heat shock protein 90kDa alpha (cytosolic), class B member 1

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Synonym

HSP90-BETA, HSP 90, HSP90AB1, HSPC2, HSP90B, Heat shock protein HSP 90-beta, FLJ26984, D6S182, HSP 84, HSPCB

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1692.40

cerebellum:1032.70

brain stem:-

corpus callosum/glia:2712

pineal gland:593.40

peripheral nerve:828.10

spine:2245.90

retina:1660.90

eye:787.50

artery/aorta:2158.20

vein:1199.70

lymphnode:576.30

peripheral blood:1111.30

spleen:1720.50

thymus:979.20

bone marrow:295.20

adipose:1815

bone:1036.40

skin:1017.60

GeneChip

cerebrum:9.15

cerebellum:9.22

brain stem:9.43

corpus callosum/glia:8.50

pineal gland:-

peripheral nerve:9.57

spine:8.94

retina:-

eye:-

artery/aorta:8.27

vein:8.19

lymphnode:7.86

peripheral blood:-

spleen:8.13

thymus:9.02

bone marrow:7.73

adipose:8.39

bone:-

skin:8.45

CAGE

cerebrum:7.12

cerebellum:-

brain stem:7.38

corpus callosum/glia:6.69

pineal gland:6.87

peripheral nerve:-

spine:7.14

retina:-

eye:-

artery/aorta:7.06

vein:6.67

lymphnode:6.69

peripheral blood:-

spleen:6.59

thymus:6.44

bone marrow:-

adipose:6.89

bone:-

skin:-

RNA-seq

cerebrum:8.65

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:8.67

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:8.13

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:1221.20

placenta:386.20

prostate:1058.90

ovary:1788.60

testis:545.10

heart:791.80

muscle:1024.60

esophagus:1371.30

stomach:467.30

intestine:1360.70

colon:1051.50

liver/hepato:791.70

lung:884.60

bladder:2386.60

kidney:551.10

pituitary:232

thyroid/parathyroid:2292.50

adrenal gland:1726.80

pancreas:142.30

breast:1347.50

salivary:985.20

GeneChip

uterus:9.34

placenta:8.05

prostate:9.82

ovary:9.88

testis:8.44

heart:8.60

muscle:8.99

esophagus:8.63

stomach:8.24

intestine:8.59

colon:8.51

liver/hepato:7.39

lung:8.56

bladder:-

kidney:8.07

pituitary:8.98

thyroid/parathyroid:8.23

adrenal gland:8.37

pancreas:9.13

breast:8.53

salivary:8.28

CAGE

uterus:7.09

placenta:6.41

prostate:7.14

ovary:7.48

testis:6.57

heart:6.89

muscle:7.35

esophagus:6.75

stomach:-

intestine:6.04

colon:6.28

liver/hepato:6.64

lung:6.61

bladder:7.02

kidney:6.71

pituitary:7.15

thyroid/parathyroid:7.37

adrenal gland:-

pancreas:7.15

breast:7.26

salivary:6.75

RNA-seq

uterus:-

placenta:-

prostate:8.66

ovary:9.32

testis:8.50

heart:7.38

muscle:8.48

esophagus:-

stomach:-

intestine:-

colon:9.28

liver/hepato:6.69

lung:8.83

bladder:-

kidney:8.10

pituitary:-

thyroid/parathyroid:9.33

adrenal gland:8.01

pancreas:-

breast:8.02

salivary:-

IDs

Refseq ID	NM_007355
Gene ID	3326
Unigene ID	Hs.509736
Probe set ID	214359_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000096384
GTEx ID	ENSG00000096384

Orthologous Gene

Mouse[2]	NM_008302
Rat [0]

Chromosomal Region

6p21.1 [44,214,824 - 44,221,620]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003594	ATPase-like, ATP-binding domain
IPR001404	Chaperone protein htpG
IPR020575	Heat shock protein Hsp90, N-terminal

Gene Ontology (GO ID)

Biological Process

GO:0007411	axon guidance
GO:0071353	cellular response to interleukin-4
GO:0071407	cellular response to organic cyclic substance
GO:0045087	innate immune response
GO:0043524	negative regulation of neuron apoptosis
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001890	placenta development
GO:0045793	positive regulation of cell size
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0032092	positive regulation of protein binding
GO:0033160	positive regulation of protein import into nucleus, translocation
GO:0006457	protein folding
GO:0060334	regulation of interferon-gamma-mediated signaling pathway
GO:0060338	regulation of type I interferon-mediated signaling pathway
GO:0009651	response to salt stress
GO:0006986	response to unfolded protein

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0031526	brush border membrane
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016234	inclusion body
GO:0042470	melanosome
GO:0005739	mitochondrion
GO:0008180	signalosome

Molecular Function

GO:0005524	ATP binding
GO:0002135	CTP binding
GO:0032564	dATP binding
GO:0005525	GTP binding
GO:0030235	nitric-oxide synthase regulator activity
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0017098	sulfonylurea receptor binding
GO:0030911	TPR domain binding
GO:0051082	unfolded protein binding
GO:0002134	UTP binding

heat shock protein 90kDa alpha (cytosolic), class B member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function