potassium inwardly-rectifying channel, subfamily J, member 2

Synonym

IRK1, LQT7, Kir2.1, HIRK1, Inward rectifier potassium channel 2, Cardiac inward rectifier potassium channel, HHBIRK1, KCNJ2, SQT3, HHIRK1, KIR2.1, Inward rectifier K(+) channel Kir2.1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:21.30

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:7.63

cerebellum:5.37

brain stem:7.75

corpus callosum/glia:9.08

pineal gland:-

peripheral nerve:5.58

spine:8.30

retina:-

eye:-

artery/aorta:5.07

vein:5.90

lymphnode:5.54

peripheral blood:-

spleen:6.24

thymus:5.74

bone marrow:5.63

adipose:5.67

bone:-

skin:5.53

CAGE

cerebrum:2.97

cerebellum:-

brain stem:3.74

corpus callosum/glia:4.07

pineal gland:1.53

peripheral nerve:-

spine:3.88

retina:-

eye:-

artery/aorta:2.10

vein:1.73

lymphnode:2.03

peripheral blood:-

spleen:2.82

thymus:1.28

bone marrow:-

adipose:2.01

bone:-

skin:-

RNA-seq

cerebrum:1.57

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.17

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.89

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:1971.70

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.26

placenta:7.63

prostate:5.63

ovary:6.75

testis:4.28

heart:7.59

muscle:8.24

esophagus:6.33

stomach:5.26

intestine:5.57

colon:5.92

liver/hepato:4.84

lung:5.80

bladder:-

kidney:5.07

pituitary:5.07

thyroid/parathyroid:4.89

adrenal gland:4.99

pancreas:5.25

breast:6.48

salivary:4.76

CAGE

uterus:1.32

placenta:3.12

prostate:1.55

ovary:1.51

testis:0.79

heart:2.65

muscle:1.95

esophagus:1.66

stomach:-

intestine:0.93

colon:1.90

liver/hepato:0.63

lung:2.27

bladder:1.32

kidney:0.58

pituitary:1.02

thyroid/parathyroid:1.19

adrenal gland:-

pancreas:0.58

breast:2.47

salivary:0.62

RNA-seq

uterus:-

placenta:-

prostate:1.10

ovary:1.19

testis:1.02

heart:3.38

muscle:2.71

esophagus:-

stomach:-

intestine:-

colon:1.06

liver/hepato:0.38

lung:1.42

bladder:-

kidney:0.67

pituitary:-

thyroid/parathyroid:1.02

adrenal gland:0.89

pancreas:-

breast:1.88

salivary:-

IDs

Refseq ID	NM_000891
Gene ID	3759
Unigene ID	Hs.154704
Probe set ID	206765_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000123700
GTEx ID	ENSG00000123700

Orthologous Gene

Mouse[1]	NM_008425
Rat [0]

Chromosomal Region

17q24.3 [68,164,814 - 68,176,160]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016449	Potassium channel, inwardly rectifying, Kir
IPR001838	Potassium channel, inwardly rectifying, Kir-like
IPR003271	Potassium channel, inwardly rectifying, Kir2.1

Gene Ontology (GO ID)

Biological Process

GO:0030007	cellular potassium ion homeostasis
GO:0015693	magnesium ion transport
GO:0010107	potassium ion import
GO:0006813	potassium ion transport
GO:0051289	protein homotetramerization
GO:0060306	regulation of membrane repolarization
GO:0060075	regulation of resting membrane potential
GO:0014861	regulation of skeletal muscle contraction via membrane action potential
GO:0055119	relaxation of cardiac muscle
GO:0090076	relaxation of skeletal muscle
GO:0007268	synaptic transmission

Cellular Component

GO:0043025	cell soma
GO:0030425	dendrite
GO:0005887	integral to plasma membrane
GO:0031224	intrinsic to membrane
GO:0005886	plasma membrane
GO:0008076	voltage-gated potassium channel complex

Molecular Function

GO:0042802	identical protein binding
GO:0005242	inward rectifier potassium channel activity
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

potassium inwardly-rectifying channel, subfamily J, member 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function