ubiquitin specific peptidase 25

 jump to detail

Synonym

Ubiquitin carboxyl-terminal hydrolase 25, Ubiquitin thioesterase 25, USP25, Ubiquitin-specific-processing protease 25, USP21, USP on chromosome 21, ubiquitin specific peptidase 25, Deubiquitinating enzyme 25, ubiquitin specific protease 25

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:32 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:- retina:118.60 eye:23.50 artery/aorta:- vein:133.30 lymphnode:60.70 peripheral blood:18.20 spleen:18.90 thymus:51.50 bone marrow:118.10 adipose:40.30 bone:25.60 skin:57.60
GeneChip cerebrum:6.41 cerebellum:5.53 brain stem:6.31 corpus callosum/glia:6 pineal gland:- peripheral nerve:7.16 spine:6.15 retina:- eye:- artery/aorta:6.82 vein:6.75 lymphnode:6.75 peripheral blood:- spleen:6.66 thymus:7.13 bone marrow:6.39 adipose:7.22 bone:- skin:6.70
CAGE cerebrum:2.71 cerebellum:- brain stem:2.62 corpus callosum/glia:2.67 pineal gland:2.89 peripheral nerve:- spine:2.87 retina:- eye:- artery/aorta:3.11 vein:3.13 lymphnode:3.09 peripheral blood:- spleen:3.13 thymus:3.26 bone marrow:- adipose:3.42 bone:- skin:-
RNA-seq cerebrum:3.37 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.45 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.80 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:105.60 prostate:67.60 ovary:- testis:90.90 heart:38.30 muscle:60.30 esophagus:- stomach:21.20 intestine:64.80 colon:8.50     liver/hepato:63.30        lung:29.30    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:80 breast:167.30 salivary:-
GeneChip uterus:7.44 placenta:7.01 prostate:6.93 ovary:6.84 testis:8.08 heart:6.97 muscle:8.49 esophagus:6.90 stomach:6.35 intestine:6.46 colon:5.69 liver/hepato:6.44 lung:7.16 bladder:- kidney:6.32 pituitary:6.07 thyroid/parathyroid:6.39 adrenal gland:6.43 pancreas:5.89 breast:6.58 salivary:6.24
CAGE uterus:3.67 placenta:3.47 prostate:3.30 ovary:3.36 testis:2.81 heart:3.44 muscle:3.95 esophagus:3.23 stomach:- intestine:3.18 colon:3.44     liver/hepato:2.77    lung:3.86 bladder:3.30 kidney:3.21 pituitary:2.75 thyroid/parathyroid:3.00 adrenal gland:- pancreas:2.54 breast:4.04 salivary:2.50
RNA-seq uterus:- placenta:- prostate:3.88 ovary:3.65 testis:4.37 heart:3.68 muscle:5.12 esophagus:- stomach:- intestine:- colon:3.48     liver/hepato:2.53        lung:3.40    bladder:- kidney:3.73 pituitary:- thyroid/parathyroid:3.86 adrenal gland:3.40 pancreas:- breast:3.85 salivary:-

Gene Information

IDs

Refseq ID NM_013396
Gene ID 29761
Unigene ID Hs.473370
Probe set ID 220419_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000155313
GTEx ID ENSG00000155313

Orthologous Gene

Mouse[1]  NM_013918
Rat[1]  NM_001107114

Chromosomal Region

21q21.1  [17,102,344  -  17,252,377]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10612803
10644437
10830953
11597335
12477932
12838346
14702039
15231748
16501887
18523997
18538659
19013454
19165232
19440361
19615732
19760754
19909739
20379614
20972266
21139048
21145461
21480003
21738487
21890473
21906983
21963094
22053931
22118674
22195557
22590560
22863883
22939629
23000965
23314748
24260525

Gene Ontology  (GO ID)

Biological Process

GO:0071108  protein K48-linked deubiquitination
GO:0070536  protein K63-linked deubiquitination
GO:0006464  protein modification process
GO:0006508  proteolysis
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0008233  peptidase activity
GO:0005515  protein binding
GO:0032183  SUMO binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity