apolipoprotein C-I

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Synonym

Apo-CI, ApoC-I, Apolipoprotein C-I precursor, APOC1, apolipoprotein C-I

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:449.20 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:741.70 peripheral nerve:306.70 spine:561.50 retina:- eye:387.90 artery/aorta:209.80 vein:- lymphnode:131.40 peripheral blood:473.70 spleen:397 thymus:51.50 bone marrow:39.40 adipose:201.70 bone:166.30 skin:484.80
GeneChip cerebrum:7.61 cerebellum:6.36 brain stem:8.21 corpus callosum/glia:7.46 pineal gland:- peripheral nerve:7.57 spine:7.38 retina:- eye:- artery/aorta:6.24 vein:5.90 lymphnode:8.40 peripheral blood:- spleen:7.89 thymus:7.09 bone marrow:7.61 adipose:7.54 bone:- skin:7.20
CAGE cerebrum:1.62 cerebellum:- brain stem:2.19 corpus callosum/glia:1.74 pineal gland:0.97 peripheral nerve:- spine:2.70 retina:- eye:- artery/aorta:0.59 vein:0.79 lymphnode:0.91 peripheral blood:- spleen:1.46 thymus:0.50 bone marrow:- adipose:0.78 bone:- skin:-
RNA-seq cerebrum:4.65 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.50 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.41 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:145.80 placenta:455.40 prostate:371.70 ovary:372.60 testis:190.40 heart:242.70 muscle:60.30 esophagus:- stomach:701 intestine:64.80 colon:330.70     liver/hepato:950        lung:376.30    bladder:125.60 kidney:717.40 pituitary:- thyroid/parathyroid:- adrenal gland:1371.30 pancreas:249 breast:325.30 salivary:-
GeneChip uterus:6.15 placenta:6.72 prostate:5.68 ovary:7.68 testis:6.15 heart:6.39 muscle:6.21 esophagus:5.99 stomach:6.66 intestine:7.14 colon:6.35 liver/hepato:13.24 lung:10.08 bladder:- kidney:5.95 pituitary:6.17 thyroid/parathyroid:6.40 adrenal gland:11.05 pancreas:6.62 breast:7.83 salivary:6.18
CAGE uterus:0.13 placenta:0.68 prostate:0.27 ovary:1.62 testis:0.40 heart:0.03 muscle:0.25 esophagus:0 stomach:- intestine:0.53 colon:0.48     liver/hepato:3.89    lung:1.88 bladder:0.40 kidney:0 pituitary:0.90 thyroid/parathyroid:0.32 adrenal gland:- pancreas:0.58 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:4.28 ovary:5.07 testis:4.47 heart:1.40 muscle:3.78 esophagus:- stomach:- intestine:- colon:4.26     liver/hepato:12.23        lung:7.92    bladder:- kidney:1.61 pituitary:- thyroid/parathyroid:3.30 adrenal gland:5.55 pancreas:- breast:4.39 salivary:-

IDs

Refseq ID NM_001645
Gene ID 341
Unigene ID Hs.110675
Probe set ID 204416_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130208
GTEx ID ENSG00000130208

Orthologous Gene

Mouse[2]  NM_001110009, NM_007469
Rat[2]  NM_001109996, NM_012824

Chromosomal Region

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0033344  cholesterol efflux
GO:0008203  cholesterol metabolic process
GO:0034382  chylomicron remnant clearance
GO:0034375  high-density lipoprotein particle remodeling
GO:0006629  lipid metabolic process
GO:0042157  lipoprotein metabolic process
GO:0032375  negative regulation of cholesterol transport
GO:0045717  negative regulation of fatty acid biosynthetic process
GO:0050995  negative regulation of lipid catabolic process
GO:0045833  negative regulation of lipid metabolic process
GO:0051005  negative regulation of lipoprotein lipase activity
GO:0010900  negative regulation of phosphatidylcholine catabolic process
GO:0048261  negative regulation of receptor-mediated endocytosis
GO:0010916  negative regulation of very-low-density lipoprotein particle clearance
GO:0033700  phospholipid efflux
GO:0034369  plasma lipoprotein particle remodeling
GO:0010873  positive regulation of cholesterol esterification
GO:0032374  regulation of cholesterol transport
GO:0006641  triglyceride metabolic process
GO:0034379  very-low-density lipoprotein particle assembly
GO:0034447  very-low-density lipoprotein particle clearance

Cellular Component

GO:0042627  chylomicron
GO:0005783  endoplasmic reticulum
GO:0034364  high-density lipoprotein particle
GO:0034361  very-low-density lipoprotein particle

Molecular Function

GO:0005504  fatty acid binding
GO:0055102  lipase inhibitor activity
GO:0031210  phosphatidylcholine binding
GO:0060228  phosphatidylcholine-sterol O-acyltransferase activator activity
GO:0004859  phospholipase inhibitor activity