inositol 1,4,5-triphosphate receptor, type 3

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Synonym

ITPR3, Type 3 inositol 1,4,5-trisphosphate receptor, IP3 receptor isoform 3, inositol 1,4,5-triphosphate receptor, type 3, IP3R3, FLJ36205, Type 3 InsP3 receptor, InsP3R3, Inositol 1,4,5-trisphosphate receptor type 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:34.40 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:122.70 spine:336.90 retina:- eye:29.40 artery/aorta:30 vein:- lymphnode:161.80 peripheral blood:18.20 spleen:56.70 thymus:103.10 bone marrow:- adipose:- bone:102.40 skin:182.40
GeneChip cerebrum:5.67 cerebellum:5.28 brain stem:5.77 corpus callosum/glia:5.73 pineal gland:- peripheral nerve:8.41 spine:6.20 retina:- eye:- artery/aorta:6.93 vein:6.58 lymphnode:8.17 peripheral blood:- spleen:8.82 thymus:7.60 bone marrow:6.34 adipose:7.28 bone:- skin:8.37
CAGE cerebrum:1.10 cerebellum:- brain stem:1.69 corpus callosum/glia:0.82 pineal gland:1.68 peripheral nerve:- spine:1.96 retina:- eye:- artery/aorta:2.30 vein:2.67 lymphnode:2.93 peripheral blood:- spleen:3.33 thymus:2.57 bone marrow:- adipose:2.53 bone:- skin:-
RNA-seq cerebrum:0.67 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.29 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.55 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:7.30 prostate:22.50 ovary:37.30 testis:103.80 heart:38.30 muscle:- esophagus:- stomach:21.20 intestine:64.80 colon:407     liver/hepato:21.10        lung:102.60    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:148.70 salivary:-
GeneChip uterus:6.88 placenta:6.43 prostate:7.09 ovary:7.27 testis:8.03 heart:6.87 muscle:6.07 esophagus:7.70 stomach:8.38 intestine:7.51 colon:8.42 liver/hepato:6.08 lung:8.36 bladder:- kidney:6.80 pituitary:6.28 thyroid/parathyroid:8.68 adrenal gland:7.24 pancreas:6.49 breast:7.81 salivary:7.25
CAGE uterus:2.48 placenta:1.77 prostate:2.46 ovary:2.02 testis:3.44 heart:2.62 muscle:1.28 esophagus:2.69 stomach:- intestine:4.10 colon:3.93     liver/hepato:0.63    lung:3.59 bladder:2.13 kidney:2.54 pituitary:1.98 thyroid/parathyroid:3.59 adrenal gland:- pancreas:2.71 breast:2.59 salivary:2.80
RNA-seq uterus:- placenta:- prostate:2.20 ovary:2.09 testis:2.04 heart:1.02 muscle:0.63 esophagus:- stomach:- intestine:- colon:1.80     liver/hepato:0.30        lung:3.04    bladder:- kidney:2.42 pituitary:- thyroid/parathyroid:3.71 adrenal gland:2.44 pancreas:- breast:1.19 salivary:-

Gene Information

IDs

Refseq ID NM_002224
Gene ID 3710
Unigene ID Hs.65758
Probe set ID 201189_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000096433
GTEx ID ENSG00000096433

Orthologous Gene

Mouse[1]  NM_080553
Rat [0]  

Chromosomal Region

6p21.31  [33,588,522  -  33,664,351]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1693919
7559486
8081734
8288584
8385102
8388391
10611319
10692497
10828023
10843712
10874040
10980191
11035010
11149946
11163362
11290752
11413485
11524429
12032348
12477932
12606721
14666665
14685260
14702039
14707143
15051494
15623527
16960798
17081983
17437169
17496801
18219441
18275062
18340361
18434505
18539593
18544901
18586264
18826956
19050248
19052258
19193873
19389623
19553259
19553469
19596686
19706527
19730683
19851445
19913121
19946888
20103623
20379614
20395455
20427533
20558539
20618519
20628086
20660057
20881960
21075448
21139048
21501587
21762810
21875593
21890473
21900946
21906983
21963094
22082873
22100703
22552281
22586326
22939629
23618877
23722424
23850713
23955339
23983250
23992640
24469450

Gene Ontology  (GO ID)

Biological Process

GO:0007202  activation of phospholipase C activity
GO:0007596  blood coagulation
GO:0060402  calcium ion transport into cytosol
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0006112  energy reserve metabolic process
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0045087  innate immune response
GO:0060291  long-term synaptic potentiation
GO:0007613  memory
GO:0048011  nerve growth factor receptor signaling pathway
GO:0030168  platelet activation
GO:0051291  protein heterooligomerization
GO:0051260  protein homooligomerization
GO:0050796  regulation of insulin secretion
GO:0051592  response to calcium ion
GO:0050913  sensory perception of bitter taste
GO:0050916  sensory perception of sweet taste
GO:0050917  sensory perception of umami taste
GO:0007165  signal transduction

Cellular Component

GO:0045177  apical part of cell
GO:0005903  brush border
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005887  integral to plasma membrane
GO:0043209  myelin sheath
GO:0005640  nuclear outer membrane
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005886  plasma membrane
GO:0031095  platelet dense tubular network membrane

Molecular Function

GO:0043533  inositol 1,3,4,5 tetrakisphosphate binding
GO:0070679  inositol 1,4,5 trisphosphate binding
GO:0005220  inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0000822  inositol hexakisphosphate binding
GO:0005218  intracellular ligand-gated calcium channel activity
GO:0035091  phosphoinositide binding
GO:0005515  protein binding