inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

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Synonym

MGC26389, ID2A, ID2, GIG8, ID2H, Inhibitor of DNA binding 2, DNA-binding protein inhibitor ID-2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:107.80

cerebellum:63

brain stem:-

corpus callosum/glia:58.30

pineal gland:148.30

peripheral nerve:153.40

spine:224.60

retina:118.60

eye:94

artery/aorta:89.90

vein:-

lymphnode:91

peripheral blood:36.40

spleen:-

thymus:25.80

bone marrow:59

adipose:242

bone:102.40

skin:81.60

GeneChip

cerebrum:8.60

cerebellum:7.89

brain stem:7.97

corpus callosum/glia:8.89

pineal gland:-

peripheral nerve:8.54

spine:9.67

retina:-

eye:-

artery/aorta:10.21

vein:10.22

lymphnode:8.93

peripheral blood:-

spleen:9.80

thymus:8.79

bone marrow:8.97

adipose:9.13

bone:-

skin:8.81

CAGE

cerebrum:5.29

cerebellum:-

brain stem:4.55

corpus callosum/glia:5.34

pineal gland:3.61

peripheral nerve:-

spine:5.15

retina:-

eye:-

artery/aorta:6.88

vein:5.12

lymphnode:4.83

peripheral blood:-

spleen:4.95

thymus:4.95

bone marrow:-

adipose:5.30

bone:-

skin:-

RNA-seq

cerebrum:5.79

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.75

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.27

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:40.10

prostate:45.10

ovary:149.10

testis:38.90

heart:229.90

muscle:20.10

esophagus:-

stomach:42.50

intestine:97.20

colon:59.40

liver/hepato:253.30

lung:176

bladder:251.20

kidney:104

pituitary:116

thyroid/parathyroid:163.70

adrenal gland:203.10

pancreas:168.90

breast:83.60

salivary:-

GeneChip

uterus:9.33

placenta:7.11

prostate:10.20

ovary:9.39

testis:6.59

heart:8.95

muscle:5.28

esophagus:8.31

stomach:9.02

intestine:8.38

colon:9.27

liver/hepato:10.49

lung:9.58

bladder:-

kidney:9.72

pituitary:8.35

thyroid/parathyroid:10.04

adrenal gland:10.08

pancreas:7.10

breast:9.09

salivary:9.29

CAGE

uterus:5.25

placenta:4.33

prostate:5.51

ovary:6.26

testis:4.02

heart:5.36

muscle:4.28

esophagus:4.70

stomach:-

intestine:5.13

colon:5.58

liver/hepato:6.70

lung:5.41

bladder:5.62

kidney:5.57

pituitary:4.46

thyroid/parathyroid:4.89

adrenal gland:-

pancreas:4.75

breast:5.69

salivary:5.51

RNA-seq

uterus:-

placenta:-

prostate:6.51

ovary:7.30

testis:5.33

heart:4.06

muscle:3.28

esophagus:-

stomach:-

intestine:-

colon:5.89

liver/hepato:6.67

lung:5.76

bladder:-

kidney:6.05

pituitary:-

thyroid/parathyroid:5.32

adrenal gland:5.77

pancreas:-

breast:4.90

salivary:-

IDs

Refseq ID	NM_002166
Gene ID	3398
Unigene ID	Hs.180919
Probe set ID	201565_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000115738
GTEx ID	ENSG00000115738

Orthologous Gene

Mouse[4]	NM_010496
Rat [0]

Chromosomal Region

2p25.1 [8,818,975 - 8,824,583]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0060612	adipose tissue development
GO:0003166	bundle of His development
GO:0048469	cell maturation
GO:0071285	cellular response to lithium ion
GO:0048557	embryonic digestive tract morphogenesis
GO:0009649	entrainment of circadian clock
GO:0043353	enucleate erythrocyte differentiation
GO:0060749	mammary gland alveolus development
GO:0033598	mammary gland epithelial cell proliferation
GO:0003149	membranous septum morphogenesis
GO:0001656	metanephros development
GO:0007275	multicellular organismal development
GO:0001779	natural killer cell differentiation
GO:0045578	negative regulation of B cell differentiation
GO:0043392	negative regulation of DNA binding
GO:0010629	negative regulation of gene expression
GO:0045665	negative regulation of neuron differentiation
GO:0048715	negative regulation of oligodendrocyte differentiation
GO:0045668	negative regulation of osteoblast differentiation
GO:0043433	negative regulation of transcription factor activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0048663	neuron fate commitment
GO:0021772	olfactory bulb development
GO:0014003	oligodendrocyte development
GO:0048541	Peyer's patch development
GO:0048711	positive regulation of astrocyte differentiation
GO:0045777	positive regulation of blood pressure
GO:0045787	positive regulation of cell cycle
GO:0071158	positive regulation of cell cycle arrest
GO:0045648	positive regulation of erythrocyte differentiation
GO:0045600	positive regulation of fat cell differentiation
GO:0010628	positive regulation of gene expression
GO:0045651	positive regulation of macrophage differentiation
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0019216	regulation of lipid metabolic process

Cellular Component

GO:0000785	chromatin
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0043234	protein complex

Molecular Function

GO:0005515	protein binding
GO:0046983	protein dimerization activity

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function