integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)

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Synonym

MGC141996, Mucosal lymphocyte 1 antigen, Integrin alpha-E precursor, CD103 antigen, HUMINAE, HML-1 antigen, ITGAE, Integrin alpha-IEL, CD103

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:40.30 cerebellum:- brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:52.90 artery/aorta:60 vein:- lymphnode:111.20 peripheral blood:91.10 spleen:18.90 thymus:116 bone marrow:59 adipose:- bone:25.60 skin:9.60
GeneChip cerebrum:7.72 cerebellum:7.72 brain stem:7.78 corpus callosum/glia:7.90 pineal gland:- peripheral nerve:7.91 spine:7.89 retina:- eye:- artery/aorta:7.48 vein:7.78 lymphnode:8.42 peripheral blood:- spleen:8.60 thymus:9.09 bone marrow:8.04 adipose:8.21 bone:- skin:7.76
CAGE cerebrum:2.81 cerebellum:- brain stem:2.68 corpus callosum/glia:2.53 pineal gland:2.88 peripheral nerve:- spine:2.78 retina:- eye:- artery/aorta:2.58 vein:2.90 lymphnode:2.98 peripheral blood:- spleen:2.76 thymus:2.79 bone marrow:- adipose:2.41 bone:- skin:-
RNA-seq cerebrum:1.37 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.38 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.11 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:10.90 prostate:78.90 ovary:37.30 testis:43.30 heart:127.70 muscle:20.10 esophagus:- stomach:85 intestine:- colon:17     liver/hepato:42.20        lung:68.40    bladder:- kidney:124.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:18.60 salivary:-
GeneChip uterus:7.97 placenta:6.87 prostate:7.90 ovary:7.93 testis:8.49 heart:7.70 muscle:8.35 esophagus:8.12 stomach:8.20 intestine:8.23 colon:7.77 liver/hepato:7.13 lung:8.26 bladder:- kidney:7.84 pituitary:7.35 thyroid/parathyroid:7.90 adrenal gland:8.12 pancreas:7.69 breast:7.82 salivary:8.03
CAGE uterus:2.23 placenta:1.66 prostate:2.22 ovary:1.76 testis:2.31 heart:2.36 muscle:2.35 esophagus:2.40 stomach:- intestine:3.20 colon:2.96     liver/hepato:1.81    lung:2.94 bladder:2.00 kidney:2.29 pituitary:2.55 thyroid/parathyroid:2.22 adrenal gland:- pancreas:2.08 breast:3.27 salivary:2.60
RNA-seq uterus:- placenta:- prostate:1.69 ovary:1.48 testis:1.99 heart:1.07 muscle:0.71 esophagus:- stomach:- intestine:- colon:1.49     liver/hepato:0.75        lung:1.64    bladder:- kidney:1.56 pituitary:- thyroid/parathyroid:1.43 adrenal gland:2.17 pancreas:- breast:2.09 salivary:-

Gene Information

IDs

Refseq ID NM_002208
Gene ID 3682
Unigene ID Hs.513867
Probe set ID 205055_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000083457
GTEx ID ENSG00000083457

Orthologous Gene

Mouse[2]  NM_008399, NM_172944
Rat[2]  NM_008399, NM_172944

Chromosomal Region

17p13.2  [3,617,920  -  3,704,537]

Gene Family (Interpro ID)

IPR013517  FG-GAP
IPR013519  Integrin alpha beta-propellor

Link to Pubmed  (Pubmed ID)

1542691
3498635
7614974
8119947
8526015
8580465
9676575
9765275
10673275
10790430
10837471
10978890
11311556
12370249
12414996
12434297
12477932
14532999
15196058
15489334
16169070
16177076
16216886
16920912
17325197
17975119
18182176
18492951
18839057
19023099
19074885
19150377
19604725
20237496
20379614
20417566
20588308
20875079
21739671
21917686
21948982
22505724
22922816
24250222
24477908

Gene Ontology  (GO ID)

Biological Process

GO:0007155  cell adhesion
GO:0007229  integrin-mediated signaling pathway

Cellular Component

GO:0009897  external side of plasma membrane
GO:0008305  integrin complex
GO:0005886  plasma membrane

Molecular Function

GO:0046872  metal ion binding