hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit

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Synonym

LCHAD, MGC1728, HADHA, HADH, 78 kDa gastrin-binding protein, TP-ALPHA, TP-alpha, MTPA

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:151.70

cerebellum:50.40

brain stem:-

corpus callosum/glia:175

pineal gland:-

peripheral nerve:61.30

spine:224.60

retina:118.60

eye:205.70

artery/aorta:119.90

vein:199.90

lymphnode:101.10

peripheral blood:236.80

spleen:56.70

thymus:309.20

bone marrow:314.90

adipose:161.30

bone:166.30

skin:235.20

GeneChip

cerebrum:6.58

cerebellum:6.40

brain stem:7.01

corpus callosum/glia:6.85

pineal gland:-

peripheral nerve:6.98

spine:7.09

retina:-

eye:-

artery/aorta:7.59

vein:7.16

lymphnode:7.01

peripheral blood:-

spleen:6.78

thymus:7.28

bone marrow:7.06

adipose:7.52

bone:-

skin:7.69

CAGE

cerebrum:4.58

cerebellum:-

brain stem:5.01

corpus callosum/glia:5.16

pineal gland:4.15

peripheral nerve:-

spine:5.23

retina:-

eye:-

artery/aorta:4.72

vein:4.87

lymphnode:4.97

peripheral blood:-

spleen:5.02

thymus:4.91

bone marrow:-

adipose:5.59

bone:-

skin:-

RNA-seq

cerebrum:5.12

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.42

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:6.72

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:200.50

placenta:244.10

prostate:157.70

ovary:223.60

testis:225

heart:459.80

muscle:502.30

esophagus:-

stomach:63.70

intestine:324

colon:415.50

liver/hepato:147.80

lung:161.30

bladder:502.40

kidney:228.70

pituitary:347.90

thyroid/parathyroid:-

adrenal gland:304.70

pancreas:115.60

breast:260.20

salivary:-

GeneChip

uterus:7.17

placenta:6.59

prostate:7.39

ovary:7.33

testis:7.35

heart:7.81

muscle:8.33

esophagus:7.49

stomach:6.77

intestine:7.54

colon:7.30

liver/hepato:7.71

lung:7.09

bladder:-

kidney:7.52

pituitary:7.05

thyroid/parathyroid:6.93

adrenal gland:7.42

pancreas:7.38

breast:7.41

salivary:7.14

CAGE

uterus:5.00

placenta:4.84

prostate:5.02

ovary:5.17

testis:5.01

heart:5.63

muscle:6.05

esophagus:5.29

stomach:-

intestine:5.99

colon:5.32

liver/hepato:5.93

lung:4.71

bladder:5.17

kidney:5.51

pituitary:4.92

thyroid/parathyroid:5.02

adrenal gland:-

pancreas:5.37

breast:4.79

salivary:5.14

RNA-seq

uterus:-

placenta:-

prostate:6.10

ovary:6.16

testis:5.92

heart:7.19

muscle:7.19

esophagus:-

stomach:-

intestine:-

colon:6.09

liver/hepato:5.95

lung:5.49

bladder:-

kidney:5.99

pituitary:-

thyroid/parathyroid:6.28

adrenal gland:5.85

pancreas:-

breast:6.35

salivary:-

IDs

Refseq ID	NM_000182
Gene ID	3030
Unigene ID	Hs.516032
Probe set ID	208630_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000084754
GTEx ID	ENSG00000084754

Orthologous Gene

Mouse[1]	NM_178878
Rat[2]	NM_130826

Chromosomal Region

2p23.3 [26,413,504 - 26,467,594]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0044255	cellular lipid metabolic process
GO:0006635	fatty acid beta-oxidation
GO:0046474	glycerophospholipid biosynthetic process
GO:0006644	phospholipid metabolic process
GO:0042493	response to drug
GO:0032868	response to insulin stimulus

Cellular Component

GO:0005737	cytoplasm
GO:0016507	fatty acid beta-oxidation multienzyme complex
GO:0005743	mitochondrial inner membrane
GO:0042645	mitochondrial nucleoid
GO:0005739	mitochondrion
GO:0005730	nucleolus

Molecular Function

GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
GO:0003985	acetyl-CoA C-acetyltransferase activity
GO:0000062	acyl-CoA binding
GO:0004300	enoyl-CoA hydratase activity
GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0016508	long-chain-enoyl-CoA hydratase activity
GO:0051287	NAD or NADH binding
GO:0005515	protein binding
GO:0032403	protein complex binding

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function