guanylate kinase 1

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Synonym

Guanylate kinase, GMP kinase, GMK, guanylate kinase 1, GUK1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:110.20 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:741.70 peripheral nerve:61.30 spine:112.30 retina:237.30 eye:182.20 artery/aorta:60 vein:- lymphnode:182 peripheral blood:36.40 spleen:94.50 thymus:12.90 bone marrow:59 adipose:40.30 bone:89.60 skin:76.80
GeneChip cerebrum:8.72 cerebellum:7.99 brain stem:8.54 corpus callosum/glia:8.44 pineal gland:- peripheral nerve:8.48 spine:8.50 retina:- eye:- artery/aorta:8.57 vein:8.30 lymphnode:8 peripheral blood:- spleen:8.08 thymus:8.55 bone marrow:8.78 adipose:8.44 bone:- skin:8.81
CAGE cerebrum:5.19 cerebellum:- brain stem:4.84 corpus callosum/glia:4.65 pineal gland:5.34 peripheral nerve:- spine:4.85 retina:- eye:- artery/aorta:5.25 vein:4.62 lymphnode:4.50 peripheral blood:- spleen:4.30 thymus:4.36 bone marrow:- adipose:4.27 bone:- skin:-
RNA-seq cerebrum:1.16 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.89 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:218.70 placenta:72.90 prostate:123.90 ovary:74.50 testis:64.90 heart:319.30 muscle:100.50 esophagus:- stomach:42.50 intestine:- colon:144.20     liver/hepato:52.80        lung:161.30    bladder:- kidney:62.40 pituitary:116 thyroid/parathyroid:- adrenal gland:152.40 pancreas:160 breast:83.60 salivary:-
GeneChip uterus:8.07 placenta:7.59 prostate:8.01 ovary:8.01 testis:8.14 heart:7.97 muscle:7.32 esophagus:9.04 stomach:8.05 intestine:8.02 colon:7.88 liver/hepato:8 lung:8.55 bladder:- kidney:8.13 pituitary:7.81 thyroid/parathyroid:7.89 adrenal gland:8.38 pancreas:8 breast:8.41 salivary:8.27
CAGE uterus:4.21 placenta:4.24 prostate:4.45 ovary:4.32 testis:4.37 heart:4.95 muscle:4.21 esophagus:4.84 stomach:- intestine:4.36 colon:4.67     liver/hepato:4.78    lung:4.70 bladder:4.55 kidney:4.54 pituitary:4.19 thyroid/parathyroid:4.23 adrenal gland:- pancreas:4.99 breast:5.00 salivary:4.40
RNA-seq uterus:- placenta:- prostate:4.30 ovary:5.31 testis:5.11 heart:3.56 muscle:2.87 esophagus:- stomach:- intestine:- colon:1.84     liver/hepato:4.60        lung:5.53    bladder:- kidney:4.66 pituitary:- thyroid/parathyroid:2.35 adrenal gland:2.79 pancreas:- breast:1.12 salivary:-

Gene Information

IDs

Refseq ID NM_001159391
Gene ID 2987
Unigene ID Hs.376933
Probe set ID 200075_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000143774
GTEx ID ENSG00000143774

Orthologous Gene

Mouse[2]  NM_001159410, NM_008193
Rat [0]  

Chromosomal Region

1q42.13  [228,327,663  -  228,336,685]

Gene Family (Interpro ID)

IPR008144  Guanylate kinase
IPR017665  Guanylate kinase, sub-group
IPR008145  Guanylate kinase/L-type calcium channel

Link to Pubmed  (Pubmed ID)

211390
2164269
6249178
6260205
8647247
8663313
12107411
12477932
15231747
15489334
16341674
16832584
21139048
21565611
21890473
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0017144  drug metabolic process
GO:0015949  nucleobase, nucleoside and nucleotide interconversion
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0006163  purine nucleotide metabolic process

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0004385  guanylate kinase activity