N-methyl-D-aspartate selective glutamate receptor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function