neuregulin 1

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Synonym

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Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:56.90 cerebellum:12.60 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:112.30 retina:118.60 eye:47 artery/aorta:- vein:133.30 lymphnode:- peripheral blood:36.40 spleen:- thymus:- bone marrow:- adipose:- bone:25.60 skin:38.40
GeneChip cerebrum:5.20 cerebellum:4.98 brain stem:5.46 corpus callosum/glia:4.93 pineal gland:- peripheral nerve:5.32 spine:4.85 retina:- eye:- artery/aorta:5.08 vein:5.32 lymphnode:4.83 peripheral blood:- spleen:4.72 thymus:4.61 bone marrow:5.14 adipose:5.08 bone:- skin:5.08
CAGE cerebrum:2.05 cerebellum:- brain stem:2.18 corpus callosum/glia:0.76 pineal gland:4.69 peripheral nerve:- spine:1.80 retina:- eye:- artery/aorta:1.57 vein:0.59 lymphnode:1.33 peripheral blood:- spleen:1.39 thymus:0.61 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.05 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:11.30 ovary:- testis:30.30 heart:25.50 muscle:- esophagus:- stomach:21.20 intestine:64.80 colon:17     liver/hepato:21.10        lung:14.70    bladder:- kidney:166.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:65.10 salivary:-
GeneChip uterus:4.78 placenta:5.01 prostate:4.74 ovary:4.77 testis:5.08 heart:4.93 muscle:5.33 esophagus:4.88 stomach:5.24 intestine:5.05 colon:5.13 liver/hepato:5.33 lung:4.91 bladder:- kidney:5.13 pituitary:5.14 thyroid/parathyroid:4.76 adrenal gland:5.15 pancreas:5.68 breast:4.77 salivary:5.03
CAGE uterus:2.17 placenta:0.24 prostate:1.88 ovary:0.95 testis:1.20 heart:1.30 muscle:0.34 esophagus:0.94 stomach:- intestine:2.12 colon:2.19     liver/hepato:2.64    lung:2.29 bladder:1.83 kidney:2.60 pituitary:2.83 thyroid/parathyroid:2.24 adrenal gland:- pancreas:0 breast:0 salivary:1.15
RNA-seq uterus:- placenta:- prostate:0.65 ovary:0.18 testis:0.70 heart:0.06 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0        lung:0.00    bladder:- kidney:0.02 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.04 pancreas:- breast:0.15 salivary:-

IDs

Refseq ID NM_001159996
Gene ID 3084
Unigene ID Hs.453951
Probe set ID 208230_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000157168
GTEx ID ENSG00000157168

