ArfGAP with FG repeats 1

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Synonym

Rev/Rex activation domain-binding protein, RAB, MGC116940, HIV-1 Rev-binding protein, Nucleoporin-like protein RIP, HIV-1 Rev binding protein, HRB, MGC116938, Rev-interacting protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:17.80 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:17.60 artery/aorta:- vein:- lymphnode:40.40 peripheral blood:18.20 spleen:- thymus:12.90 bone marrow:- adipose:- bone:- skin:19.20
GeneChip cerebrum:6.42 cerebellum:6.12 brain stem:6.26 corpus callosum/glia:6.53 pineal gland:- peripheral nerve:6.29 spine:6.63 retina:- eye:- artery/aorta:6.44 vein:6.58 lymphnode:6.74 peripheral blood:- spleen:6.49 thymus:6.54 bone marrow:7.10 adipose:6.69 bone:- skin:6.57
CAGE cerebrum:4.19 cerebellum:- brain stem:4.21 corpus callosum/glia:4.42 pineal gland:4.22 peripheral nerve:- spine:4.42 retina:- eye:- artery/aorta:3.89 vein:4.08 lymphnode:4.29 peripheral blood:- spleen:4.15 thymus:4.08 bone marrow:- adipose:4.57 bone:- skin:-
RNA-seq cerebrum:1.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.40 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.18 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:14.60 prostate:45.10 ovary:- testis:34.60 heart:25.50 muscle:- esophagus:- stomach:21.20 intestine:- colon:8.50     liver/hepato:-        lung:14.70    bladder:125.60 kidney:- pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:35.60 breast:18.60 salivary:-
GeneChip uterus:6.28 placenta:7.28 prostate:6.38 ovary:6.41 testis:8.57 heart:6.52 muscle:6.50 esophagus:6.15 stomach:6.31 intestine:6.42 colon:6.37 liver/hepato:6.31 lung:6.85 bladder:- kidney:6.42 pituitary:5.66 thyroid/parathyroid:6.50 adrenal gland:6.37 pancreas:5.53 breast:6.63 salivary:5.84
CAGE uterus:3.65 placenta:4.53 prostate:3.67 ovary:4.00 testis:4.46 heart:4.14 muscle:3.77 esophagus:3.88 stomach:- intestine:4.29 colon:3.99     liver/hepato:4.02    lung:4.17 bladder:4.07 kidney:4.05 pituitary:3.67 thyroid/parathyroid:3.69 adrenal gland:- pancreas:3.67 breast:4.49 salivary:3.15
RNA-seq uterus:- placenta:- prostate:0.76 ovary:0.79 testis:0.78 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.72     liver/hepato:0.54        lung:1.57    bladder:- kidney:1.17 pituitary:- thyroid/parathyroid:1.35 adrenal gland:1.01 pancreas:- breast:1.18 salivary:-

Gene Information

IDs

Refseq ID NM_001135188
Gene ID 3267
Unigene ID Hs.352962
Probe set ID 218091_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000173744
GTEx ID ENSG00000173744

Orthologous Gene

Mouse[8]  NM_010472
Rat [0]  

Chromosomal Region

2q36.3  [228,336,868  -  228,421,384]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7634337
7637788
8195203
8633082
8805303
8943370
9070945
9303539
9368759
9500467
10358091
10613896
10737800
11062555
11545741
11854271
12429849
12477932
14554087
14701878
14702039
15489334
15749819
15815621
16354571
16903783
17081983
18029348
18775314
18819912
19149558
19149559
19262425
19738201
20936779
21118098
21139048
21358275
21360055
21439320
21752912
21832049
21906983
22558309
22623428
22863883
22939629
23000965
23984888
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0006406  mRNA export from nucleus
GO:0007275  multicellular organismal development
GO:0032312  regulation of ARF GTPase activity
GO:0007283  spermatogenesis

Cellular Component

GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0005643  nuclear pore

Molecular Function

GO:0008060  ARF GTPase activator activity
GO:0003677  DNA binding
GO:0005515  protein binding
GO:0003723  RNA binding
GO:0008270  zinc ion binding