junction plakoglobin

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Synonym

PKGB, junction plakoglobin, CTNNG, DPIII, DP3, Junction plakoglobin, Desmoplakin III, PDGB, JUP, Desmoplakin-3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:24.90

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:122.70

spine:-

retina:-

eye:117.50

artery/aorta:-

vein:-

lymphnode:10.10

peripheral blood:18.20

spleen:-

thymus:12.90

bone marrow:19.70

adipose:40.30

bone:25.60

skin:206.40

GeneChip

cerebrum:6.09

cerebellum:6.11

brain stem:6.19

corpus callosum/glia:6.86

pineal gland:-

peripheral nerve:7.41

spine:6.57

retina:-

eye:-

artery/aorta:7.14

vein:6.99

lymphnode:8.18

peripheral blood:-

spleen:6.83

thymus:6.53

bone marrow:6.02

adipose:7.71

bone:-

skin:9.71

CAGE

cerebrum:2.88

cerebellum:-

brain stem:3.31

corpus callosum/glia:3.94

pineal gland:2.50

peripheral nerve:-

spine:3.23

retina:-

eye:-

artery/aorta:3.82

vein:4.23

lymphnode:4.68

peripheral blood:-

spleen:3.28

thymus:3.99

bone marrow:-

adipose:4.32

bone:-

skin:-

RNA-seq

cerebrum:1.98

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.02

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.62

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:80.10

prostate:45.10

ovary:298.10

testis:4.30

heart:38.30

muscle:20.10

esophagus:-

stomach:42.50

intestine:-

colon:373.10

liver/hepato:21.10

lung:58.70

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:17.80

breast:297.40

salivary:-

GeneChip

uterus:7.49

placenta:8.31

prostate:7.70

ovary:7.44

testis:6.13

heart:7.97

muscle:7.12

esophagus:10.95

stomach:7.86

intestine:7.76

colon:8.41

liver/hepato:7.53

lung:7.91

bladder:-

kidney:8.92

pituitary:7.71

thyroid/parathyroid:8.69

adrenal gland:7.03

pancreas:6.98

breast:9.23

salivary:8.25

CAGE

uterus:4.94

placenta:5.44

prostate:4.49

ovary:4.32

testis:3.25

heart:4.75

muscle:4.24

esophagus:6.75

stomach:-

intestine:5.32

colon:4.80

liver/hepato:4.09

lung:4.40

bladder:3.99

kidney:5.18

pituitary:3.20

thyroid/parathyroid:5.03

adrenal gland:-

pancreas:4.20

breast:4.38

salivary:4.90

RNA-seq

uterus:-

placenta:-

prostate:4.05

ovary:3.82

testis:2.56

heart:4.42

muscle:4.45

esophagus:-

stomach:-

intestine:-

colon:2.47

liver/hepato:3.42

lung:4.34

bladder:-

kidney:4.75

pituitary:-

thyroid/parathyroid:5.50

adrenal gland:2.85

pancreas:-

breast:3.99

salivary:-

IDs

Refseq ID	NM_021991
Gene ID	3728
Unigene ID	Hs.514174
Probe set ID	201015_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000173801
GTEx ID	ENSG00000173801

Orthologous Gene

Mouse [0]
Rat [0]

Chromosomal Region

17q21.2 [39,775,692 - 39,943,183]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001664	Intermediate filament protein
IPR002957	Keratin, type I

Gene Ontology (GO ID)

Biological Process

GO:0034332	adherens junction organization
GO:0003181	atrioventricular valve morphogenesis
GO:0003136	canonical Wnt receptor signaling pathway involved in heart induction
GO:0034329	cell junction assembly
GO:0016477	cell migration
GO:0000902	cell morphogenesis
GO:0016337	cell-cell adhesion
GO:0045216	cell-cell junction organization
GO:0007016	cytoskeletal anchoring at plasma membrane
GO:0050982	detection of mechanical stimulus
GO:0007398	ectoderm development
GO:0007369	gastrulation
GO:0016331	morphogenesis of embryonic epithelium
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development
GO:0007399	nervous system development
GO:0048599	oocyte development
GO:0042307	positive regulation of protein import into nucleus
GO:0051091	positive regulation of transcription factor activity
GO:0051291	protein heterooligomerization
GO:0042127	regulation of cell proliferation
GO:0043588	skin development

Cellular Component

GO:0015629	actin cytoskeleton
GO:0016327	apicolateral plasma membrane
GO:0016323	basolateral plasma membrane
GO:0016342	catenin complex
GO:0005913	cell-cell adherens junction
GO:0005911	cell-cell junction
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0030057	desmosome
GO:0005916	fascia adherens
GO:0030056	hemidesmosome
GO:0014704	intercalated disc
GO:0005882	intermediate filament
GO:0009898	internal side of plasma membrane
GO:0016328	lateral plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0032993	protein-DNA complex
GO:0005667	transcription factor complex
GO:0030018	Z disc
GO:0005915	zonula adherens

Molecular Function

GO:0045294	alpha-catenin binding
GO:0045296	cadherin binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding
GO:0005199	structural constituent of cell wall
GO:0005198	structural molecule activity
GO:0003713	transcription coactivator activity

junction plakoglobin

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function