high mobility group AT-hook 1

Synonym

MGC12816, High mobility group protein-R, high mobility group AT-hook 1, High mobility group protein HMG-I/HMG-Y, HMG-I(Y), MGC4854, HMGA1, HMG-R, High mobility group AT-hook protein 1, MGC4242, HMGIY, High mobility group protein A1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:75.80

cerebellum:314.80

brain stem:-

corpus callosum/glia:408.30

pineal gland:-

peripheral nerve:30.70

spine:112.30

retina:-

eye:458.40

artery/aorta:419.70

vein:599.80

lymphnode:151.70

peripheral blood:437.20

spleen:189.10

thymus:1185.30

bone marrow:39.40

adipose:161.30

bone:243.10

skin:172.80

GeneChip

cerebrum:6.66

cerebellum:6.53

brain stem:6.61

corpus callosum/glia:6.14

pineal gland:-

peripheral nerve:6.52

spine:6.35

retina:-

eye:-

artery/aorta:6.56

vein:6.39

lymphnode:8.17

peripheral blood:-

spleen:7.13

thymus:8.38

bone marrow:8.32

adipose:6.74

bone:-

skin:7.83

CAGE

cerebrum:0.56

cerebellum:-

brain stem:0.60

corpus callosum/glia:0.52

pineal gland:0.83

peripheral nerve:-

spine:0.82

retina:-

eye:-

artery/aorta:0.47

vein:0.96

lymphnode:0.80

peripheral blood:-

spleen:0.25

thymus:1.61

bone marrow:-

adipose:0.46

bone:-

skin:-

RNA-seq

cerebrum:0

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.69

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.56

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:163.90

prostate:101.40

ovary:111.80

testis:220.60

heart:166

muscle:200.90

esophagus:342.80

stomach:106.20

intestine:777.60

colon:135.70

liver/hepato:137.20

lung:122.20

bladder:502.40

kidney:72.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:44.50

breast:83.60

salivary:-

GeneChip

uterus:6.15

placenta:7.37

prostate:6.14

ovary:6

testis:8.86

heart:6.37

muscle:6.92

esophagus:9.04

stomach:7.30

intestine:7.37

colon:7.78

liver/hepato:6.04

lung:6.67

bladder:-

kidney:6.26

pituitary:6.11

thyroid/parathyroid:6.91

adrenal gland:5.71

pancreas:6.34

breast:7.52

salivary:7.33

CAGE

uterus:0.49

placenta:1.30

prostate:0.44

ovary:0.07

testis:1.70

heart:0.68

muscle:0.86

esophagus:0.94

stomach:-

intestine:1.22

colon:0.97

liver/hepato:0

lung:0.42

bladder:0.58

kidney:0.27

pituitary:0.34

thyroid/parathyroid:0.37

adrenal gland:-

pancreas:1.21

breast:0

salivary:0.83

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.08

testis:0.55

heart:0.00

muscle:1.37

esophagus:-

stomach:-

intestine:-

colon:0.44

liver/hepato:0.00

lung:0.26

bladder:-

kidney:0.01

pituitary:-

thyroid/parathyroid:0.29

adrenal gland:0.26

pancreas:-

breast:0.33

salivary:-

IDs

Refseq ID	NM_002131
Gene ID	3159
Unigene ID	Hs.518805
Probe set ID	206074_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000137309
GTEx ID	ENSG00000137309

Orthologous Gene

Mouse[29]	NM_001025427, NM_001039356, NM_001166535, NM_001166536, NM_001166537, NM_001166539, NM_001166540, NM_001166541, NM_001166542, NM_001166543, NM_001166544, NM_001166545, NM_001166546, NM_016660, NM_001166476
Rat[1]	NM_139327, NM_001039356, NM_001166535, NM_001166536, NM_001166537, NM_001166539, NM_001166540, NM_001166541, NM_001166542, NM_001166543, NM_001166544, NM_001166545, NM_001166546, NM_016660, NM_001166476

Chromosomal Region

6p21.31 [34,204,577 - 34,214,008]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR020478	A.T hook-like
IPR017956	AT hook, DNA-binding motif
IPR000116	High mobility group, HMG-I/HMG-Y

Gene Ontology (GO ID)

Biological Process

GO:0006284	base-excision repair
GO:0006268	DNA unwinding during replication
GO:0008285	negative regulation of cell proliferation
GO:0031936	negative regulation of chromatin silencing
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0006337	nucleosome disassembly
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006461	protein complex assembly
GO:0006355	regulation of transcription, DNA-dependent
GO:0009615	response to virus
GO:0006351	transcription, DNA-dependent
GO:0016032	viral reproduction
GO:0019048	virus-host interaction

Cellular Component

GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0051575	5'-deoxyribose-5-phosphate lyase activity
GO:0003680	AT DNA binding
GO:0003677	DNA binding
GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
GO:0019899	enzyme binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0042975	peroxisome proliferator activated receptor binding
GO:0005515	protein binding
GO:0042974	retinoic acid receptor binding
GO:0046965	retinoid X receptor binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

high mobility group AT-hook 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function