inositol 1,4,5-triphosphate receptor, type 1

Synonym

IP3R1, inositol 1,4,5-triphosphate receptor, type 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3 receptor isoform 1, Insp3r1, Inositol 1,4,5-trisphosphate receptor type 1, ITPR1, InsP3R1, IP3R, INSP3R1, Type 1 InsP3 receptor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:7.08

cerebellum:8.89

brain stem:6.28

corpus callosum/glia:4.51

pineal gland:-

peripheral nerve:5.56

spine:4.94

retina:-

eye:-

artery/aorta:7.41

vein:6.99

lymphnode:6.53

peripheral blood:-

spleen:6.76

thymus:6.77

bone marrow:4.53

adipose:5.82

bone:-

skin:5.44

CAGE

cerebrum:4.16

cerebellum:-

brain stem:2.91

corpus callosum/glia:2.92

pineal gland:4.54

peripheral nerve:-

spine:2.39

retina:-

eye:-

artery/aorta:4.15

vein:3.65

lymphnode:3.71

peripheral blood:-

spleen:3.75

thymus:3.71

bone marrow:-

adipose:3.44

bone:-

skin:-

RNA-seq

cerebrum:3.06

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.27

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.24

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:7.25

placenta:5.26

prostate:7.49

ovary:7.54

testis:5

heart:6.33

muscle:3.96

esophagus:5.31

stomach:6.47

intestine:5.72

colon:5.47

liver/hepato:4.29

lung:6.75

bladder:-

kidney:6.84

pituitary:7.26

thyroid/parathyroid:8.11

adrenal gland:6.92

pancreas:4.29

breast:6.89

salivary:6.90

CAGE

uterus:4.50

placenta:2.76

prostate:4.58

ovary:4.29

testis:3.28

heart:3.27

muscle:2.19

esophagus:3.59

stomach:-

intestine:2.84

colon:3.25

liver/hepato:2.80

lung:3.51

bladder:4.40

kidney:3.41

pituitary:3.58

thyroid/parathyroid:4.04

adrenal gland:-

pancreas:1.59

breast:2.59

salivary:4.31

RNA-seq

uterus:-

placenta:-

prostate:3.57

ovary:2.65

testis:2.57

heart:1.18

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:1.04

bladder:-

kidney:0.13

pituitary:-

thyroid/parathyroid:2.76

adrenal gland:2.49

pancreas:-

breast:1.71

salivary:-

IDs

Refseq ID	NM_001099952
Gene ID	3708
Unigene ID	-
Probe set ID	203710_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000150995
GTEx ID	ENSG00000150995

Orthologous Gene

Mouse[2]	NM_010585
Rat [0]

Chromosomal Region

3p26.1 [4,535,032 - 4,889,524]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007202	activation of phospholipase C activity
GO:0070059	apoptosis in response to endoplasmic reticulum stress
GO:0007596	blood coagulation
GO:0006816	calcium ion transport
GO:0006112	energy reserve metabolic process
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0045087	innate immune response
GO:0048016	inositol phosphate-mediated signaling
GO:0048011	nerve growth factor receptor signaling pathway
GO:0030168	platelet activation
GO:0050796	regulation of insulin secretion
GO:0051209	release of sequestered calcium ion into cytosol
GO:0001666	response to hypoxia
GO:0007165	signal transduction

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral to membrane
GO:0031088	platelet dense granule membrane
GO:0031094	platelet dense tubular network
GO:0031095	platelet dense tubular network membrane

Molecular Function

GO:0015085	calcium ion transmembrane transporter activity
GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005218	intracellular ligand-gated calcium channel activity
GO:0035091	phosphoinositide binding
GO:0005515	protein binding

inositol 1,4,5-triphosphate receptor, type 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function