hemopoietic cell kinase

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Synonym

Hemopoietic cell kinase, hemopoietic cell kinase, Tyrosine-protein kinase HCK, p59-HCK/p60-HCK, HCK, JTK9

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:4.81

cerebellum:4.57

brain stem:4.99

corpus callosum/glia:5.51

pineal gland:-

peripheral nerve:5.30

spine:5.48

retina:-

eye:-

artery/aorta:5.05

vein:5.03

lymphnode:6.78

peripheral blood:-

spleen:7.35

thymus:5.38

bone marrow:8.79

adipose:5.47

bone:-

skin:5.95

CAGE

cerebrum:2.47

cerebellum:-

brain stem:3.01

corpus callosum/glia:2.97

pineal gland:1.97

peripheral nerve:-

spine:3.37

retina:-

eye:-

artery/aorta:2.58

vein:3.49

lymphnode:4.18

peripheral blood:-

spleen:5.09

thymus:2.71

bone marrow:-

adipose:3.61

bone:-

skin:-

RNA-seq

nodata

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:4.76

placenta:5.56

prostate:4.57

ovary:4.93

testis:4.45

heart:5.02

muscle:4.53

esophagus:4.94

stomach:4.96

intestine:5.83

colon:5.40

liver/hepato:5.03

lung:7.51

bladder:-

kidney:4.30

pituitary:4.36

thyroid/parathyroid:4.48

adrenal gland:4.66

pancreas:5.12

breast:5.26

salivary:4.47

CAGE

uterus:2.07

placenta:3.18

prostate:2.59

ovary:2.44

testis:1.79

heart:2.80

muscle:1.91

esophagus:2.23

stomach:-

intestine:2.97

colon:2.84

liver/hepato:2.97

lung:3.91

bladder:2.37

kidney:2.29

pituitary:2.12

thyroid/parathyroid:2.38

adrenal gland:-

pancreas:1.87

breast:2.34

salivary:1.82

RNA-seq

nodata

IDs

Refseq ID	NM_002110
Gene ID	3055
Unigene ID	-
Probe set ID	208018_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000101336
GTEx ID	ENSG00000101336

Orthologous Gene

Mouse[1]	NM_001172117, NM_010407
Rat [0]

Chromosomal Region

20q11.21 [30,639,991 - 30,689,659]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0007155	cell adhesion
GO:0019221	cytokine-mediated signaling pathway
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0002758	innate immune response-activating signal transduction
GO:0007229	integrin-mediated signaling pathway
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0043299	leukocyte degranulation
GO:0002522	leukocyte migration during immune response
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0007498	mesoderm development
GO:0043066	negative regulation of apoptosis
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0030838	positive regulation of actin filament polymerization
GO:0008284	positive regulation of cell proliferation
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0008360	regulation of cell shape
GO:0050690	regulation of defense response to virus by virus
GO:0050727	regulation of inflammatory response
GO:0050764	regulation of phagocytosis
GO:0051090	regulation of transcription factor activity
GO:0045728	respiratory burst after phagocytosis
GO:0016032	viral reproduction
GO:0019048	virus-host interaction

Cellular Component

GO:0005884	actin filament
GO:0005901	caveola
GO:0042995	cell projection
GO:0005829	cytosol
GO:0031234	extrinsic to internal side of plasma membrane
GO:0005925	focal adhesion
GO:0005794	Golgi apparatus
GO:0005764	lysosome
GO:0005634	nucleus
GO:0030133	transport vesicle

Molecular Function

GO:0005524	ATP binding
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0005515	protein binding
GO:0004713	protein tyrosine kinase activity

hemopoietic cell kinase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function