inositol(myo)-1(or 4)-monophosphatase 1

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Synonym

inositol(myo)-1(or 4)-monophosphatase 1, IMPA1, Inositol-1(or 4)-monophosphatase, IMPA, IMP, Inositol monophosphatase, IMPase, Lithium-sensitive myo-inositol monophosphatase A1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:3.64 cerebellum:- brain stem:3.84 corpus callosum/glia:3.57 pineal gland:3.86 peripheral nerve:- spine:3.78 retina:- eye:- artery/aorta:2.74 vein:2.91 lymphnode:2.79 peripheral blood:- spleen:3.33 thymus:3.41 bone marrow:- adipose:3.26 bone:- skin:-
RNA-seq cerebrum:0.37 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:3.24 placenta:2.49 prostate:3.04 ovary:3.08 testis:4.09 heart:3.18 muscle:2.67 esophagus:3.54 stomach:- intestine:3.92 colon:2.94     liver/hepato:3.56    lung:3.24 bladder:3.13 kidney:3.98 pituitary:3.79 thyroid/parathyroid:3.45 adrenal gland:- pancreas:1.98 breast:2.41 salivary:3.15
RNA-seq uterus:- placenta:- prostate:0.13 ovary:0.00 testis:0.06 heart:0.65 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.37        lung:0.61    bladder:- kidney:0.36 pituitary:- thyroid/parathyroid:0.40 adrenal gland:0.84 pancreas:- breast:0.17 salivary:-

Gene Information

IDs

Refseq ID NM_001144879
Gene ID 3612
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000133731
GTEx ID ENSG00000133731

Orthologous Gene

Mouse[2]  NM_018864
Rat[1]  NM_032057

Chromosomal Region

8q21.13  [82,570,196  -  82,598,928]

Gene Family (Interpro ID)

IPR000760  Inositol monophosphatase
IPR020552  Inositol monophosphatase, Lithium-sensitive

Link to Pubmed  (Pubmed ID)

1332026
1377913
6253491
8068620
8068621
8718889
9210592
9339367
11281967
11911470
11959401
12176979
12477932
14699425
15342556
15489334
16189514
16344560
17068342
17207965
18029348
19322201
19447967
19593677
20153384
21139048
21890473
21906983
21963094
21965294
23027737
23535730
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006021  inositol biosynthetic process
GO:0046855  inositol phosphate dephosphorylation
GO:0043647  inositol phosphate metabolic process
GO:0006796  phosphate metabolic process
GO:0006661  phosphatidylinositol biosynthetic process
GO:0046854  phosphoinositide phosphorylation
GO:0007165  signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0008934  inositol-1(or 4)-monophosphatase activity
GO:0046872  metal ion binding
GO:0042803  protein homodimerization activity