inositol 1,4,5-trisphosphate 3-kinase B

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Synonym

Inositol-trisphosphate 3-kinase B, IP3K, IP3 3-kinase B, Inositol 1,4,5-trisphosphate 3-kinase B, ITPKB, PIG37, IP3K B, inositol 1,4,5-trisphosphate 3-kinase B, IP3K-B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:49.80 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:184 spine:112.30 retina:- eye:117.50 artery/aorta:- vein:- lymphnode:293.20 peripheral blood:36.40 spleen:56.70 thymus:64.40 bone marrow:59 adipose:80.70 bone:51.20 skin:48
GeneChip cerebrum:8.02 cerebellum:6.61 brain stem:8.60 corpus callosum/glia:8.63 pineal gland:- peripheral nerve:6.78 spine:8.68 retina:- eye:- artery/aorta:6.29 vein:6.10 lymphnode:7.03 peripheral blood:- spleen:7.20 thymus:7.87 bone marrow:6.27 adipose:6.71 bone:- skin:6.69
CAGE cerebrum:4.90 cerebellum:- brain stem:5.14 corpus callosum/glia:5.37 pineal gland:3.60 peripheral nerve:- spine:6.11 retina:- eye:- artery/aorta:4.06 vein:4.36 lymphnode:4.48 peripheral blood:- spleen:3.86 thymus:4.64 bone marrow:- adipose:4.16 bone:- skin:-
RNA-seq cerebrum:5.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.08 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.49 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:7.30 prostate:33.80 ovary:149.10 testis:17.30 heart:63.90 muscle:20.10 esophagus:342.80 stomach:- intestine:64.80 colon:93.30     liver/hepato:-        lung:34.20    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:8.90 breast:55.80 salivary:-
GeneChip uterus:7.19 placenta:5.98 prostate:6.81 ovary:6.66 testis:5.07 heart:5.84 muscle:5.59 esophagus:6.22 stomach:6.47 intestine:6.29 colon:6.66 liver/hepato:4.86 lung:6.62 bladder:- kidney:6.65 pituitary:5.25 thyroid/parathyroid:5.60 adrenal gland:5.40 pancreas:4.78 breast:6.71 salivary:7.25
CAGE uterus:4.57 placenta:3.11 prostate:4.13 ovary:3.40 testis:2.61 heart:3.72 muscle:2.63 esophagus:4.09 stomach:- intestine:3.47 colon:4.27     liver/hepato:1.86    lung:4.46 bladder:4.74 kidney:3.21 pituitary:2.59 thyroid/parathyroid:2.97 adrenal gland:- pancreas:2.34 breast:4.68 salivary:4.11
RNA-seq uterus:- placenta:- prostate:4.99 ovary:3.11 testis:2.57 heart:2.14 muscle:0.92 esophagus:- stomach:- intestine:- colon:3.79     liver/hepato:0.83        lung:4.61    bladder:- kidney:3.02 pituitary:- thyroid/parathyroid:2.80 adrenal gland:3.38 pancreas:- breast:3.50 salivary:-

Gene Information

IDs

Refseq ID NM_002221
Gene ID 3707
Unigene ID Hs.528087
Probe set ID 203723_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000143772
GTEx ID ENSG00000143772

Orthologous Gene

Mouse[2]  NM_001081175
Rat [0]  

Chromosomal Region

1q42.12  [226,819,391  -  226,927,024]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1330886
1654894
2176078
8889548
9374536
11104677
11846419
12477932
12747803
14702039
15489334
16189514
16354157
16710414
16740130
19322201
19913121
20379614
20628086
21148483
22446005
22589738
24401760

Gene Ontology  (GO ID)

Biological Process

GO:0007166  cell surface receptor linked signal transduction
GO:0043647  inositol phosphate metabolic process
GO:0000165  MAPKKK cascade
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0046579  positive regulation of Ras protein signal transduction
GO:0045059  positive thymic T cell selection
GO:0007165  signal transduction

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0005516  calmodulin binding
GO:0008440  inositol trisphosphate 3-kinase activity
GO:0005515  protein binding