homeobox D11

 jump to detail

Synonym

homeobox D11, Hox-4F, HOXD11, HOX4F, Homeobox protein Hox-D11, homeo box D11

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.59 cerebellum:4.76 brain stem:4.62 corpus callosum/glia:4.70 pineal gland:- peripheral nerve:4.51 spine:4.54 retina:- eye:- artery/aorta:4.45 vein:4.83 lymphnode:4.55 peripheral blood:- spleen:4.42 thymus:4.64 bone marrow:4.74 adipose:4.50 bone:- skin:4.60
CAGE cerebrum:0.00 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0.09 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:0.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:3.60 prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.13 placenta:4.46 prostate:5.42 ovary:4.62 testis:4.43 heart:4.56 muscle:4.68 esophagus:4.49 stomach:4.49 intestine:4.66 colon:5.51 liver/hepato:4.56 lung:4.53 bladder:- kidney:5.29 pituitary:4.54 thyroid/parathyroid:4.40 adrenal gland:4.47 pancreas:4.76 breast:4.48 salivary:4.60
CAGE uterus:3.56 placenta:1.73 prostate:2.74 ovary:0.95 testis:0.43 heart:0.09 muscle:0.66 esophagus:0.09 stomach:- intestine:0 colon:2.09     liver/hepato:0    lung:0 bladder:2.34 kidney:1.91 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.76 ovary:0.01 testis:0.47 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:1.18     liver/hepato:0        lung:0    bladder:- kidney:1.63 pituitary:- thyroid/parathyroid:0 adrenal gland:0.08 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_021192
Gene ID 3237
Unigene ID Hs.421136
Probe set ID 214604_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000128713
GTEx ID ENSG00000128713

Orthologous Gene

Mouse[1]  NM_008273
Rat[1]  NM_008273

Chromosomal Region

2q31.1  [176,968,944  -  176,974,722]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

1358459
1973146
2574852
8890171
9323126
9343407
10075849
10364522
11060466
11493536
11778160
11782354
11857506
12217321
12357469
12477932
17236141
19255789
19453261
19540081
19938081
20085705

Gene Ontology  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0060351  cartilage development involved in endochondral bone morphogenesis
GO:0048589  developmental growth
GO:0009953  dorsal/ventral pattern formation
GO:0042733  embryonic digit morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0060272  embryonic skeletal joint morphogenesis
GO:0001759  induction of an organ
GO:0001656  metanephros development
GO:0010720  positive regulation of cell development
GO:0032332  positive regulation of chondrocyte differentiation
GO:0009954  proximal/distal pattern formation
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity