guanylate cyclase activator 2B (uroguanylin)

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Synonym

GCAP-II, guanylate cyclase activator 2B (uroguanylin), UGN, Guanylate cyclase activator 2B precursor, GUCA2B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.30 cerebellum:4.33 brain stem:4.33 corpus callosum/glia:4.15 pineal gland:- peripheral nerve:4.09 spine:4.17 retina:- eye:- artery/aorta:4.35 vein:4.51 lymphnode:4.27 peripheral blood:- spleen:4.10 thymus:4.03 bone marrow:4.32 adipose:4.31 bone:- skin:4.48
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0.09 thymus:0.12 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.13 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:17     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.18 placenta:4.13 prostate:4.19 ovary:4.13 testis:4.24 heart:4.34 muscle:4.59 esophagus:4.45 stomach:4.32 intestine:4.44 colon:5.08 liver/hepato:4.49 lung:4.21 bladder:- kidney:4.31 pituitary:4.44 thyroid/parathyroid:4.13 adrenal gland:4.37 pancreas:4.56 breast:4.10 salivary:4.43
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:5.12 colon:3.88     liver/hepato:1.41    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0.58 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0.05 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:1.63     liver/hepato:0.53        lung:0    bladder:- kidney:0.03 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_007102
Gene ID 2981
Unigene ID Hs.32966
Probe set ID 207502_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000044012
GTEx ID ENSG00000044012

Orthologous Gene

Mouse[1]  NM_008191
Rat [0]  

Chromosomal Region

1p34.2  [42,619,092  -  42,621,495]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7589507
8141334
8519795
8605041
9268639
9328941
9622502
9698373
9774236
11380922
11431160
11889121
12477932
12548407
15489334
15780094
17582287
18037771

Gene Ontology  (GO ID)

Biological Process

GO:0007589  body fluid secretion
GO:0006182  cGMP biosynthetic process
GO:0007588  excretion
GO:0045776  negative regulation of blood pressure

Cellular Component

GO:0005576  extracellular region

Molecular Function

GO:0008048  calcium sensitive guanylate cyclase activator activity