CCR4-NOT transcription complex, subunit 7

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Synonym

BTG1-binding factor 1, CCR4-associated factor 1, CCR4-NOT transcription complex, subunit 7, hCAF-1, CCR4-NOT transcription complex subunit 7, CNOT7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.31 cerebellum:8.41 brain stem:8.05 corpus callosum/glia:8.14 pineal gland:- peripheral nerve:8.08 spine:8.11 retina:- eye:- artery/aorta:7.82 vein:7.96 lymphnode:8.67 peripheral blood:- spleen:8.91 thymus:9.15 bone marrow:7.87 adipose:8.14 bone:- skin:8.03
CAGE cerebrum:3.60 cerebellum:- brain stem:3.32 corpus callosum/glia:3.07 pineal gland:3.70 peripheral nerve:- spine:3.32 retina:- eye:- artery/aorta:2.97 vein:3.66 lymphnode:3.42 peripheral blood:- spleen:3.57 thymus:4.18 bone marrow:- adipose:3.23 bone:- skin:-
RNA-seq cerebrum:4.35 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.46 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.90 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.55 placenta:8.38 prostate:8.56 ovary:9 testis:8.95 heart:8.28 muscle:8.78 esophagus:8.35 stomach:8.40 intestine:8.32 colon:8.08 liver/hepato:8.34 lung:8.34 bladder:- kidney:8.46 pituitary:8.51 thyroid/parathyroid:9.14 adrenal gland:8.41 pancreas:8.04 breast:8.69 salivary:8.62
CAGE uterus:2.93 placenta:3.37 prostate:3.26 ovary:3.34 testis:3.61 heart:3.23 muscle:3.03 esophagus:3.22 stomach:- intestine:3.42 colon:3.04     liver/hepato:3.70    lung:3.25 bladder:3.19 kidney:3.25 pituitary:3.79 thyroid/parathyroid:3.54 adrenal gland:- pancreas:3.57 breast:3.33 salivary:2.78
RNA-seq uterus:- placenta:- prostate:4.65 ovary:4.89 testis:4.83 heart:3.97 muscle:4.67 esophagus:- stomach:- intestine:- colon:4.37     liver/hepato:3.66        lung:4.11    bladder:- kidney:4.67 pituitary:- thyroid/parathyroid:4.83 adrenal gland:4.37 pancreas:- breast:4.51 salivary:-

Gene Information

IDs

Refseq ID NM_013354
Gene ID 29883
Unigene ID -
Probe set ID 218250_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198791
GTEx ID ENSG00000198791

Orthologous Gene

Mouse[3]  NM_011135
Rat[1]  NM_001107313

Chromosomal Region

8p22  [17,086,737  -  17,104,387]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1538749
7791755
8125298
8889549
9712883
9820826
10602502
10637334
11136725
11429045
12477932
12845644
14702039
15489334
15769875
16344560
17264152
18056425
18084094
18377426
19276069
19322201
19558367
19605561
19716330
19946888
20098747
20211142
20360068
21139048
21832049
21900206
21906983
21963094
23236473
23275444
23824909
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0033962  cytoplasmic mRNA processing body assembly
GO:0000290  deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0043928  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0010467  gene expression
GO:0035195  gene silencing by miRNA
GO:0031047  gene silencing by RNA
GO:0016071  mRNA metabolic process
GO:0008285  negative regulation of cell proliferation
GO:0000288  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289  nuclear-transcribed mRNA poly(A) tail shortening
GO:0008284  positive regulation of cell proliferation
GO:0060213  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006417  regulation of translation
GO:0016070  RNA metabolic process
GO:0007165  signal transduction
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0030014  CCR4-NOT complex
GO:0000932  cytoplasmic mRNA processing body
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0000175  3'-5'-exoribonuclease activity
GO:0004532  exoribonuclease activity
GO:0046872  metal ion binding
GO:0004535  poly(A)-specific ribonuclease activity
GO:0005515  protein binding
GO:0003723  RNA binding
GO:0004871  signal transducer activity
GO:0003700  transcription factor activity