heat shock 70kDa protein 1B

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:9.83 cerebellum:10.25 brain stem:10.06 corpus callosum/glia:11.45 pineal gland:- peripheral nerve:11.58 spine:11.61 retina:- eye:- artery/aorta:11.76 vein:11.10 lymphnode:10.70 peripheral blood:- spleen:11.23 thymus:10.70 bone marrow:11.42 adipose:11.07 bone:- skin:10
CAGE cerebrum:1.92 cerebellum:- brain stem:1.97 corpus callosum/glia:1.33 pineal gland:1.67 peripheral nerve:- spine:2.83 retina:- eye:- artery/aorta:4.12 vein:1.65 lymphnode:0.77 peripheral blood:- spleen:0.56 thymus:0.18 bone marrow:- adipose:1.01 bone:- skin:-
RNA-seq cerebrum:5.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:9.78 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.61 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:10.57 placenta:8.92 prostate:10.84 ovary:10.69 testis:9.29 heart:10.76 muscle:10.27 esophagus:11.27 stomach:10.90 intestine:10.02 colon:10.15 liver/hepato:10.83 lung:12.33 bladder:- kidney:10.71 pituitary:9.32 thyroid/parathyroid:11.08 adrenal gland:10.69 pancreas:9.18 breast:9.91 salivary:10.26
CAGE uterus:1.61 placenta:1.61 prostate:2.60 ovary:0.89 testis:1.32 heart:3.16 muscle:2.13 esophagus:2.99 stomach:- intestine:0.48 colon:2.17     liver/hepato:0.63    lung:2.97 bladder:2.63 kidney:1.60 pituitary:1.72 thyroid/parathyroid:2.70 adrenal gland:- pancreas:1.98 breast:3.58 salivary:1.28
RNA-seq uterus:- placenta:- prostate:7.09 ovary:6.85 testis:6.72 heart:4.50 muscle:4.75 esophagus:- stomach:- intestine:- colon:9.67     liver/hepato:3.31        lung:8.27    bladder:- kidney:6.62 pituitary:- thyroid/parathyroid:9.14 adrenal gland:4.38 pancreas:- breast:6.73 salivary:-

Gene Information

IDs

Refseq ID NM_005346
Gene ID 3304
Unigene ID -
Probe set ID 200800_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204388
ENSG00000231555
GTEx ID ENSG00000204388
ENSG00000231555

Orthologous Gene

Mouse[4]  NM_010478, NM_010479
Rat [0]  

Chromosomal Region

HSCHR6_MHC_APD  [31,794,605  -  31,797,087]
HSCHR6_MHC_APD  [31,806,879  -  31,809,393]
HSCHR6_MHC_QBL  [31,773,491  -  31,775,973]
HSCHR6_MHC_QBL  [31,785,766  -  31,788,290]
HSCHR6_MHC_COX  [31,770,617  -  31,773,099]
HSCHR6_MHC_COX  [31,782,890  -  31,785,413]
6p21.33  [31,783,291  -  31,785,723]
6p21.33  [31,795,512  -  31,798,031]
HSCHR6_MHC_DBB  [31,765,431  -  31,767,913]
HSCHR6_MHC_DBB  [31,777,702  -  31,780,222]

Gene Family (Interpro ID)

IPR001023  Heat shock protein Hsp70

Link to Pubmed  (Pubmed ID)

1478667
1700760
2538825
2858050
2880793
3019832
3470951
3786141
3931075
7906708
9553041
10205060
10216320
10617616
10859165
10964507
11231577
11533664
11696222
11730740
11779758
11864979
11932435
11971973
12008944
12082592
12207910
12391142
12411538
12477932
12490434
12544996
12691826
12703993
12730033
12832005
12853476
12967056
14506234
14574404
14605873
14656967
15165109
15223990
15232679
15236755
15324660
15489334
15492215
15603737
15671022
15714129
15748471
15885686
15963462
15963589
15992611
16130169
16165702
16169070
16202503
16236267
16275660
16333988
16344560
16441767
16525348
16713569
16804002
16953332
16964243
17081983
17158748
17167422
17289661
17301649
17311111
17314700
17342744
17364813
17428599
17532782
17558451
17582394
17620599
17940904
18191480
18299791
18344806
18478330
18518860
18529014
18551993
18580445
18759004
18813331
18818748
18822209
18844219
18850735
18975920
18987644
19019335
19046306
19085089
19199708
19275587
19287380
19299493
19322201
19335985
19351530
19380743
19439993
19527514
19596686
19626584
19643584
19661373
19731315
19738201
19754858
19759913
19840767
19851445
20012387
20043082
20140262
20207250
20388090
20498198
20568452
20587610
20639865
20692469
20704535
20714140
20876613
20972266
21139048
21145461
21360678
21373891
21471543
21487019
21693764
21738007
21738476
21763498
21890473
21906983
21963094
21970979
21987572
21988832
22037874
22053931
22160620
22268729
22323290
22468780
22505724
22623428
22797398
22834788
22883735
22922572
23000965
23065205
23125841
23182705
23184937
23246001
23330093
23349634
23425104
23490384
23666708
23798571
23862649
23874968
23885119
24399297
24457600
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0010467  gene expression
GO:0006402  mRNA catabolic process
GO:0016071  mRNA metabolic process
GO:0043066  negative regulation of apoptosis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0090084  negative regulation of inclusion body assembly
GO:0045648  positive regulation of erythrocyte differentiation
GO:0042026  protein refolding
GO:0006986  response to unfolded protein
GO:0016070  RNA metabolic process

Cellular Component

GO:0016235  aggresome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0016234  inclusion body
GO:0005739  mitochondrion
GO:0016607  nuclear speck
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0030529  ribonucleoprotein complex
GO:0008180  signalosome

Molecular Function

GO:0005524  ATP binding
GO:0005515  protein binding
GO:0044183  protein binding involved in protein folding
GO:0047485  protein N-terminus binding
GO:0031625  ubiquitin protein ligase binding
GO:0051082  unfolded protein binding