guanine nucleotide binding protein, alpha transducing 3

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Synonym

gustducin, GDCA, GNAT3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.09 cerebellum:3.10 brain stem:3.17 corpus callosum/glia:3.10 pineal gland:- peripheral nerve:3.17 spine:3.10 retina:- eye:- artery/aorta:3.23 vein:3.19 lymphnode:3.07 peripheral blood:- spleen:3.06 thymus:3 bone marrow:3.23 adipose:3.17 bone:- skin:3.10
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0.03 peripheral blood:- spleen:0 thymus:0.12 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.12 placenta:3.05 prostate:3.04 ovary:3.08 testis:3.07 heart:3.07 muscle:3.13 esophagus:3.10 stomach:3.08 intestine:3.21 colon:3.15 liver/hepato:3.13 lung:2.94 bladder:- kidney:3.04 pituitary:3.11 thyroid/parathyroid:3.03 adrenal gland:3.01 pancreas:3.30 breast:3.08 salivary:2.99
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:1.78 colon:0.62     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0.18 heart:0.10 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_001102386
Gene ID 346562
Unigene ID Hs.335049
Probe set ID 216590_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000214415
GTEx ID ENSG00000214415

Orthologous Gene

Mouse[1]  NM_001081143
Rat [0]  

Chromosomal Region

7q21.11  [80,087,987  -  80,141,336]

Gene Family (Interpro ID)

IPR001408  G-protein alpha subunit, group I
IPR001019  Guanine nucleotide binding protein (G-protein), alpha subunit

Link to Pubmed  (Pubmed ID)

8015379
8208289
8521505
10570481
11118617
11917125
12477932
12690205
12853948
16728727
16892066
17021831
17724330
17724332
18240029
18468998
20360068
20660057
20858777
21139048
21324568
21890473
21906983
21963094
21987572
22456541
22505724
23000965

Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0001580  detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007188  G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0030168  platelet activation
GO:0035094  response to nicotine
GO:0050916  sensory perception of sweet taste
GO:0050917  sensory perception of umami taste
GO:0007268  synaptic transmission

Cellular Component

GO:0016324  apical plasma membrane
GO:0005737  cytoplasm
GO:0031234  extrinsic to internal side of plasma membrane
GO:0005834  heterotrimeric G-protein complex
GO:0001917  photoreceptor inner segment
GO:0001750  photoreceptor outer segment
GO:0005886  plasma membrane
GO:0043234  protein complex

Molecular Function

GO:0031683  G-protein beta/gamma-subunit binding
GO:0001664  G-protein-coupled receptor binding
GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0046872  metal ion binding
GO:0004871  signal transducer activity