nuclear receptor binding protein 2

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Synonym

pp9320, PP9320, Nuclear receptor-binding protein 2, nuclear receptor binding protein 2, NRBP2, Transformation-related protein 16, DKFZp434P086, MGC138699

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.70 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:112.30 retina:- eye:17.60 artery/aorta:60 vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:25.60 skin:28.80
GeneChip nodata
CAGE nodata
RNA-seq cerebrum:3.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.05 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.38 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:7.30 prostate:33.80 ovary:37.30 testis:4.30 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:10.60        lung:19.60    bladder:- kidney:83.20 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:9.30 salivary:-
GeneChip nodata
CAGE nodata
RNA-seq uterus:- placenta:- prostate:3.35 ovary:2.83 testis:2.14 heart:1.97 muscle:1.02 esophagus:- stomach:- intestine:- colon:2.44     liver/hepato:3.35        lung:3.15    bladder:- kidney:3.25 pituitary:- thyroid/parathyroid:1.93 adrenal gland:2.01 pancreas:- breast:3.30 salivary:-

Gene Information

IDs

Refseq ID NM_178564
Gene ID 340371
Unigene ID Hs.521926
Probe set ID -
Ensembl ID ENSG00000185189
GTEx ID ENSG00000185189

Orthologous Gene

Mouse[1]  NM_144847
Rat[1]  NM_001135007

Chromosomal Region

8q24.3  [144,915,764  -  144,924,200]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

12477932
14702039
15489334
15498874
18619852

Gene Ontology  (GO ID)

Biological Process

GO:0016242  negative regulation of macroautophagy
GO:0043524  negative regulation of neuron apoptosis
GO:0030182  neuron differentiation
GO:0006468  protein amino acid phosphorylation

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0000166  nucleotide binding
GO:0004672  protein kinase activity