forkhead box N2

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Synonym

human T-cell leukemia virus enhancer factor, forkhead box N2, HTLF, Human T-cell leukemia virus enhancer factor, Forkhead box protein N2, FOXN2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:21.30 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:50.60 peripheral blood:72.90 spleen:- thymus:38.70 bone marrow:- adipose:- bone:- skin:52.80
GeneChip cerebrum:3.61 cerebellum:3.59 brain stem:3.74 corpus callosum/glia:3.72 pineal gland:- peripheral nerve:3.78 spine:3.64 retina:- eye:- artery/aorta:3.79 vein:3.78 lymphnode:3.73 peripheral blood:- spleen:3.70 thymus:3.44 bone marrow:4.15 adipose:3.83 bone:- skin:3.54
CAGE cerebrum:3.69 cerebellum:- brain stem:4.27 corpus callosum/glia:4.43 pineal gland:3.51 peripheral nerve:- spine:4.16 retina:- eye:- artery/aorta:2.89 vein:3.58 lymphnode:3.69 peripheral blood:- spleen:4.04 thymus:3.90 bone marrow:- adipose:4.11 bone:- skin:-
RNA-seq cerebrum:3.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.27 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.30 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:51 prostate:- ovary:186.30 testis:13 heart:- muscle:40.20 esophagus:- stomach:- intestine:- colon:93.30     liver/hepato:52.80        lung:34.20    bladder:125.60 kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:46.50 salivary:-
GeneChip uterus:3.51 placenta:3.92 prostate:3.34 ovary:3.58 testis:3.38 heart:3.61 muscle:3.60 esophagus:3.40 stomach:3.62 intestine:3.57 colon:3.48 liver/hepato:3.76 lung:3.64 bladder:- kidney:3.37 pituitary:3.71 thyroid/parathyroid:3.55 adrenal gland:3.70 pancreas:3.31 breast:3.50 salivary:3.28
CAGE uterus:3.18 placenta:3.66 prostate:3.20 ovary:2.83 testis:2.68 heart:3.12 muscle:2.88 esophagus:3.18 stomach:- intestine:3.33 colon:2.98     liver/hepato:3.20    lung:3.54 bladder:3.65 kidney:3.05 pituitary:3.31 thyroid/parathyroid:2.79 adrenal gland:- pancreas:2.81 breast:3.87 salivary:2.63
RNA-seq uterus:- placenta:- prostate:3.08 ovary:2.06 testis:2.85 heart:2.11 muscle:2.83 esophagus:- stomach:- intestine:- colon:2.39     liver/hepato:2.16        lung:2.79    bladder:- kidney:2.55 pituitary:- thyroid/parathyroid:2.34 adrenal gland:3.00 pancreas:- breast:3.56 salivary:-

Gene Information

IDs

Refseq ID NM_002158
Gene ID 3344
Unigene ID Hs.468478
Probe set ID 206708_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000170802
GTEx ID ENSG00000170802

Orthologous Gene

Mouse[2]  NM_180974
Rat[2]  NM_180974

Chromosomal Region

2p16.3  [48,541,776  -  48,606,434]

Gene Family (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

1639393
12477932
14702039
18029348
19322201
20379614
21531217
21845734

Gene Ontology  (GO ID)

Biological Process

GO:0009790  embryonic development
GO:0007389  pattern specification process
GO:0051090  regulation of transcription factor activity
GO:0009888  tissue development

Cellular Component

GO:0043231  intracellular membrane-bounded organelle
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding