aquaporin 1 (Colton blood group)

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Synonym

AQP-CHIP, CO, Colton blood group, aquaporin 1 (Colton blood group), Urine water channel, Aquaporin-1, CHIP28, AQP1, Aquaporin-CHIP, MGC26324, 28kDa, AQP-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:196.70 cerebellum:176.30 brain stem:- corpus callosum/glia:437.40 pineal gland:296.70 peripheral nerve:674.80 spine:786.10 retina:- eye:129.30 artery/aorta:30 vein:333.20 lymphnode:- peripheral blood:- spleen:56.70 thymus:1082.20 bone marrow:19.70 adipose:726 bone:166.30 skin:124.80
GeneChip cerebrum:6.61 cerebellum:5.70 brain stem:7.46 corpus callosum/glia:7.93 pineal gland:- peripheral nerve:8.11 spine:9.33 retina:- eye:- artery/aorta:8.62 vein:8.25 lymphnode:6.27 peripheral blood:- spleen:5.36 thymus:6.53 bone marrow:7.09 adipose:8.26 bone:- skin:8.15
CAGE cerebrum:3.84 cerebellum:- brain stem:4.53 corpus callosum/glia:5.45 pineal gland:3.60 peripheral nerve:- spine:5.42 retina:- eye:- artery/aorta:6.25 vein:4.93 lymphnode:3.48 peripheral blood:- spleen:2.48 thymus:1.95 bone marrow:- adipose:5.60 bone:- skin:-
RNA-seq cerebrum:4.63 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:7.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.18 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:382.80 placenta:36.40 prostate:292.90 ovary:37.30 testis:17.30 heart:485.30 muscle:241.10 esophagus:342.80 stomach:233.70 intestine:324 colon:67.80     liver/hepato:31.70        lung:454.50    bladder:1256.10 kidney:1143.70 pituitary:- thyroid/parathyroid:163.70 adrenal gland:101.60 pancreas:80 breast:148.70 salivary:-
GeneChip uterus:7.42 placenta:5.34 prostate:7.36 ovary:6.98 testis:4.90 heart:8.75 muscle:7.09 esophagus:7.44 stomach:7.25 intestine:7.60 colon:7.32 liver/hepato:5.79 lung:9.20 bladder:- kidney:9.04 pituitary:5.09 thyroid/parathyroid:6.20 adrenal gland:6.23 pancreas:8.24 breast:7.72 salivary:6.34
CAGE uterus:4.94 placenta:2.42 prostate:4.87 ovary:4.14 testis:3.03 heart:5.15 muscle:4.11 esophagus:5.40 stomach:- intestine:3.99 colon:4.01     liver/hepato:2.69    lung:6.24 bladder:4.92 kidney:5.38 pituitary:2.46 thyroid/parathyroid:4.32 adrenal gland:- pancreas:4.94 breast:5.31 salivary:3.65
RNA-seq uterus:- placenta:- prostate:6.14 ovary:4.48 testis:4.92 heart:5.73 muscle:4.19 esophagus:- stomach:- intestine:- colon:6.92     liver/hepato:2.09        lung:7.39    bladder:- kidney:5.79 pituitary:- thyroid/parathyroid:5.26 adrenal gland:7.22 pancreas:- breast:6.40 salivary:-

Gene Information

IDs

Refseq ID NM_198098
Gene ID 358
Unigene ID Hs.76152
Probe set ID 207542_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000240583
GTEx ID ENSG00000240583

Orthologous Gene

Mouse[1]  NM_007472
Rat [0]  

Chromosomal Region

7p14.3  [30,893,010  -  30,965,131]

Gene Family (Interpro ID)

IPR012269  Aquaporin
IPR000425  Major intrinsic protein

Link to Pubmed  (Pubmed ID)

1373524
1722319
2007592
3049610
3166547
7491270
7507481
7514605
7517253
7517546
7518771
7521540
7521882
7532004
7540589
7544358
7677994
7693713
8340403
8576117
8584435
8703970
9013443
9096382
9177353
9321919
9468475
10559675
10839360
10872456
10873606
11034202
11097616
11171962
11408278
11532455
11780053
11884383
11909995
11914159
11922632
12002613
12027013
12051745
12137754
12172703
12237771
12399631
12477932
12498798
12522663
12690205
12745312
12766090
12781664
12801959
12853948
14514735
14561230
14592814
14675051
14701836
14753493
14753494
15024704
15135660
15326289
15489334
15502805
15563082
15667881
15727941
15783300
15809704
15847654
16133142
16189514
16300893
16344560
16481371
16515633
16534779
16565507
16574458
16682607
16698771
16711029
16814974
16871401
17012249
17077939
17219999
17273788
17408468
17409744
17511167
17545093
17549682
17632520
17636236
17645239
17854859
17890385
17894331
17898873
18052958
18067501
18080132
18202181
18247144
18275976
18280225
18282122
18313673
18349152
18392839
18509662
18510579
18538351
18544259
18563339
18575775
18617525
18665841
18841368
19060904
19080511
19253825
19268465
19273840
19306058
19424603
19447967
19472194
19522191
19545896
19584911
19619954
19670620
19726340
19772916
19787701
19913121
20063900
20101282
20137115
20149606
20360993
20409716
20424473
20431033
20461409
20578142
20628061
20628086
20739606
20795314
20806077
20828513
20965731
20969805
21063116
21107133
21237499
21244858
21252246
21271497
21360438
21373963
21395179
21538271
21551254
21612401
21760919
21784068
21793635
21839760
21896312
22006723
22093331
22269467
22310126
22334691
22348807
22372348
22396660
22472942
22901156
22901921
22964306
23029502
23219802
23220481
23268390
23276695
23313295
23317544
23332061
23361277
23393355
23450058
23549977
23928039
24014128
24493792

Gene Ontology  (GO ID)

Biological Process

GO:0015696  ammonium transport
GO:0015701  bicarbonate transport
GO:0015670  carbon dioxide transport
GO:0006884  cell volume homeostasis
GO:0019725  cellular homeostasis
GO:0071474  cellular hyperosmotic response
GO:0071320  cellular response to cAMP
GO:0071280  cellular response to copper ion
GO:0070301  cellular response to hydrogen peroxide
GO:0071456  cellular response to hypoxia
GO:0071241  cellular response to inorganic substance
GO:0071260  cellular response to mechanical stimulus
GO:0071288  cellular response to mercury ion
GO:0071300  cellular response to retinoic acid
GO:0071472  cellular response to salt stress
GO:0033554  cellular response to stress
GO:0034644  cellular response to UV
GO:0033326  cerebrospinal fluid secretion
GO:0006182  cGMP biosynthetic process
GO:0030950  establishment or maintenance of actin cytoskeleton polarity
GO:0015793  glycerol transport
GO:0021670  lateral ventricle development
GO:0050891  multicellular organismal water homeostasis
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0030185  nitric oxide transport
GO:0042476  odontogenesis
GO:0030157  pancreatic juice secretion
GO:0045766  positive regulation of angiogenesis
GO:0048146  positive regulation of fibroblast proliferation
GO:0046878  positive regulation of saliva secretion
GO:0006813  potassium ion transport
GO:0003097  renal water transport
GO:0042493  response to drug
GO:0055085  transmembrane transport
GO:0006833  water transport

Cellular Component

GO:0045177  apical part of cell
GO:0016324  apical plasma membrane
GO:0009925  basal plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005903  brush border
GO:0031526  brush border membrane
GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane
GO:0031965  nuclear membrane
GO:0005634  nucleus
GO:0020005  parasitophorous vacuolar membrane
GO:0020003  parasitophorous vacuole
GO:0005886  plasma membrane
GO:0042383  sarcolemma

Molecular Function

GO:0051739  ammonia transporter activity
GO:0015168  glycerol transmembrane transporter activity
GO:0005223  intracellular cGMP activated cation channel activity
GO:0030184  nitric oxide transporter activity
GO:0005267  potassium channel activity
GO:0015079  potassium ion transmembrane transporter activity
GO:0005515  protein binding
GO:0022857  transmembrane transporter activity
GO:0015250  water channel activity
GO:0005372  water transporter activity