histamine N-methyltransferase

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Synonym

HNMT-S2, Histamine N-methyltransferase, HNMT-S1, HMT, histamine N-methyltransferase, HNMT

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:37.80 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:- vein:66.60 lymphnode:40.40 peripheral blood:36.40 spleen:- thymus:- bone marrow:19.70 adipose:- bone:12.80 skin:38.40
GeneChip cerebrum:6.25 cerebellum:5.81 brain stem:6.85 corpus callosum/glia:7.26 pineal gland:- peripheral nerve:6.68 spine:7.98 retina:- eye:- artery/aorta:7.67 vein:7.29 lymphnode:7.05 peripheral blood:- spleen:7.21 thymus:6 bone marrow:6.63 adipose:8.41 bone:- skin:7.24
CAGE cerebrum:2.73 cerebellum:- brain stem:2.98 corpus callosum/glia:2.78 pineal gland:2.13 peripheral nerve:- spine:3.40 retina:- eye:- artery/aorta:3.21 vein:2.87 lymphnode:2.94 peripheral blood:- spleen:3.48 thymus:0.99 bone marrow:- adipose:4.31 bone:- skin:-
RNA-seq cerebrum:2.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.71 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.67 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:51 prostate:22.50 ovary:37.30 testis:8.70 heart:25.50 muscle:20.10 esophagus:342.80 stomach:21.20 intestine:129.60 colon:33.90     liver/hepato:31.70        lung:48.90    bladder:- kidney:228.70 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:37.20 salivary:-
GeneChip uterus:8.72 placenta:7.29 prostate:8.68 ovary:8.66 testis:5.68 heart:6.80 muscle:5.19 esophagus:6.39 stomach:7.38 intestine:7.67 colon:7.31 liver/hepato:9.69 lung:7.99 bladder:- kidney:8.85 pituitary:5.57 thyroid/parathyroid:6.44 adrenal gland:6.41 pancreas:7.42 breast:7.96 salivary:6.62
CAGE uterus:3.73 placenta:3.13 prostate:3.72 ovary:3.97 testis:2.48 heart:2.84 muscle:1.68 esophagus:3.05 stomach:- intestine:2.99 colon:3.25     liver/hepato:4.11    lung:3.80 bladder:3.24 kidney:3.96 pituitary:2.17 thyroid/parathyroid:2.53 adrenal gland:- pancreas:2.41 breast:3.90 salivary:2.01
RNA-seq uterus:- placenta:- prostate:4.21 ovary:4.35 testis:3.75 heart:2.06 muscle:1.23 esophagus:- stomach:- intestine:- colon:3.84     liver/hepato:4.19        lung:3.30    bladder:- kidney:3.97 pituitary:- thyroid/parathyroid:2.64 adrenal gland:3.23 pancreas:- breast:5.00 salivary:-

Gene Information

IDs

Refseq ID NM_006895
Gene ID 3176
Unigene ID Hs.42151
Probe set ID 204112_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000150540
GTEx ID ENSG00000150540

Orthologous Gene

Mouse[1]  NM_080462
Rat [0]  

Chromosomal Region

2q22.1  [138,721,590  -  138,773,930]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7943261
8145732
8605025
9547362
10803682
11566133
12167489
12358773
12417108
12477932
12755416
12835614
12867290
14667820
15489334
15551002
15693910
15770103
15815621
15953854
16205835
16489678
16554448
16669609
16950574
17651147
17703412
17985251
18029348
18086566
18154359
18254975
18266724
18543121
19025430
19056867
19156168
19178400
19247692
19258923
19343046
19538200
19773194
19898482
20237496
20379614
20503287
20551163
20602615
21040557
21044950
21138759
21794955
21988832
22939629
23932992

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0006972  hyperosmotic response
GO:0007585  respiratory gaseous exchange
GO:0014075  response to amine stimulus
GO:0042220  response to cocaine
GO:0051384  response to glucocorticoid stimulus
GO:0070555  response to interleukin-1
GO:0002347  response to tumor cell

Cellular Component

GO:0005737  cytoplasm
GO:0043005  neuron projection
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0046539  histamine N-methyltransferase activity