glycogen synthase kinase 3 alpha

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Synonym

Glycogen synthase kinase-3 alpha, GSK3A, glycogen synthase kinase 3 alpha, GSK-3 alpha, DKFZp686D0638

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:73.50 cerebellum:50.40 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:122.70 spine:112.30 retina:- eye:170.40 artery/aorta:- vein:66.60 lymphnode:121.30 peripheral blood:18.20 spleen:94.50 thymus:25.80 bone marrow:118.10 adipose:- bone:25.60 skin:62.40
GeneChip cerebrum:6.72 cerebellum:6.68 brain stem:6.71 corpus callosum/glia:6.50 pineal gland:- peripheral nerve:6.64 spine:6.60 retina:- eye:- artery/aorta:6.79 vein:6.64 lymphnode:6.49 peripheral blood:- spleen:6.36 thymus:6.34 bone marrow:6.75 adipose:6.64 bone:- skin:6.52
CAGE cerebrum:4.20 cerebellum:- brain stem:4.13 corpus callosum/glia:4.22 pineal gland:3.67 peripheral nerve:- spine:3.58 retina:- eye:- artery/aorta:3.58 vein:3.59 lymphnode:3.38 peripheral blood:- spleen:3.48 thymus:3.61 bone marrow:- adipose:3.26 bone:- skin:-
RNA-seq cerebrum:4.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.68 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.79 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:87.40 prostate:56.30 ovary:74.50 testis:51.90 heart:63.90 muscle:20.10 esophagus:- stomach:42.50 intestine:64.80 colon:288.30     liver/hepato:-        lung:63.50    bladder:125.60 kidney:187.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:83.60 salivary:328.40
GeneChip uterus:6.49 placenta:6.57 prostate:6.37 ovary:6.32 testis:6.62 heart:6.52 muscle:6.59 esophagus:6.64 stomach:6.54 intestine:6.82 colon:6.68 liver/hepato:6.57 lung:6.44 bladder:- kidney:6.53 pituitary:6.93 thyroid/parathyroid:6.53 adrenal gland:6.54 pancreas:7.35 breast:6.36 salivary:6.30
CAGE uterus:3.47 placenta:3.61 prostate:3.67 ovary:3.49 testis:3.95 heart:3.51 muscle:3.59 esophagus:3.58 stomach:- intestine:4.13 colon:3.72     liver/hepato:3.39    lung:3.46 bladder:3.45 kidney:3.67 pituitary:3.19 thyroid/parathyroid:3.71 adrenal gland:- pancreas:3.34 breast:3.60 salivary:3.42
RNA-seq uterus:- placenta:- prostate:4.87 ovary:3.93 testis:4.67 heart:3.82 muscle:5.35 esophagus:- stomach:- intestine:- colon:4.10     liver/hepato:3.52        lung:4.55    bladder:- kidney:4.14 pituitary:- thyroid/parathyroid:4.23 adrenal gland:3.68 pancreas:- breast:3.66 salivary:-

IDs

Refseq ID NM_019884
Gene ID 2931
Unigene ID Hs.466828
Probe set ID 632_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000105723
GTEx ID ENSG00000105723

Orthologous Gene

Mouse[1]  NM_001031667
Rat[1]  NM_017344

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0006987  activation of signaling protein activity involved in unfolded protein response
GO:0003214  cardiac left ventricle morphogenesis
GO:0016477  cell migration
GO:0044267  cellular protein metabolic process
GO:0032869  cellular response to insulin stimulus
GO:0071285  cellular response to lithium ion
GO:0071407  cellular response to organic cyclic substance
GO:0030968  endoplasmic reticulum unfolded protein response
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0006349  genetic imprinting
GO:0005977  glycogen metabolic process
GO:0044027  hypermethylation of CpG island
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0046325  negative regulation of glucose import
GO:0045719  negative regulation of glycogen biosynthetic process
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0032007  negative regulation of TOR signaling pathway
GO:0051348  negative regulation of transferase activity
GO:0010905  negative regulation of UDP-glucose catabolic process
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007399  nervous system development
GO:0048015  phosphoinositide-mediated signaling
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0045823  positive regulation of heart contraction
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0045732  positive regulation of protein catabolic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0003073  regulation of systemic arterial blood pressure
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0005515  protein binding
GO:0034236  protein kinase A catalytic subunit binding
GO:0004674  protein serine/threonine kinase activity
GO:0050321  tau-protein kinase activity