Orthologous Gene

Mouse[1]  NM_178591
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1348215
1350381
7509448
7514177
7556068
7592681
7689552
7721889
7730382
7782315
7876250
7903175
8062828
8095334
8096067
8125298
8325659
8702572
9168114
9168115
9333014
9342050
9553078
9565587
9685409
10372964
10523851
10537356
10559227
10585499
10597312
11116142
11389077
11555649
11896060
12082616
12145742
12204892
12471041
12477932
12478479
12509456
12528817
12556556
12600989
12646923
12768307
12800145
12808428
12874607
14569272
14632199
14647391
14699424
14702039
14729827
14966480
15007393
15073182
15155732
15159416
15162166
15197397
15219675
15248869
15276238
15303101
15326116
15466169
15489334
15494726
15498868
15527969
15538186
15545978
15584912
15609326
15645137
15703820
15897877
15939841
16082692
16155362
16158055
16189508
16219117
16219118
16249994
16287046
16326006
16344560
16412517
16428439
16442083
16446404
16470843
16483744
16520822
16526041
16618933
16638076
16687441
16690615
16730337
16767099
16825199
16867224
16868568
16891421
16940976
17033632
17072305
17214955
17275115
17300918
17336907
17336946
17366345
17405926
17408693
17432114
17447867
17499242
17503451
17519028
17562386
17565985
17598910
17602072
17631867
17652086
17884806
17901998
17903296
17925794
17941827
17962208
18032396
18159252
18180429
18193072
18198266
18234478
18255317
18282690
18286587
18291420
18395550
18455303
18455369
18466879
18466881
18470533
18494263
18494554
18497096
18516516
18543275
18571900
18583979
18584117
18585932
18606232
18668031
18704261
18714568
18728681
18798975
18799465
18806920
19054571
19058791
19086053
19127563
19148499
19150438
19156152
19184335
19196962
19199244
19229203
19269083
19306381
19328558
19339916
19350564
19367581
19367584
19394386
19439994
19448847
19449332
19497323
19521112
19545856
19556605
19569180
19573260
19575259
19594860
19597049
19626024
19644050
19652122
19659570
19733651
19736351
19782967
19797898
19801490
19802002
19913121
19913623
19937977
19965935
19967439
20036336
20061032
20102668
20182055
20215529
20218976
20227043
20371257
20374152
20379614
20427670
20435087
20472376
20497232
20520724
20526724
20580130
20582876
20625696
20628086
20638435
20671236
20682778
20736300
20800603
20921115
20926259
20927045
20978455
21035784
21041608
21057508
21127983
21234898
21239627
21246584
21247898
21283760
21368034
21371516
21437657
21467033
21512575
21546767
21555713
21576249
21653853
21706185
21716252
21745728
21792199
21840482
21858616
21865659
21965611
22019858
22027878
22042562
22052506
22158511
22183611
22200588
22209534
22216327
22226049
22226548
22249266
22249457
22267200
22350758
22377709
22378022
22378872
22414959
22424243
22425775
22467496
22494484
22504067
22520967
22563075
22574178
22590542
22613991
22739235
22790889
22832904
22886427
22891299
22944276
22968213
22974608
22999558
23032943
23035098
23104879
23148218
23213231
23247143
23253390
23301017
23308187
23328545
23360725
23399902
23400839
23408906
23468880
23480537
23489597
23524320
23572145
23590603
23625463
23632455
23739962
23870195
23934736
23937725
24083437
24097984
24112719
24152577
24309211
24324551

Gene Ontology  (GO ID)

Biological Process

GO:0007171  activation of transmembrane receptor protein tyrosine kinase activity
GO:0003161  cardiac conduction system development
GO:0055007  cardiac muscle cell differentiation
GO:0060379  cardiac muscle cell myoblast differentiation
GO:0007154  cell communication
GO:0016477  cell migration
GO:0000902  cell morphogenesis
GO:0008283  cell proliferation
GO:0043624  cellular protein complex disassembly
GO:0009790  embryonic development
GO:0060956  endocardial cell differentiation
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0021781  glial cell fate commitment
GO:0045087  innate immune response
GO:0007626  locomotory behavior
GO:0030879  mammary gland development
GO:0000165  MAPKKK cascade
GO:0010667  negative regulation of cardiac muscle cell apoptosis
GO:0042177  negative regulation of protein catabolic process
GO:0051048  negative regulation of secretion
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007399  nervous system development
GO:0014032  neural crest cell development
GO:0048663  neuron fate commitment
GO:0045213  neurotransmitter receptor metabolic process
GO:0007422  peripheral nervous system development
GO:0048015  phosphoinositide-mediated signaling
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0045785  positive regulation of cell adhesion
GO:0030307  positive regulation of cell growth
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0046579  positive regulation of Ras protein signal transduction
GO:0051155  positive regulation of striated muscle cell differentiation
GO:0043497  regulation of protein heterodimerization activity
GO:0043496  regulation of protein homodimerization activity
GO:0007416  synapse assembly
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0055012  ventricular cardiac muscle cell differentiation
GO:0003222  ventricular trabecular myocardium morphogenesis
GO:0042060  wound healing

Cellular Component

GO:0016324  apical plasma membrane
GO:0030424  axon
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0031594  neuromuscular junction
GO:0005634  nucleus

Molecular Function

GO:0005125  cytokine activity
GO:0005176  ErbB-2 class receptor binding
GO:0043125  ErbB-3 class receptor binding
GO:0008083  growth factor activity
GO:0005515  protein binding
GO:0030296  protein tyrosine kinase activator activity
GO:0005102  receptor binding
GO:0030971  receptor tyrosine kinase binding
GO:0003712  transcription cofactor activity
GO:0030297  transmembrane receptor protein tyrosine kinase activator activity