homeobox A11

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Synonym

HOXA11, homeobox A11, Hox-1I, HOX1I, homeo box A11, Homeobox protein Hox-A11

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:-
GeneChip cerebrum:5.71 cerebellum:5.77 brain stem:5.80 corpus callosum/glia:5.78 pineal gland:- peripheral nerve:5.95 spine:5.80 retina:- eye:- artery/aorta:5.82 vein:6.26 lymphnode:5.68 peripheral blood:- spleen:5.53 thymus:5.57 bone marrow:5.98 adipose:6.05 bone:- skin:5.97
CAGE cerebrum:0.00 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.34 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0.71 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.72 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:36.40 prostate:67.60 ovary:37.30 testis:- heart:- muscle:- esophagus:- stomach:21.20 intestine:- colon:17     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:8.31 placenta:6.53 prostate:6.47 ovary:5.56 testis:5.88 heart:5.64 muscle:6.19 esophagus:5.61 stomach:5.69 intestine:5.70 colon:6.94 liver/hepato:5.87 lung:5.57 bladder:- kidney:6.16 pituitary:5.89 thyroid/parathyroid:5.67 adrenal gland:5.87 pancreas:6.02 breast:5.62 salivary:5.68
CAGE uterus:4.55 placenta:2.83 prostate:3.50 ovary:1.46 testis:1.30 heart:0.09 muscle:1.97 esophagus:0 stomach:- intestine:0.07 colon:3.15     liver/hepato:0    lung:0.05 bladder:3.62 kidney:2.00 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:1.53 salivary:0
RNA-seq uterus:- placenta:- prostate:3.01 ovary:0.09 testis:0.95 heart:0 muscle:1.31 esophagus:- stomach:- intestine:- colon:2.83     liver/hepato:0        lung:0.04    bladder:- kidney:1.91 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.29 pancreas:- breast:0.16 salivary:-

Gene Information

IDs

Refseq ID NM_005523
Gene ID 3207
Unigene ID Hs.249171
Probe set ID 213823_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000005073
GTEx ID ENSG00000005073

Orthologous Gene

Mouse[1]  NM_010450
Rat [0]  

Chromosomal Region

7p15.2  [27,221,129  -  27,224,842]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

1358459
1973146
2574852
8570656
8646877
9745033
10084606
11101832
11299969
11396649
11585930
11830496
11841440
11857506
11937757
12050232
12060755
12477932
12690205
12853948
14973489
15167850
15260975
15467538
15489334
15617687
15674412
15731295
16087734
16963455
18029348
18274672
19255789
19372592
19453261
19609949
19727442
19938081
20457539
20695189
21526497
21890473
21987111
21988832
22233680
22251480
23624749

Gene Ontology  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0009952  anterior/posterior pattern formation
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0060351  cartilage development involved in endochondral bone morphogenesis
GO:0048589  developmental growth
GO:0009953  dorsal/ventral pattern formation
GO:0042733  embryonic digit morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0060272  embryonic skeletal joint morphogenesis
GO:0001759  induction of an organ
GO:0007501  mesodermal cell fate specification
GO:0001656  metanephros development
GO:0007275  multicellular organismal development
GO:0010720  positive regulation of cell development
GO:0032332  positive regulation of chondrocyte differentiation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0009954  proximal/distal pattern formation
GO:0001501  skeletal system development
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0043234  protein complex
GO:0032993  protein-DNA complex
GO:0005667  transcription factor complex

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity