hypoxanthine phosphoribosyltransferase 1

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Synonym

HGPRTase, Hypoxanthine-guanine phosphoribosyltransferase, HPRT1, HPRT, HGPRT

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:43.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:112.30

retina:-

eye:35.30

artery/aorta:-

vein:66.60

lymphnode:111.20

peripheral blood:54.70

spleen:56.70

thymus:-

bone marrow:19.70

adipose:40.30

bone:-

skin:43.20

GeneChip

cerebrum:8.19

cerebellum:8.27

brain stem:8.48

corpus callosum/glia:6.16

pineal gland:-

peripheral nerve:7.92

spine:7.17

retina:-

eye:-

artery/aorta:6.47

vein:6.67

lymphnode:7.01

peripheral blood:-

spleen:6.86

thymus:8.20

bone marrow:7.88

adipose:6.41

bone:-

skin:6.91

CAGE

cerebrum:4.29

cerebellum:-

brain stem:3.75

corpus callosum/glia:3.02

pineal gland:5.11

peripheral nerve:-

spine:3.46

retina:-

eye:-

artery/aorta:3.44

vein:3.12

lymphnode:3.60

peripheral blood:-

spleen:3.36

thymus:3.64

bone marrow:-

adipose:3.07

bone:-

skin:-

RNA-seq

cerebrum:5.89

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.79

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.67

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:10.90

prostate:11.30

ovary:-

testis:64.90

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:17

liver/hepato:-

lung:9.80

bladder:-

kidney:72.80

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:-

pancreas:124.50

breast:65.10

salivary:-

GeneChip

uterus:7.14

placenta:5.94

prostate:7.46

ovary:7.41

testis:9.46

heart:6.99

muscle:6.94

esophagus:7.07

stomach:7.02

intestine:7.20

colon:7.42

liver/hepato:7.16

lung:6.55

bladder:-

kidney:7.76

pituitary:7.85

thyroid/parathyroid:7.21

adrenal gland:7.04

pancreas:7.56

breast:6.79

salivary:6.47

CAGE

uterus:3.07

placenta:2.62

prostate:3.09

ovary:3.49

testis:4.80

heart:3.32

muscle:3.58

esophagus:3.15

stomach:-

intestine:3.38

colon:3.19

liver/hepato:3.44

lung:3.29

bladder:3.39

kidney:3.79

pituitary:4.09

thyroid/parathyroid:3.41

adrenal gland:-

pancreas:3.77

breast:2.99

salivary:2.75

RNA-seq

uterus:-

placenta:-

prostate:3.96

ovary:4.76

testis:5.98

heart:3.32

muscle:3.49

esophagus:-

stomach:-

intestine:-

colon:3.96

liver/hepato:3.33

lung:4.37

bladder:-

kidney:5.22

pituitary:-

thyroid/parathyroid:4.61

adrenal gland:4.28

pancreas:-

breast:3.52

salivary:-

IDs

Refseq ID	NM_000194
Gene ID	3251
Unigene ID	Hs.412707
Probe set ID	202854_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000165704
GTEx ID	ENSG00000165704

Orthologous Gene

Mouse[1]	NM_013556
Rat [0]

Chromosomal Region

Xq26.2 [133,594,183 - 133,654,543]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006168	adenine salvage
GO:0007610	behavior
GO:0021954	central nervous system neuron development
GO:0021895	cerebral cortex neuron differentiation
GO:0019835	cytolysis
GO:0048813	dendrite morphogenesis
GO:0042417	dopamine metabolic process
GO:0046038	GMP catabolic process
GO:0032263	GMP salvage
GO:0007625	grooming behavior
GO:0006178	guanine salvage
GO:0046100	hypoxanthine metabolic process
GO:0043103	hypoxanthine salvage
GO:0046040	IMP metabolic process
GO:0032264	IMP salvage
GO:0046651	lymphocyte proliferation
GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
GO:0045964	positive regulation of dopamine metabolic process
GO:0051289	protein homotetramerization
GO:0006144	purine base metabolic process
GO:0006164	purine nucleotide biosynthetic process
GO:0006166	purine ribonucleoside salvage
GO:0043101	purine salvage
GO:0001975	response to amphetamine
GO:0021756	striatum development

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol

Molecular Function

GO:0004422	hypoxanthine phosphoribosyltransferase activity
GO:0000287	magnesium ion binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

hypoxanthine phosphoribosyltransferase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function